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Biomedical subjects

M Sandbank

Publications and source records attributed to M Sandbank.

160 records · Page 9Linked to original sources

The role of lysosomes in the healing process of cutaneous leishmaniasis.

Biopsy material in early and late stages of cutaneous leishmaniasis was obtained. The ultrastructural study using acid phosphatase reaction as a marker for lysosomes showed that in early stages parasites proliferate undisturbed within macrophage cytoplasm. At later stages numerous degenerating parasites were seen and macrophage lysosomes were observed adhering to and pouring their contents into the parasite. It is assumed that activated macrophages control intracellular parasitism by lysosomal activity.

Adult↗

Asymptomatic liver injury due to erythromycin stearate.

A 73-year-old woman with rosacea, who had started treatment with erythromycin stearate 2 g/d, developed asymptomatic liver injury. The drug was discontinued and the laboratory findings of liver damage disappeared within 11 days. This is the first report of erythromycin stearate-induced asymptomatic hepatotoxicity.

Aged↗