Peripheral aneurysms of the middle cerebral artery.
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Adolescent↗
Biomedical subjects
M Salama
Publications and source records attributed to M Salama.
Impact of aging and diabetes mellitus on the expression of the proliferating cell nuclear antigen in rat testicular tissue.
This study evaluated the expression of proliferating cell nuclear antigen (PCNA), which is one of the important markers of cell proliferation, in testicular tissue with aging and progress of diabetes mellitus (DM). OLETF rats were used as animal models for non-insulin-dependent DM. They were 12, 30, 50, and 70 weeks old. The controls were age-matched nondiabetic LEIO rats. Testes were taken from all the rats and paraffin-embedded sections were cut and stained with PC 10 monoclonal AB (x50). Labeled cells were assessed in randomly selected fields. Labeling index (LI) for each stage of spermatogenesis was estimated and total LI for each specimen was calculated. In control rats, the 12-week-old animals showed the highest PCNA-LI. The indexes started to decrease in other older animals, with an increase in the number of suppressed stages as the animals aged, leading to significant differences among groups except between the 12- and 30-week-old groups. The same features were also seen in DM animals as the disease progressed. The total LI of controls were significantly higher and the number of suppressed stages was lower than those of DM animals, except among the 12-week-old group. Both aging and DM have depressing effects on the expression of PCNA in testicular tissue. The decline in PCNA expression is parallel with advancement of age and progress of DM. However, DM has a more suppressing effect than aging on that expression. This suppression could explain the decrease in male fertility potential that may be associated with both conditions.
Aging↗
Specificity of visual evoked potentials alterations in Alzheimer's disease: comparison with normal aging, depression and scopolamine administration in young healthy volunteers.
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Adult↗
The orthodontic-periodontal connection in implant site development.
Implant-supported restorations have become an established treatment modality, well accepted by patients and clinicians. Regaining function is now routinely expected, and the focus of patient demand has shifted to aesthetics. Aesthetic restoration of the partially edentulous anterior maxilla can be particularly challenging. The learning objective of this article is to present a comprehensive multidisciplinary treatment protocol, developed to establish a foundation for optimal aesthetics in implant therapy, with emphasis on the role of orthodontics in the enhancement of deficient components. Periodontal orthodontics is used to increase the vertical osseous dimension and preserve papillae; restorative orthodontics optimizes the site through manipulation of supragingival restorative space. Two clinical cases are utilized to illustrate the principles and implementation of this protocol.
Adult↗