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Biomedical subjects

M Saigusa

Publications and source records attributed to M Saigusa.

At least 37 records · Page 2Linked to original sources

Effects of intervening sinus beats on ectopic cycle length in a patient with ventricular parasystole.

The intrinsic cycle length of the ventricular parasystolic pacemaker may be modulated by electrotonic influence of intervening ventricular depolarizations. In order to quantify the magnitude of modulation in relation to the timing of the intervening depolarization, a curve of influence was constructed in a patient with ventricular parasystole. The current communication deals with the detailed description of a step-by-step method for the construction of the curve of influence.

Adult↗

Relationship between renin activity and aldosterone release in the patients with low cardiac output syndrome after open cardiac surgery.

Plasma renin activity and aldosterone concentration were measured by radioimmunoassay technique in seven patients with low cardiac output syndrome after open cardiac surgery. Plasma renin activity and aldosterone concentration markedly increased, and plasma renin activity was well correlated with plasma aldosterone concentration. Plasma renin activity and aldosterone concentration, however, had no direct correlation with plasma sodium and potassium concentration or administered doses of inotropic agent, potassium and diuretic. Sodium and potassium balance was closely correlated with plasma aldosterone concentration. In the present study, it was suggested that the secondary hyperaldosteronism following low cardiac output syndrome after open cardiac surgery was mainly induced by the increased release of renin and that it influenced on the balance of sodium and potassium metabolism under such disturbed circulatory circumstances.

Adolescent↗

Apparent suppression of ventricular parasystole by cardiac pacing.

Complete disappearance of ventricular parasystolic beats by cardiac pacing with the rates of near multiples of the parasystolic rate was observed in 2 patients with ventricular parasystole. This finding represents a clinical counterpart of recently demonstrated experimental and mathematical models of electrotonic modulation of the parasystolic discharge.

Adolescent↗