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M S Fox

Publications and source records attributed to M S Fox.

78 records · Page 5Linked to original sources
PubMed1968

Fractionation of transformable bacteria from ocompetent cultures of Bacillus subtilis on renografin gradients.

A population of Bacillus subtilis can be fractionated into at least two components on the basis of their buoyant densities on a Renografin gradient. In competent cultures, most, and perhaps all, of the competent bacteria appear in the lighter fraction which composes 2 to 10% of the bulk population. These "lighter" bacteria are the only bacteria capable of incorporating transforming deoxyribonucleic acid.

Bacillus subtilis↗
PubMed1966

On the mechanism of integration of transforming deoxyribonucleate.

The characteristics of the intermediates in the reaction, between DNA and pneumococcus, that results in genetic transformation are described in so far as they have been characterized. Transformation with DNA isolated from bacteria carrying in addition to genetic markers (32)P as a radioactive label and (2)H and (15)N as density labels has permitted the characterization of the product of recombination between the newly introduced DNA and the DNA of a recipient bacterium. The evidence for a single strand displacement mechanism producing a hybrid structure in the DNA of the recipient bacteria is presented. Progeny of single transformants have been examined. The results of these segregation studies permit the further characterization of this hybrid product of transformation as a genetically heterozygous structure.

Bacillus subtilis↗