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Biomedical subjects

M S Clark

Publications and source records attributed to M S Clark.

104 records · Page 6Linked to original sources
PubMedDate not supplied

An examination of the factor structure of the Frenchay Activities Index.

The Frenchay Activities Index (FAI) was administered to an elderly non-stroke subject group with the objective of evaluating the underlying factor structure of the index. Data analysis yielded three factors which were labelled indoor domestic chores, outdoor domestic chores, and outdoor social activities. This factor structure is compared with that previously published. It is argued that lifestyle activities should be considered within a framework which distinguishes between indoor/outdoor and work/leisure activities.

Activities of Daily Living↗
PubMedDate not supplied

Lifestyle activities of the elderly: composition and determinants.

Recent work suggests that lifestyle can be considered using a 2 x 2 model of indoor/outdoor and work/leisure activities. This paper replicates the factor analysis of the Frenchay Activities Index (FAI) reported by Bond et al., using a group of subjects living independently in the community. Results confirmed empirically the existence of the four hypothesized dimensions of lifestyle. Further analyses demonstrated the construct validity of these dimensions by establishing their sensitivity to age, sex, domestic circumstances, and physical and cognitive status. We discuss ways in which various deficiencies in the FAI might be rectified in a revised index of activities designed to retain and clarify the four established dimensions of lifestyle. Future directions include the development of such an instrument, and its application as a rehabilitation outcome measure.

Activities of Daily Living↗
PubMedDate not supplied

Reversal of central benzodiazepine effects by intravenous flumazenil.

The purpose of this study was to determine the efficacy of flumazenil in safely expediting patient recovery from benzodiazepine sedation. This double-blind, randomized, placebo-controlled study involved 30 patients who received conscious sedation induced by intravenous midazolam given for a dental surgical procedure. Patients who received flumazenil were rated significantly more alert than were placebo-treated patients at 5 and 15 min following test drug administration. They also had significantly superior scores on the digital symbol substitution test and on tests in a comprehensive modified neurological examination 5 min after receiving flumazenil. Group differences were not as impressive on recall and recognition tests. However, flumazenil patients scored somewhat more favorably than the placebo group patients in identifying simple objects they had been shown during the observation period following surgery. Flumazenil appears to be a promising drug for reversing midazolam conscious sedation.

Adult↗
PubMedDate not supplied

Clinical use and potential biohazards of nitrous/oxide oxygen.

This article examines the worldwide literature for information regarding the potential adverse effects of nitrous oxide on chronically exposed personnel. This research convincingly demonstrates the lack of substantiation for these concerns. Biologically correlated standards for exposure still need to be established. Nitrous oxide has never been implicated to be harmful in any way to the patient.

Air Pollutants, Occupational↗