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Biomedical subjects

M Roth

Publications and source records attributed to M Roth.

At least 379 records · Page 21Linked to original sources
PubMed1981

[Ultrasonic echography as a diagnostic measure before supra-pubic bladder puncture].

It is reported on 40 punctures of the bladder after previous ultrasound diagnostics. In all cases the puncture could be performed successfully without failure at a filling stage of the bladder of 250 to 300 ml. By this possibility to puncture the bladder at a physiological filling stage changes of the urine tests were avoided which appear by the often recommended methods for the increase of diuresis.

Cystitis↗
PubMed1981

[The limits of depressive illness (author's transl)].

There are a number of issues relating to the classification of affective disorders. Although they are closely interconnected, they have been considered in isolation from each other. The main issues that arise in this field are the relationship of bipolar and unipolar disorders, the importance of autonomous and neurotic forms of depression, the boundaries between depressive and anxiety disorders and the relationship of schizoaffective and kindred conditions to affective disorders. When these issues, considered in the past in isolation, are examined together, certain problems of classification of disorders of affect and their treatment are clarified and a number of questions are posed for future enquiry.

Anxiety Disorders↗
PubMed1980

Reduced cortical choline acetyltransferase activity in senile dementia of Alzheimer type is not accompanied by changes in vasoactive intestinal polypeptide.

Post-mortem brain tissue from 7 patients who died with a diagnosis of senile dementia of Alzheimer type (SDAT) was compared with tissue obtained from 7 control patients at routine post mortem. A significant fall in choline acetyltransferase (ChAT) activity was apparent in the cerebral cortex of the SDAT cases which was maximal in the temporal lobe. The fall in ChAT activity was not accompanied by changes in cortical vasoactive intestinal polypeptide (VIP) measured by radioimmunoassay.

Aged↗
PubMed1980

Exfoliation syndrome.

We reviewed the records of 74 patients with exfoliation syndrome. Patients with exfoliation syndrome represented 12% of the current Glaucoma Clinic population. There were 40 unilateral and 34 bilateral cases. Thirteen percent of the patients who originally had unilateral exfoliation later developed exfoliation in the fellow eye. Forty percent of the affected eyes with exfoliation had appreciable cataracts. Evidence for bilateral glaucoma was present in only 22% of the patients with unilateral exfoliation (and ipsilateral glaucoma). The evidence suggests that the exfoliation syndrome is, in most cases, the cause of the glaucoma, and that this is generally a true secondary open-angle glaucoma. Trabecular pigmentation may be a prognostic factor relating to the occurrence of glaucoma.

Aged↗
PubMed1980

Reduced amounts of immunoreactive somatostatin in the temporal cortex in senile dementia of Alzheimer type.

Post-mortem brain tissue from 15 patients dying with a diagnosis of senile dementia of Alzheimer type (SDAT) was compared with tissue obtained from 16 control patients at routine post-mortem. A significant fall in choline acetyltransferase (ChAT) activity was observed in the cortex, hippocampus and amygdala of the SDAT cases and was maximal in the temporal cortex. The fall in ChAT activity observed in the temporal cortex was accompanied by a significant reduction (47%) in immunoreactive somatostatin.

Aged↗
PubMed1979

Glaucoma associated with precipitates on the trabecular meshwork.

Precipitates on the trabecular meshwork may be the only sign of ocular inflammation. Fourteen patients who had glaucoma associated with precipitates on the trabecular meshwork and minimal or no other signs of ocular inflammation did not respond to usual antiglaucoma therapy. Treatment with topical steroids eliminated the precipitates and lowered the intraocular pressure. Careful gonioscopy is the key to accurate diagnosis.

Acetazolamide↗
PubMed1979

Study of peptides inhibiting the angiotensin-converting enzyme of human seminal plasma.

Several peptides were investigated for their inhibitory capacity against dipeptidyl carboxypeptidase (angiotensin-converting enzyme) from human seminal fluid. The strongest inhibitor was the nonapeptide SQ 20881. A marked inhibition was also shown by the compounds Phe-Ala-Pro and Boc-Phe-Ala-Pro, which behaved as competitive inhibitors. Among the peptides related to angiotensin, angiotensin III was the strongest inhibitor, followed by angiotensin II and the C-terminal hexapeptide of angiotensin II. The results indicate the dipeptidyl carboxypeptidase of human semen is very similar to pulmonary dipeptidyl carboxypeptidase in its susceptibility to peptide inhibitors. In view of these and other previously reported similarities, it is possible that both enzymes are identical.

Angiotensin II↗