In a general hospital, 391 consecutive necropsies in which at least seven organs were available, were examined retrospectively by polarizing microscopy of Congo-red-stained sections for the presence of local amyloid deposits.Non-systemic microdeposits of amyloid were encountered in 72 cases, an overall incidence of 18.4%. They were usually small and frequently detectable only by virtue of polarizing microscopy. There is no indication that these microdeposits of amyloid are of pathogenetic significance. Although they sometimes occur in more than one organ, such deposits can be readily distinguished from those of systemic amyloidosis by their histological features.

Adrenal Glands↗

PubMedDate not supplied

Dupuytren's disease in diabetes mellitus.

Dupuytren's disease (DD) was demonstrated in 169 of 959 diabetics (17.6%) and in 9 of 1,396 non-diabetic patients (0.64%). One hundred and seventy-nine of the 185 patients with DD had overt or latent diabetes mellitus (96.7%). The relative frequency of DD increased with age, the conditions was seldom found under the age of 40. DD should be regarded as a non-hyperglycemic manifestation of diabetes mellitus and its presence in a patient should prompt the investigation of glucose metabolism.

Adult↗

PubMedDate not supplied

Risk factors for nephropathy in type 2 diabetes mellitus.

The main risk factors for diabetic nephropathy are hypertension, hyperlipidemia, and hyperglycemia. Nephropathy heralds the downhill course of arteriosclerosis. Early and intensive blood pressure and glucose control will attenuate the course of nephropathy and significantly reduce cardiovascular events and stroke.

Adult↗

PubMedDate not supplied

Painless thyroiditis followed by autoimmune disorders of the thyroid. A case report with biopsy.

Painless thyroiditis is a clinical entity of unknown origin. We report a case of a woman first seen with painless thyroiditis, who consequently developed a true hyperthyroidism, then exophthalmos and finally permanent hypothyroidism. The biopsy findings and serum antibodies determinations at the final stage were of Hashimoto's thyroiditis. The case is discussed and the need for a long follow-up after a painless thyroiditis is stressed.

Adult↗