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Biomedical subjects

M Ramos

Publications and source records attributed to M Ramos.

At least 181 records · Page 10Linked to original sources
PubMed1977

[Sequential cardiac szintigraphy: a methodological contribution to the evaluation of local cardiac dynamics].

A non-invasive technique is described in which the initial passage of a radionuclide is followed through the heart using an tanger camera after intravenous bolus injection. This method allows analysis of the regional and global wall motion of the left ventricle as well as estimation of the regional distribution of stroke volume and ejection fraction. Supplementing radionuclide angiocardiography with gradient scintigraphy permits the diagnosis of left ventricular aneurysms, intracardiac shunts and av-valve insufficiency. Initial comparisons show fair agreement between the radionuclide technique and left ventricular contrast angiography.

Angiocardiography↗
PubMed1977

[Evolution of tuberculosis and lung perfusion].

Ten patients with pulmonary tuberculosis of strikingly long duration despite intensive antituberculous therapy were examined by combined lung scintigraphy (133Xe in physiologic saline i.v. and 99mTc-MAA/microspheres). As a rule the scintigraphic perfusion defects far exceeded the lesions seen radiologically. These results appear to justify the presumption that the decrease - or even absence - of perfusion in the affected areas is responsible for protracted healing in these patients.

Adult↗
PubMed1977

[Selective double-isotope coronary scintigraphy with 99mTc- and 111In-HSA-microspheres].

A small fraction of a commercially available kit for the preparation of human serum albumin (HSA)-microspheres is labeled with 111In or 99mTc. The regional coronary blood flow is determined after selective injection of these labeled microspheres at rest and during rapid atrial pacing using a double-isotope coronary scintigraphy with a gamma camera.

Adult↗
PubMed1976

[The value of lung scintigraphy in the staging of bronchial carcinoma. Prospective study for the determination of TN stages].

A prospective study has been conducted to determine the clinical importance of lung scintigraphy in the work-up of patients thought to have bronchial carcinoma (i.e., accuracy of the scintigraphic diagnosis, data concerning spread of the primary tumor [=T] as well as the possibility of metastases to the lung hilus and mediastinum [=N]). Ninety-four patients, all of whom were hospitalized for suspected bronchial carcinoma, were examined by 133Xenon i.v., 133Xenon gas inhalation,, and 99mTc-MAA i.v. (macroaggregated albumin or microspheres of human albumin). The suspicion was confirmed in 77 patients. Central and peripheral bronchial carcinomas were kept separate in the evaluation. A normal lung scintigram practically rules out a central bronchial carcinoma. Where the scintigraphic finding prompts suspicion of central bronchial carcinoma, this suspicion must be confirmed by other examinations and preferably those which cytologically and histologically directly demonstrate the tumor. The diagnostic reliability of lung scintigraphy is drastically reduced in patients with bilateral ventilation disturbances. Because of its 27% rate of false negative findings, bronchoscopy is a less suitable means of ruling out bronchial carcinoma than scintigraphy. The peripheral bronchial carcinoma displays no characteristic scintigraphic signs; thus, a normal scintigram does not rule out peripheral bronchial carcinoma. Bronchoscopy was negative in all these patients. Spread of the primary tumor was exactly predicted with bronchoscopy in 11% and with scintigraphy in 42% of cases. When the scintigraphic criteria for hilar or mediastinal involvement are ful filled, it is practically certain that the patient is no longer radically operable. This assertion is valid when mediastinoscopy is normal. Lung scintigraphy possesses the same accuracy in the diagnosis of mediastinal involvement both with peripheral lung tumors and with centrally located tumors.

Bronchial Neoplasms↗
PubMed1976

[The reliability of scintigraphic criteria of the lungs concerning the estimation of mediastinal involvement in case of bronchial carcinoma (prospective study) (author's transl)].

The goal of this prospective study is to determine the reliability of the scintigraphic diagnosis of mediastinal involvement in patients with bronchial carcinoma, as well as to establish the value of each individual scintigraphic criterion. Ninety-four patients, all of whom were hospitalized because of suspicion of bronchial carcinoma were examined using 133-Xenon i.v., 133-Xenon gas inhalation, and 99m-Tc-MAA i.v. (macroaggregated albumin or microspheres of human albumin). The suspicion was confirmed in 77 patients. -The most reliable scintigraphic criteria are: 1. a localized delayed appearance of the activity in the afflicted lung area during the first 20 sec of the 133-Xenon i.v. series, and 2. the presence of a "dead-space" ventilation. Activity remaining in the area of the subclavian vein or the superior vena cava up to 10 min after the injection of 133-Xenon i.v. must be very carefully interpreted. Sixty-five patients underwent both mediastinoscopy and scintigraphy: in 44 patients (= 68%) the findings in both examinations were the same. Compared to the final diagnosis (mediastinoscopy, operation) there were 20 (= 30%) false negative but only one (= 2%) false positive scintigraphic diagnoses made. -When the scintigraphic criteria of hilar or mediastinal involvement are fulfilled, then the patient is practically certain to be no longer radically operable. This assertion is valid even when the mediastinoscopy is normal.

Bronchial Neoplasms↗
PubMed1976

[Dependence of regional lung function on posture: radiospirometric findings in health].

Ten healthy volunteers were examined radiospirometrically using 133Xenon in physiologic saline i.v. and with 133Xenon gas inhalation. The measurements were done using a gamma camera (Nuclear Chicago, Pho/Gamma III) in the PA projection in both sitting and supine positions. For evaluation, each lung was divided into three regions: upper, middle, and lower fields. Using a computer (DEC, GAMMA 11), the minute exhalation value, the perfusion and ventilation indices, and the ventilation/perfusion quotient were calculated. In the upright position the ventilation and perfusion indices increase from cranial to caudal. In the horizontal position the regional lung functions tend to equalize. The vital capacity is larger in the vertical position than in the horizontal position, particularly in the right lung. The values are shown in tabular form.

Adult↗
PubMed1975

[Reliability of positive findings in serial cerebral scintigraphy. Evaluation of a prospective series of 1700 cases].

The cerebral sequential scintigraphy enables a process to be described according to its hemodynamics (Stage I), its degree of vascularization (Stage II), and the extent of the localized disturbance of the blood-brain barrier function (Stage III). For a given lesion, typical scintigraphic behaviour patterns can be described. This report presents the results of a prospective series with 1722 patients examined using this method. The accuracy of the different scintigraphic diagnoses, according to tumor type, was: cerebrovascular accident with brain infarction - 92% (= CVA), metastasis - 90%, bone or meningital process - 89%, malignant glioma - 91%, meningioma - 74%, highly differentiated glioma - 67%, chronic subdural hematoma - 54%, A-V angioma - 54%, brain abscess - 45%. The differential diagnosis between brain tumor and CVA with infarction was possible in approximately 97% of the patients, the differential diagnosis of intracranial space-occupying lesion versus CVA with infarction in approximately 95%. There were 14 false positive results recorded (0.8% of the 1722 patients).

Brain Abscess↗
PubMed1975

Cerebral vasculitis in rheumatoid arthritis.

A 63-year-old man with severe, untreated rheumatoid arthritis and pleuritis developed an unusual neurological syndrome similar to Gerstman syndrome, followed by dementia and blindness, six weeks before his death. An autopsy showed extensive necrotizing vasculitis, resembling polyarteritis nodosa, involving the brain and resulting in numerous infarcts. The disease was most severe in the posterior portion of the cerebral hemispheres. Other organs were only slightly involved. Severe amyloidosis of cerebral arterioles and senile plaques were noted in the areas of brain with most severe vasculitis. Review of literature indicated only six cases of cerebral vasculitis in rheumatoid disease, five of which were treated with corticosteroids.

Arthritis, Rheumatoid↗
PubMed1975

Recurrent superior mesenteric artery syndrome in a quadriplegic patient.

Recurrent superior mesenteric artery syndrome occurs less frequently than other complications in patients having high spinal cord injury. However, as illustrated by the case reported here, it is important that the clinician be aware of the possibility of this syndrome in such patients.

Adolescent↗