Contraceptive distribution in Bangladesh: some lessons learned.
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Bangladesh↗
Biomedical subjects
M Rahman
Publications and source records attributed to M Rahman.
Pseudo-leptospires in blood culture.
Spiral filaments seen in the blood cultures of two patients with fever and jaundice were initially thought to be leptospires; these were later proved to be artefacts. An investigation was carried out to exclude the possibility of laboratory contamination of the culture media and to find out how these objects were produced. The significance of the findings is discussed in relation to the possibility of a mistaken diagnosis in routine laboratories which have a limited experience of leptospires.
Blood↗
Quality of specimens and sputum culture results: a retrospective study.
A retrospective study of laboratory reports of sputums examined in the first 3 months of 1977 and of 1978 showed some interesting findings, which were similar in these 2 years. Analysis of the findings demonstrated that information from a proportion of sputum cultures were not helpful to the clinicians. Probable causes of such unhelpful results and some ways to overcome these problems were discussed, along with reviews of relevant literature. A conclusion drawn at the end of the discussion was that, under present circumstances, it was not expected that sputum cultures would produce totally reliable aetiological agents, unless attempts were made to obtain a better quality of specimen, e.g. those obtained by transtracheal or bronchoscopic aspirations.
Bacteria↗
Urinary tract infection in school children.
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Adolescent↗
Outbreak of chickenpox and herpes zoster in a geriatric hospital.
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Aged↗
Antibiotic resistance in Streptococcus pneumoniae and Haemophilus influenzae.
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Anti-Bacterial Agents↗
Lincomycin and clindamycin resistant Bacteroides species.
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Bacteroides↗
Free-sporing Cl. welchii in ordinary laboratory media and conditions.
A strain of Clostridium welchii produced spores in ordinary blood agar plates. Investigations confirmed that it was the character of this particular strain and that the laboratory media were not inducing sporulation. During a period of 12 months a total of 100 strains of Cl. welchii were studied. None of them produced spores in ordinary laboratory media and conditions when examined microscopically.
Clostridium perfringens↗
Carbon dioxide-dependent Staphylococcus aureus from abscess.
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Adult↗
Pivmecillinam and amoxycillin as combined treatment in purulent exacerbations of chronic bronchitis.
One hundred and thirty-two patients with purulent exacerbations of chronic bronchitis were randomly allotted to treatment in three groups. They received (a) amoxycillin 250 mg and pivmecillinam 200 mg; or (b) amoxycillin 500 mg; or (c) amoxycillin 500 mg and pivmecillinam 400 mg: three times daily for 10 days. By the 7th day of treatment there was significant improvement over amoxycillin alone for both groups given combined chemotherapy in conversion of sputum to mucoid and in general improvement; at the end of treatment results in patients given the higher doses of both antibiotics were still superior to amoxycillin alone. Patients were observed 2 to 4 weeks later, when those given amoxycillin alone relapsed much more frequently. The three treatments were well tolerated and succeeded equally in clearing potential pathogens from the sputum. Combined treatment may be superior due to synergy against Haemophilus influenzae or to the elimination of beta-lactamase producing organisms and should be investigated further.
Aged↗
Amoxycillin and co-trimoxazole in acute purulent exacerbations of chronic bronchitis.
100 hospital patients suffered from acute exacerbations of chronic bronchitis. 50 were treated with amoxycillin in a dose of 500 mg, three times a day for 10 days and the results compared with 50 patients treated with co-trimoxazole in a dose up to 480 mg trimethoprim and 2,400 mg of sulphamethoxazole daily in males, and two thirds of this dose in females. The trial was single-blind. During the acute phase of infection, both treatments were equally effective in clinical improvement, conversion of the sputum from purulent to mucoid, diminution of quantity and elimination of pathogenic bacteria. Amoxycillin was quicker in sputum conversion and gave less side effects, but the differences were not significant. During the 2-4 weeks following treatment, only a third of the patients who had received co-trimoxazole remained well and free from purulent relapse, as opposed to 72% who had received amoxycillin, a difference significant at the 2% level.
Acute Disease↗
Preparation of anti-human globulin serum in Bangladeshi rabbits and goats.
Anti-human globulin was produced in local rabbits and goats by using human O serum mixed with Freund's adjuvants (complete or incomplete) for immunising the animals. A titre of 1/1024 was obtained in rabbit and a titre of 1/8192 was obtained in goat. Quality-and quantity-wise, goat's serum appeared to be better than rabbit's serum.
Animals↗
A survey of basic health information of rural Bangladesh.
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Bangladesh↗
Nephrotic syndrome.
The nephrotic syndrome is clinical entity having multiple etiology. In the present study, 70 cases of nephrotic syndrome both in children and adults have been studied. The condition appears to be more common than thought of. The histological classification is helpful both in management and forecasting the prognosis. Steorid and cytotoxic drugs have been used in light negative glomerulonephritis and lupus nephritis producing nephrotic syndrome with good results. The other forms of of glomerulonephritis needs further study to be able to offer any specific therapy.
Adult↗
Amoxycillin and co-trimoxazole in acute purulent exacerbations of chronic bronchitis.
100 hospital patients suffered from acute exacerbations of chronic bronchitis. 50 were treated with amoxycillin in a dose of 500 mg, three times a day for 10 days and the results compared with 50 patients treated with co-trimoxazole in a dose up to 480 mg trimethoprim and 2,400 mg of sulphamethoxazole daily in males, and two thirds of this dose in females. The trial was single-blind. During the acute phase of infection, both treatments were equally effective in clinical improvement, conversion of the sputum from purulent to mucoid, diminution of quantity and elimination of pathogenic bacteria. Amoxycillin was quicker in sputum conversion and gave less side effects, but the differences were not significant. During the 2-4 weeks following treatment, only a third of the patients who had received co-trimoxazole remained well and free from purulent relapse, as opposed to 72% who had received amoxycillin, a difference significant at the 2% level.
Amoxicillin↗
A clinical trial of temazepam, a sleep inducer, in hospital patients.
Temazepam, a common metabolite of diazepam and oxazepam, was evaluated as a sleep inducer. A dose of 20 mg, in a Scherer capsule formulation, was compared with 200 mg of amylobarbitone sodium in a between-patients, randomized study. Patient and staff assessments were used. No statistically significant difference as to onset of sleep, duration or quality of sleep or morning drowsiness was found using the patients' assessments. The staff recorded significantly less daytime dozing and morning hangover in patients receiving temazepam. Side-effects were mild and confined mainly to drowsiness on awakening. Two patients, both on amylobarbitone sodium, withdrew from the study because of increasing confusion.
Aged↗
Non-association of ABO blood groups with diabetes mellitus in Bangladesh.
Confirmed diabetics (2312) were tested for ABO blood groupings and the results of frequency compared with normal (8936) subjects. The data were analysed statistically to detect any possibility of an association between ABO blood groups and diabetes mellitus. No such association is apparent in the subjects studied.
ABO Blood-Group System↗
The causal role of hypoalbuminemia in human nephrotic hyperlipidemia.
Serum lipids and their lipoprotein fractions were measured in 16 nephrotic syndrome patients. All component of lipids and beta-lipoprotein fractions (LDL) showed an increase in all uncomplicated patients. The increase in serum lipids were inversely proportional to the albumen level in these patients. In 3 patients, lipids and beta-lipoprotein fractions returned to near normal after treatment, the proteinuria diminished and serum albumen became normal. Most of these patients did not need any treatment for hyperlipidemia.
Adolescent↗