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Biomedical subjects

M Rahman

Publications and source records attributed to M Rahman.

At least 271 records · Page 15Linked to original sources
PubMed1981

Outbreak of Streptococcus pyogenes infections in a geriatric hospital and control by mass treatment.

Two outbreaks of Streptococcus pyogenes infection occurred in a geriatric hospital, the first involving one ward only, the second a few weeks later, affecting two. Altogether 17 patients and 6 members of staff were carriers or were infected. All strains were indistinguishable.Extensive investigation of the environment and screening of 120 staff and patients did not reveal a common source. The usual methods of isolation and treatment of cases or carriers and swabbing of contacts failed to stop the outbreak, but 'mass treatment' of all 32 patients in those wards was successful.

Aged↗
PubMed1981

Stool electrolyte content and purging rates in diarrhea caused by rotavirus, enterotoxigenic E. coli, and V. cholerae in children.

One hundred twenty children below 5 years of age with diarrhea caused by Vibrio cholerae, enterotoxigenic Escherichia coli, or rotavirus were studied for stool electrolyte composition and purging rates. The mean purging rate in cholera was 60.1 ml, in ETEC 39.2 ml, and in rotavirus infection 31.4 ml/kg/8 hour. The mean stool sodium concentration in cholera was 88.9 mMol/L, in ETEC 53.7 mMol/L, and in rotavirus infection 37.2 mMol/L. Stool potassium concentration did not show much variation, Mean CO2 concentration in rotavirus infection was 6 mMol/L, significantly lower than in cholera and in ETEC diarrhea. In cholera, stool sodium concentration increased significantly with increase in purging rates; the same was not true in rotavirus and ETEC diarrhea. These differences are considered important factors in formulating replacement therapy in diarrhea.

Child, Preschool↗
PubMed1981

DDT-susceptibility status of malaria vector Anopheles balabacensis balabacensis Baisas (Diptera : Culicidae) in Bangladesh.

DDT-susceptibility tests on Anopheles balabacensis balabacensis Baisas carried out during several years especially during 1979 and 1980 in Sylhet district have been reported. The LC50 value for 1980 was found to be 0.88 +/- S.E. 0.02 showing 2.38 fold increase of tolerance from 1970 (LC50 = 0.37 +/- S.E. 0.07). The species is still found to be susceptible to DDT in Bangladesh. The implication of the use of DDT in controlling malaria due to this species is also discussed.

Animals↗
PubMed1981

Diagnosing thrush.

Explore the source record for details and available documents.

Candida albicans↗
PubMed1980

Oral contraceptives and family health in rural Bangladesh.

A case-control survey of mothers was undertaken in rural Bangladesh to assess the health problems of oral contraceptive users compared with two groups of nonusers. The complaint most often reported was weakness--more than 80% of all women surveyed. Significantly more pill users than nonusers reported experiencing dizziness and eye problems. However, only one fifth of dizziness complaints among pill users could be attributed to the pill. Although more pill users reported a decrease in lactation, a greater problem among the control group was total cessation of lactation related to a subsequent pregnancy. Therefore, in this context the pill may postpone weaning more often than it reduces lactation. That few women choose to use oral contraceptives in the early postpartum period, when a reduction in breast milk would be most hazardous to the child, contributes to this favorable balance. The attitude toward early termination of pregnancy was positive for 61% of pill users and 34% of nonusers. It is likely that abortion services would be favorably received in this traditional society.

Abortion, Induced↗
PubMed1980

Epidemiology and causes of death among children in a rural area of Bangladesh.

From a longitudinal surveillance programme among a rural Bangladesh population of 260,000, the epidemiology and causes of child death (under age 5) over 3 years (1975-1977) were analyzed. The most significant causes of death were diarrhoea (watery and dysentery), tetanus, measles, fever, respiratory disease, drowning, skin disease, and other causes. Of an infant mortality rate of 142.6/1000 live births, neonatal tetanus (37.4/1000), diarrhoea (19.6/1000), and respiratory disease (10.4/1000) were the most significant identifiable causes. Many infant deaths (62.2/1000) were unidentified, taking place during the neonatal (1-28 days) period. The 1-4 year mortality averaged 34.3/1 000. Diarrhoea (15.1/1 000), measles (4.5/1 000), fever (2.9/1 000) and respiratory disease (1.6/1 000) accounted for most 1-4 year deaths. Mortality trends over the past 10 years showed sharp temporary fluctuations in response to 2 disasters but no definitive long-term trend. Most causes of death displayed seasonal fluctuation, and sex differentials were marked with female deaths exceeding male deaths for all ages after the neonatal period. Malnourished children from low socioeconomic status families had higher mortality rates than their better nourished and wealthier counterparts. Overall, the data suggest that the delivery of a few basic health measures (oral hydration and immunization) could result in substantial reduction of under 5 mortality.

Age Factors↗
PubMed1980

Smallpox surveillance in Bangladesh: I - Development of surveillance containment strategy.

A major epidemic of Variola major with an estimated 90 000 cases and 18 000 deaths occurred in Bangladesh in 1972. During a 3-year period methods of active surveillance (market search, outbreak investigation, and house-to-house search) were developed to supplement the passive reporting system. The percentage of smallpox cases detected increased from 11.8% in 1972 to 83% in 1975. Together with the implementation of improved methods of outbreak control, smallpox transmission was interrupted in October 1975.

Bangladesh↗
PubMed1980

Genes and enzymes of lysine catabolism in Pseudomonas aeruginosa.

Pseudomonas aeruginosa strain PAO1 cannot utilize L-lysine effectively as a carbon source for growth but grows on cadaverine and glutarate. Strains PAO1 and PAO1632 (Hut-Ami-) have low activities for L-lysine uptake and for L-lysine decarboxylase but both strains gave rise to mutants that grew well on L-lysine. Strain PAO2087, isolated from PAO1, had an active L-lysine uptake system and an inducible L-lysine decarboxylase. Strain PAO2070, isolated from strain PAO1632, had an active L-lysine uptake system and a constitutive L-lysine decarboxylase. We suggest that the genetic defect of strain PAO1 (and PAO1632) that prevents growth of L-lysine is in a regulatory gene controlling the expression of linked genes for L-lysine permease and L-lysine decarboxylase. Mutants unable to utilize L-lysine as a carbon source, isolated from strain PAO2070, exhibited four distinct growth phenotypes. Transductional analysis showed that the genetic defects of these mutants could be distinguished from each other and from that of strain PAO1. Group I mutants, unable to utilize glutarate, formed a single transduction linkage group and were mapped at about 20 min on the chromosome. The mutations of groups II, III and IV appeared to be in separate but linked genes. The group II mutants had no detectable L-lysine decarboxylase activity and the gene locus was mapped by interrupted mating in the 50 to 60 min region of the chromosome. The group III mutants possessed all the early enzymes of the L-lysine decarboxylase pathway and lacked only an active L-lysine uptake system.

Cadaverine↗
PubMed1980

The catabolism of arginine by Pseudomonas aeruginosa.

Mutants isolated from Pseudomonas aeruginosa strain PAO1632 (Hut-Ami) were unable to utilize L-arginine or L-ornithine as the carbon source for growth. Arginine deiminase (AD), catabolic ornithine carbamoyltransferase (cOTC) and N2-acetylornithine 5-aminotransferase (ACOAT) were present in the mutants but these enzymes were not induced to higher levels by exogenous L-arginine. One group of mutants could utilize L-ornithine but not L-arginine and in these strains L-arginine induced the synthesis of ACOAT but not AD or cOTC. The mutations of the arginine utilization-negative mutants were all in genes of the same transductional linkage group and mapped in the 45 to 50 min region of the chromosome. Revertants isolated on L-arginine or L-ornithine plates were derepressed for the synthesis of ACOAT. It is suggested that L-arginine is normally catabolized by the wild-type strain via the arginine deiminase pathway and requires a threshold level of ACOAT. The regulatory factors controlling the functioning of the divergent arginine deiminase and arginine carboxylase pathways are discussed.

Arginine↗
PubMed1980

Sensitivities of clinically significant organisms to four cephalosporins, ampicillin and mecillinam.

Specimens received at a district laboratory over a period of 4 months were investigated for determination of the sensitivities of common pathogens to 4 cephalosporins, ampicillin and mecillinam. A total of 1035 freshly isolated clinically significant organisms was studied. When sensitivities of all pathogens were considered, the majority were found to be resistant to ampicillin and mecillinam and sensitive to the cephalosporins. Sensitivity figures changed considerably when individual groups of organisms were considered. The great majority of urinary pathogens were sensitive to mecillinam, but not to ampicillin. This pattern was reversed when respiratory pathogens were considered. Only a few pathogens from wound swabs were sensitive to either ampicillin or mecillinam. All the cephalosporins tested showed much wider spectrum of activities. Of all antibiotics tested, only cefoxitin was active against the vast majority of Bacteroides spp. These findings are discussed in relation to the clinical uses of these antibiotics.

Amdinocillin↗