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Biomedical subjects

M Popescu

Publications and source records attributed to M Popescu.

207 records · Page 12Linked to original sources

[Pulmonary hamartomas--apropos 3 clinical cases].

The study starts with presentation of present day knowledge of the disease. Its features are predominantly X-ray images consisting mainly in a round or ovular, usually solitary formation ("coin lesion"). The clinical expression of the disease is usually very discrete, the general state unmodified. The X-ray evidencing follows a routine examination. 3 cases of personal observations are presented. All cases were solved by surgery, by removal of tumour. Etiology is fixed by histological examination of surgery specimen. All aspects risen by the differential diagnosis are largely discussed focusing on lung granuloma (e.g. tuberculoma) lung abscess, limited pneumonia, lipoid pneumonia a.o. Hamartomas are of mesenchymal origin, they are not considered just as tumours but very similar to "tumour-like", without invasive evolution.

Adult↗

Ultrastructural modifications in mice spleen after "Imunotim' treatment.

Imunotim, a polypeptidic extract from bovine thymus, induces the appearance of barrier cells in the spleen; these cells form a syncytial network and play an important role in blood cleaning. They are of fibroblastic origin. The cytoplasm of the cells in the network is dense and contains vesicles that seem to be detached from the nucleolemma. The nuclei are of small sizes. Cells (maybe lymphocytes) in different stages of disintegration can be seen in the network.

Animals↗

[Ocular lesions due to plant foreign bodies].

The results of a survey done during the period 1988-1993, regarding the cases of ocular lesions due to vegetal foreign bodies, are presented in 51.1% of the 156 cases involved patients over 50-years-old, especially from country-side, originating in accidents during agricultural labour (79.2%). The main clinical forms of the ocular lesions as well as the nature of the vegetal foreign bodies are described. Some rare clinical aspects, involving toxic-allergic mechanisms of the ocular lesions are also mentioned. Three observations of corneal ulcerations due to vegetal foreign bodies are presented, the therapeutical methods and the evolution of visual acuity during hospitalization are also described.

Accidents, Home↗

Histochemical demonstration of folic acid metabolism, some lysosomal activities and NADH2-cytochrome-C-reductase in corpora mammillaria in the ageing process.

In bovine corpora mammillaria of young animals, a folic acid positive reaction was found in the neurons and in the neuroglia, in parallel with high dihydrofolate-reductase activity in the nerve cells. In old animals, folate and lysosome enzymes were different in the lateral and in medial nucleus, the highest amount being observed in the lateral nucleus; in the glial cells the lysosomal enzymes increased and in the nerve cells the concentration of folic acid increased. In the medial nucleus only relatively few enzyme modifications in the process of senescence were noticed.

Aging↗

Disseminated Langerhans cell histiocytosis: a case report with a light microscopic and ultrastructural study.

A case of disseminated Langerhans cell histiocytosis (L.C.H.) in a 9 month-old boy is reported. The clinical picture was characterized by severe multivisceral involvement with cutaneous and bone lesions. Histological examination of the skin biopsy revealed diffuse infiltration of large mononucleated histiocytes admixed with a small number of inflammatory cells. Ultrastructural examination confirmed the Langerhans cell (L.C.) phenotype by showing intracytoplasmic Birbeck granules in the proliferating histiocytes. We report the histological and ultrastructural characteristics of our case and review the diagnostic features of L.C.H. in the light of the criteria established by the Writing Group of the Histiocytic Society in 1987.

Histiocytosis, Langerhans-Cell↗

[The anatomico-radio-clinical forms of onset in pulmonary tuberculosis].

The aim of the study was to analyze the frequency of various radio-clinical forms of onset in newly discovered TB cases, in the area of the Sibiu dispensary on a period of 3 years (1992-1994). In the 327 cases included in the study, there was an equal sex ratio, with a symptomatic period of at least 3 months before the diagnosis. There was an increased percentage of unilateral cavitary forms, with an equal distribution in city and rural area. The severe forms were more frequent in villages and in male patients. The young patients (under 24) had mostly cavitary forms. The cavitary forms were more frequently associated with other illnesses than the caseous forms.

Adult↗