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Biomedical subjects

M Popescu

Publications and source records attributed to M Popescu.

At least 181 records · Page 10Linked to original sources
PubMedDate not supplied

[Possibilities of evaluation of the risk of tubercular infection in children and adolescents].

Two indicators are of primary importance in the assessing the tuberculous endemia in a determined area: the prevalence of bacilliferic sources, especially of those that have been confirmed by bacteriological examinations (bacterioscopy), and the annual incidence of the tuberculous infection (the real infection risk). Possibilities are described, and examples provided, for approximation of the incidence of the tuberculous infection through: a) conversion index; b) the ratio between the prevalence of the tuberculous infection and the median tested age; c) the Styble-Meijer-Sutherland logarithmic ecuation; d) the nomogram variant with tables B and C established by Styblo-Meijer-Sutherland; e) the R. Narain graphic methods. For those countries in which BCG vaccination is practiced on an extensive scale the authors suggest the incidence risk indice could also be calculated, for supra-infection, which can be correlated and completed by the incidence (risk) of infection.

Adolescent↗
PubMedDate not supplied

[Correlations between conventional allergometry and the Palmer types in interpretation of tuberculin skin tests].

In view of differentiating post-vaccinal allergy from that developing after tuberculosis infection, the authors have investigated comparatively intradermal-reactions to tuberculin according to classical allergometry, and to the 4 types described by Palmer-Edwards in a group of 1549 students and 211 patients. All the subjects were tested with 2 units of PPD IC 65. It was noted that the type I and II Palmer reactions corresponded, in the majority of the cases, to intense, or hyperergic ID reactions, while the types III and IV of Palmer corresponded to slightly positive, or to negative ID reactions. The presence of the post-vaccinal scar does not appear to influence significantly the type of the reaction, but the presence of active specific lesions is accompanied by reactions of type I and II of the Palmer classification. It is concluded that although the Palmer types do not allow to make a clear differentiation between the two variants of allergy they provide however useful indications for the interpretation of IDR in a more sophisticated manner, as compared with the conventional allergometry.

Adolescent↗
PubMedDate not supplied

[Tuberculosis in the industrial environment. Epidemiological aspects and preventive measures].

An analysis is made of the tuberculous endemia in several of the most important industrial branches over the last years, as compared with the endemy outside the industrial environment. Although the global morbidity through tuberculosis in industrial enterprises has declined to approximately one half of the initial values (considering the year 1975 as the basis), it is still above the level in the territory. The gap between the two curves, much wider at the beginning of the interval, has narrowed consistently with time. The factors are discussed, that may determine this relative morbidity, and the necessary measures for their neutralization. The necessity for a close cooperation is stressed, between the enterprise physician and the pneumologist (or phthisiologist) from the territorial polyclinic.

Adolescent↗
PubMedDate not supplied

Circadian periodicity of the results of frequently used laboratory tests in elderly subjects.

The circadian rhythms of twenty-one chemical serum parameters (albumin, alkaline phosphatase, calcium, carbon dioxide content, chloride, cholesterol, creatine phosphokinase (CPK), creatinine, glucose, glutamic-oxalacetic transaminase (GOT), gamma glutamyl transferase (Gamma--GT), lactate dehydrogenase (LDH), inorganic phosphorus, iron, potassium, total bilirubin, total protein, sodium, triglycerides, urea nitrogen, uric acid) and of urinary volume and oral temperature were studied, in October 1981, in a group of 49 elderly subjects (23 men, 73 +/- 6 years of age, and 26 women, 77 +/- 8 years of age) institutionalized at the Berceni Hospital for the aged. Statistically significant circadian rhythms as a group phenomenon were found in all functions except alkaline phosphatase, GOT, and LDH. The timing and the extent of these rhythms are presented. The circadian time structure of body chemistry appears well maintained in old age. Some circadian rhythms show a large enough amplitude to require the establishment of time qualified reference ("normal") ranges (e.g. serum iron). In most others, the circadian amplitudes are small and at present of little or no diagnostic importance. They are, however, of physiologic and pathophysiologic interest indicating an intricate time sequence of metabolic events in the human body.

Age Factors↗
PubMedDate not supplied

Circadian and circannual variations in plasma immunoreactive insulin (IRI) and C-peptide concentrations in elderly subjects.

Groups of 49-51 elderly men and women 77 +/- 8 years of age, institutionalized at the Berceni Clinical Hospital, Bucharest, Romania, were studied over a 24 hour span in spring, summer, fall and winter. All subjects followed a diurnal activity pattern with rest at night and ate three meals per day with breakfast at about 08:30, lunch at about 13:00, dinner at 18:30. The meals were similar, although not identical for all subjects during all seasons. On each day of sampling, blood was collected at four hourly intervals over a 24 hrs span. Immunoreactive insulin (IRI) and C-peptide were determined in plasma and glucose (during fall and winter only) in serum. Circadian variations of all three parameters were found and the rhythm parameters were determined statistically by cosinor analysis. The acrophases of the circadian rhythm of IRI and C-peptide were the same during all four seasons. The circadian acrophase of plasma IRI and C-peptide precedes that of serum glucose. The circadian mean concentrations of IRI and C-peptide show a circannual variation with higher values in winter and fall than in spring and summer for plasma insulin and with higher values for summer and fall than in spring for C-peptide. Sex differences in IRI and C-peptide concentrations with higher values in men are manifested during certain circadian and circannual stages but not during others.

Age Factors↗