Search PubMed⌕ Search

Biomedical subjects

M Okabe

Publications and source records attributed to M Okabe.

At least 487 records · Page 27Linked to original sources

Combined effect of cyclocytidine and lentinan of spontaneous mammary tumors in mice.

Cytotoxic cytidine analog, cyclocytidine, and antitumor immunopotentiator, lentinan, offered an opportunity of testing the effect of combined modality of cytocidal agent and immunopotentiator on spontaneous mammary tumors of mice. Lentinan did not improve the therapeutic effect of cyclocytidine; it only prevented the early toxic death of mice due to cyclocytidine in one strain of mice but not in the other strain.

Animals↗

Effect of Nocardia and Mycobacterium cell-wall skeleton on autochthonous tumor grafts.

Cell-wall skeleton of Nocardia rubra and of Mycobacterium bovis BCG in the oil-attached form, when injected mixes with autografts of spontaneous mammary adenocarcinoma or of methylcholanthrene-induced sarcoma of mice, suppresses the growth of tumor autografts to a demonstrate extent. The BCG whole cell wall showed no effect. The local destruction of tumor autografts did not induce recognizable systemic immunity to the respective tumors. These findings are commended upon from immunological and chemical points of view.

Adenocarcinoma↗