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Biomedical subjects

M Negrevergne

Publications and source records attributed to M Negrevergne.

14 recordsLinked to original sources

The prognostic value of the stapedius reflex in peripheral facial palsy.

Stapedius reflex can provide useful prognostic information in FPs when the middle ear is normal. Its preservation may have a favorable significance in partial FP and Bell's palsy. Its loss, even though less reliable, can also have some value as an indicator for a poor prognosis in patients with total and herpes zoster FPs. Most importantly, our findings have shown that the SR alone is not sufficient to be of prognostic value, but is useful if combined with other clinical parameters and electrical responses.

Adolescent

Extracochlear implants.

A unichannel extracochlear implant designed and made in our laboratory was tried on several patients. Results to date are very similar in all cases. Very rudimentary auditory information is provided, which can help totally deaf patients.

Cochlear Implants

Temporary tinnitus suppression in man through electrical stimulation of the cochlea.

While investigating the possibilities of electrically induced hearing in cases of profound deafness, we observed that very often an appropriate stimulation of the cochlea could result in tinnitus cancellation. We present here a progress report on that phenomenon, including 15 subjects. Such a cancellation was restricted to tinnitus subjectively localized in the ear under test, we observed no effect on noises localized in the other ear, or centrally. This suppression occurred so long as the cochlea was stimulated and stopped when the stimulation ceased. This phenomenon was very reproducible and did not seem to affect simultaneous normal acoustic hearing. It is hypothesized that this phenomenon acts through an inhibition of abnormal activity of sensorineural elements of the electrically stimulated cochlea.

Cochlea

[Electrocochleography and topographic diagnosis].

We present a group of 50 patients with retrocochlear pathology, divided on 41 (82 per 100) non tumoral and 9 (18 per 100) tumoral: 8 cerebello-pontine angle meningiomas and 1 intracranial cholesteatoma. The retrocochlear diagnosis of the pathology is assessed by the results of the audiovestibular explorations, specially the electrophysiology (early auditory evoked response, electrocochleography). The neuroradiologic explorations (TAC, MNR) define the tumoral or non tumoral nature of the pathology. We review some technical aspects of the common electrocochleographic practice, as actually is realised by the Bordeaux group; also, the different parameters of a retrocochlear pathologic response. In this group, the electrocochleography was necessary on 64 per 100 of the cases to obtain an electrophysiologic retrocochlear diagnostic.

Acoustic Impedance Tests

[Stapedial reflex in nontumor retrocochlear pathology].

The authors study the different parameters of the stapedius reflex on a 55 patients group with retrocochlear and non tumoral diagnostic is assess by electrophysiologic (BERA, Electrocochleography) and neuroradiologic explorations (TAC), Meato-cisternography, NMR). We realise an comparative study between the results of this group and the results of 2 other groups (98 acoustic neuromas and 104 endocochlear diseases). The test has a moderate sensibility and none specificity in this kind of pathology, because the high percent of false negative (30%), and the positivity on 95% of acoustic neuromas and on 74% of endocochlear diseases.

Acoustic Impedance Tests

Electrical stimulation of the cochlea in man: hearing induction and tinnitus suppression.

Sensations induced by electrical stimulation of the cochlea in humans through a promontory or a round window electrode were studied in sixteen subjects. All the patients had total or severe hearing losses. Comparison of the results with the recordings of cochlear potentials gave valuable information in all cases about the site and degree of the disorder. The data on electrically induced auditory sensation are very similar to the general findings of other authors and support the attempts of rehabilitation of the deaf by this means. The most important result reported here is the cancellation of tinnitus during stimulation by positive pulses in most cases, without affecting simultaneous acoustical or electrical hearing. This phenomenon is very reliable and could lead to very important future developments.

Adult