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Biomedical subjects

M Nadji

Publications and source records attributed to M Nadji.

112 records · Page 7Linked to original sources

Fine needle aspiration cytology in gynecologic oncology. II. Morphologic aspects.

This study was based on the evaluation of 140 fine-needle spirations from gynecologic lesion. Cytologic criteria for the diagnosis of benign and malignant lesions and cellular changes due to irradiation and chemotherapy are presented. For accurate evaluation of fine-needle aspiration specimens from the pelvis, the exact location of the sampling must be known, clinical data must be available, and the patholgist must have an intimate knowledge of anatomy, histology and pathology of benign and malignant lesions in this area. Fine-needle aspiration cytology provided a high degree of accuracy in the diagnosis of gynecologic lesions.

Adenocarcinoma↗

Fine needle aspiration cytology in gynecologic oncology. I. Clinical aspects.

One hundred forty fine needle aspirations were performed on 124 patients with a variety of gynecologic conditions. The primary goal of this study was to investigate the adequacy of this technique in the primary diagnosis of pelvic masses and in the detection of persistent or recurrent gynecologic malignancies following irradiation or chemotherapy. In this, the first of two articles, the clinical aspects of the procedure, including clinical indications and the different approaches and pelvic sites of fine needle aspiration, are discussed. The simplicity and lack of complications of the method, combined with a high degree of accuracy in predicting the histologic picture of various lesions, merit wider application of this technique as a reliable diagnostic tool in gynecologic oncology.

Abdominal Neoplasms↗

The potential value of immunoperoxidase techniques in diagnostic cytology.

A slightly modified immunoperoxidase method was developed in our laboratory and applied to a variety of aspiration and exfoliative cytologic material. Our aims were: (1) to explore the applicability of the immunoperoxidase procedure to diagnostic cytology, (2) to attempt to define the histogenesis of neoplastic cells when morphology alone proved insufficient, and (3) to investigate the possibility of differentiating reactive from neoplastic lymphoreticular disorders by studying their immunoglobulin patterns. Our findings indicate that the immunoperoxidase technique is applicable to cytologic material. The simplicity of the procedure, combined with its high sensitivity and excellent morphology, merits wider application of this technique to routine diagnostic cytology.

Acid Phosphatase↗

Aspiration cytology of ovarian neoplasms. A review.

Unlike other gynecologic tumors, which are accessible to inspection and biopsy, ovarian neoplasms are located within the pelvis or abdomen and are reachable only by laparoscopy or exploratory laparotomy. Because of its simplicity, fine needle aspiration cytology may be used as an alternative to surgical procedures. However, because of the great variety of tumor types in the ovary, cytologic interpretation of aspirates from that organ represents one of the most challenging fields in diagnostic cytology. Nevertheless, as clinicians become more experienced in using this technique and pathologists gain confidence in their ability to evaluate samples correctly, aspiration cytology may prove to be one of the most valuable and acceptable tools in the diagnosis of tumors of the female pelvis.

Biopsy, Needle↗