Biomedical subjects
Publications and source records attributed to M Moschos.
This paper presents the case study of six patients suffering from acute bilateral optic neuritis simultaneously manifested in both eyes. The clinical picture and the full laboratory investigation failed to establish a real cause of the disease. Finally the lack of general neurological symptoms and the good prognosis of the disease after a two year follow-up is stressed.
C-wave and ERG records have been taken from patients with juvenile macular degeneration, cone dysfunction syndrome, non exudative macular degeneration and from patients who have taken hydroxychloroquine for more than a year. The study of these recordings showed that in juvenile macular degeneration the involved area might be larger than ophthalmoscopically visible. In cone dysfunction syndrome the prolonged latence implicit time can serve as a further diagnostic sign of the disease. In non exudative macular degeneration there is more extensive R.P.E. involvement than usually believed and finally in hydroxychloroquine retinopathy, the C-wave is a better criterion to monitor the disease than ERG.
Extracapsular extraction with anterior-chamber lens implantation is a method which has a place in cataract surgery. We discuss 60 cases of cataract operated on by this method and its advantages. We had good results in cases without glaucoma, keratopathy, or diabetes mellitus, and depending on the ease with which a posterior capsulotomy was done, where this was imperative, without the risks of the YAG laser capsulotomy.
Disturbances of the oscillatory potentials of the ERG are examined in diabetic patients with and without vascular lesions of the retina. More specifically, the changes of the oscillatory potentials are investigated in relation to the manifestation and evolution of diabetic retinopathy and neovascularization of the optic disk and the retina. Particular stress is laid on the direct relation between the disturbances of the oscillatory potentials and the occurrence of neovascularization, as well as on the prognostic significance of these disturbances.
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A case of serious endophthalmitis two years after a Lincoff-Custodis procedure is presented. Even after the removal of the silastic sponge a phthisis bulbi appeared with loss of vision. Such a catastrophic complication is possible even after a period as long as two years if the appropriate therapeutic measures are not taken.
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The present investigation analyzes the results of the ERG and VER studies after argon-laser photocoagulation of the papillomacular region and after panretinal argon-laser photocoagulation. The author stresses the possibility of photocoagulation of the papillomacular region without risk of damaging the papillomacular fibers as well as the observation that panretinal photocoagulation performed under identical parameters does not affect electric activity (and consequently the anatomical integrity of the retina) to the same extent in different eyes. The ERG could thus be used for an objective assessment of the degree of adequacy of panretinal photocoagulation.
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In this experimental investigation the authors studied the electro-retinographic alterations and the histological lesions of the retina of rabbits following the intravitreal injection of different doses of gentamicin.
In this work seven cases with epithelial cyst of the iris resulting from trauma or cataract surgery were studied and treated by Argon laser photocoagulation. The authors analyse theirs results stressing the fact that no alteration of the lens or the cornea has been provoked after a follow-up of three years.
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In this experimental study the authors studied the Eclectroretinographic alterations and the histological lesions after the introduction of foreign bodies of iron and copper into the vitreous body of eyes of rabbits. The ERG alterations depend on the kind of the intraocular foreign body and on the size and the time it remained into the eye. These alterations are characterised either by a parallel diminution of the a and b wave of the ERG, or by an increase of the a wave while the b wave becomes flat. From the histological studies it was found that the iron is deposited into the nucleus and the cytoplasm in the form of granules, while the copper causes a violent inflammatory reaction and is deposited extracellularly.
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Cyclocryopexy constitutes a method for the therapy of absolute or hemorrhagic painful glaucoma. The authors describe its technique, its indications and the postoperative results obtained in 38 patients, from which they make appropriate conclusions.