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Biomedical subjects

M Moschos

Publications and source records attributed to M Moschos.

At least 37 records · Page 2Linked to original sources
PubMed1992

C wave of electroretinogram and visual evoked response in optic neuritis due to demyelinating diseases.

In 21 consecutive cases with unilateral optic neuritis due to demyelinating disease, ERG, C wave of ERG and VER were recorded and studied in both eyes. Also 8 cases suffering from optic atrophy due to trauma or glaucoma were included. The analysis of data shows that the C-wave is significantly diminished in both eyes, namely the affected and the sound, in the cases of optic neuritis. Also in comparison to VER, C wave has a comparative probability in diagnosing optic neuritis due to demyelinating disease. The C wave of ERG is normal in the cases of optic atrophy. The mechanism of C wave involvement during the course of demyelinating disease may be related with an abnormality of the ionic homeostasis of the subretinal space.

Adolescent↗
PubMed1990

C wave study in optic neuritis due to demyelinating disease.

The C wave was recorded from 20 eyes suffering from neuritis due to demyelinating disease and in 5 eyes showing optic atrophy due to trauma or to increased intracranial pressure. Our results show that in cases with optic neuritis the C wave amplitude was clearly lower than normal. It is interesting that in the other 'healthy', at least clinically, eye the C wave was subnormal too. On the contrary, in the eyes with optic atrophy the C wave was normal. These findings are against the possibility of an efferent neuronal pathway involvement, which influences the level of the retinal pigment epithelium, and support the view of its involvement during the course of the demyelinating disease that causes the optic neuritis.

Adolescent↗
PubMed1990

ERG and electron microscopic findings after intravitreal use of aminoglycosides.

The electroretinographic (ERG) changes and the retinal lesions shown by electron microscopy were studied in rabbits after intravitreal use of amikacin and tobramycin. We studied 40 eyes of 20 rabbits in which different doses ranging from 250 micrograms to 1000 micrograms of aminoglycosides were injected into the vitreous cavity. Tobramycin, and to some extent amikacin, were toxic to the retina even in doses of 500 micrograms as shown by ERG changes. The pathologic retinal lesions shown by electron microscopy were characterized by membranous inclusions in the retinal pigment epithelium, tumefaction of the photoreceptors, and partial disorganization of the inner layers. In doses of 250 micrograms or less, these two antibiotics seem to be nontoxic after a follow-up of three months.

Amikacin↗
PubMed1989

Acute bilateral optic neuritis.

This paper presents the case study of six patients suffering from acute bilateral optic neuritis simultaneously manifested in both eyes. The clinical picture and the full laboratory investigation failed to establish a real cause of the disease. Finally the lack of general neurological symptoms and the good prognosis of the disease after a two year follow-up is stressed.

Acute Disease↗
PubMed1989

[C-wave changes in macular diseases].

C-wave and ERG records have been taken from patients with juvenile macular degeneration, cone dysfunction syndrome, non exudative macular degeneration and from patients who have taken hydroxychloroquine for more than a year. The study of these recordings showed that in juvenile macular degeneration the involved area might be larger than ophthalmoscopically visible. In cone dysfunction syndrome the prolonged latence implicit time can serve as a further diagnostic sign of the disease. In non exudative macular degeneration there is more extensive R.P.E. involvement than usually believed and finally in hydroxychloroquine retinopathy, the C-wave is a better criterion to monitor the disease than ERG.

Adolescent↗
PubMed1988

Extracapsular extraction and anterior-chamber flexible lens implantation.

Extracapsular extraction with anterior-chamber lens implantation is a method which has a place in cataract surgery. We discuss 60 cases of cataract operated on by this method and its advantages. We had good results in cases without glaucoma, keratopathy, or diabetes mellitus, and depending on the ease with which a posterior capsulotomy was done, where this was imperative, without the risks of the YAG laser capsulotomy.

Aged↗
PubMed1987

Changes of oscillatory potentials of the ERG in diabetic retinopathy.

Disturbances of the oscillatory potentials of the ERG are examined in diabetic patients with and without vascular lesions of the retina. More specifically, the changes of the oscillatory potentials are investigated in relation to the manifestation and evolution of diabetic retinopathy and neovascularization of the optic disk and the retina. Particular stress is laid on the direct relation between the disturbances of the oscillatory potentials and the occurrence of neovascularization, as well as on the prognostic significance of these disturbances.

Aneurysm↗
PubMed1983

A severe endophthalmitis after Lincoff-Custodis procedure.

A case of serious endophthalmitis two years after a Lincoff-Custodis procedure is presented. Even after the removal of the silastic sponge a phthisis bulbi appeared with loss of vision. Such a catastrophic complication is possible even after a period as long as two years if the appropriate therapeutic measures are not taken.

Endophthalmitis↗
PubMed1982

ERG and VER findings after laser photocoagulation of the retina.

The present investigation analyzes the results of the ERG and VER studies after argon-laser photocoagulation of the papillomacular region and after panretinal argon-laser photocoagulation. The author stresses the possibility of photocoagulation of the papillomacular region without risk of damaging the papillomacular fibers as well as the observation that panretinal photocoagulation performed under identical parameters does not affect electric activity (and consequently the anatomical integrity of the retina) to the same extent in different eyes. The ERG could thus be used for an objective assessment of the degree of adequacy of panretinal photocoagulation.

Choroid Neoplasms↗
PubMed1977

[Electroretinographic changes in experimental metalloses].

In this experimental study the authors studied the Eclectroretinographic alterations and the histological lesions after the introduction of foreign bodies of iron and copper into the vitreous body of eyes of rabbits. The ERG alterations depend on the kind of the intraocular foreign body and on the size and the time it remained into the eye. These alterations are characterised either by a parallel diminution of the a and b wave of the ERG, or by an increase of the a wave while the b wave becomes flat. From the histological studies it was found that the iron is deposited into the nucleus and the cytoplasm in the form of granules, while the copper causes a violent inflammatory reaction and is deposited extracellularly.

Animals↗