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Biomedical subjects

M Monti

Publications and source records attributed to M Monti.

At least 235 records · Page 13Linked to original sources
PubMed1984

Heat production in human blood lymphocytes. A methodological study.

Heat production rates (thermal power) in peripheral blood lymphocytes from healthy subjects were determined under some defined experimental conditions in an attempt to establish by microcalorimetry a basal metabolic reference range for lymphocytes in the non-activated state. The effects of cell isolation method, the presence of other types of blood cells, cell concentration, temperature, pH and type of suspension medium on the rate of heat production by lymphocytes were evaluated. The results indicate that microcalorimetry is suitable for monitoring the metabolism of these cells with good precision in the physiological range of cell concentration.

Basal Metabolism↗
PubMed1983

[Deep venous thrombosis of the upper extremities: occurrence, etiology and prognosis].

Incidence, clinical findings, etiology and evolution of 25 cases of deep venous thrombosis of the upper extremity are evaluated in a group of 23 in- and outpatients. The incidence of the disease represents less than 6% of all deep venous thromboses. The most frequent etiology among outpatients was "primary" deep venous thrombosis. The percentage of pulmonary embolism was 8%. The prognosis is favourable in 90% of cases.

Arm↗
PubMed1983

The avidin-biotin peroxidase complex (ABCPx)/in skin immunoelectron microscopy.

The interaction between avidin and biotin can be exploited in immunoperoxidase techniques in three main way: the labeled avidin-biotin technique (LAB); the bridge avidin-biotin technique (BRAB); the performed avidin-biotin complex (ABCPx). In a comparative study of these three methods and the peroxidase antiperoxidase method using serial dilutions of antinuclear positive serum, the ABCPx method yielded the most intense staining. For this reason, the ABCPx method has been applied in immunoelectron microscopy (IEM) techniques on normal and pathological skin employing monoclonal OKT4, OKT6, OKT8 antibodies to detect target membrane antigens. The authors notes that the ABCPx method allows strong staining both in normal and pathological skin and improves tissue preservation.

Antigens↗
PubMed1983

Small-bowel involvement in dermatitis herpetiformis and in linear-IgA bullous dermatosis.

In 23 patients with dermatitis herpetiformis (DH) and five patients with linear-IgA bullous dermatosis (BD), we evaluated the occurrence of histologic jejunal changes and small-bowel function abnormalities. None of the patients showed clinical signs or symptoms of malabsorption. Morphological jejunal changes consistent with gluten-sensitive enteropathy were found in 82% of DH patients and in 60% of BD patients. However, BD patients showed only mild jejunal histologic abnormalities, whereas more severe jejunal lesions were found in most patients with DH. Functional tests showed a rough correlation with the severity of the jejunal lesions, being almost completely normal in BD patients and DH patients with mild intestinal damage, whereas most of DH patients with subtotal or total villous atrophy showed abnormal d-xylose tests and folic acid assays. Lactose tolerance tests (H2 breath test and blood glucose after oral lactose load) showed no correlation with the degree of jejunal damage.

Adult↗
PubMed1983

The morphologic events of blister formation in porphyria cutanea tarda.

In porphyria cutanea tarda (PCT), the submicroscopic event causing the formation of spontaneous blisters is the appearance of membrane-limited vacuoles in the superficial dermis. These vacuoles are apparently formed through cytolysis of dermal cells and swelling of the pseudopodia of the basal cells protruding into the dermis, probably as a consequence of photochemically-induced lysosomal damage. The number and size of these vacuoles progressively increase near the cleavage area of the blisters, where their limiting membranes merge and break, giving rise to the cavity of the blister, which is formed under the basal lamina. The presence of coated vesicles along the limiting membranes as well as inside the vacuoles suggests their involvement in the transport of fluids from the damaged vessels, thus contributing to the progressive volume increase of vacuoles themselves.

Adult↗