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Biomedical subjects

M Mehta

Publications and source records attributed to M Mehta.

At least 127 records · Page 7Linked to original sources
PubMed1983

Intubation conditions after atracurium and suxamethonium.

Conditions for endotracheal intubation provided by different dose regimens of atracurium 0.4 mg kg-1 and 0.5 mg kg-1 were studied and compared with each other and with suxamethonium 1.0 mg kg-1. Intubation was attempted at 2.5, 2 min and 1.5 min following a bolus dose of atracurium, and 1 min following suxamethonium. Ease of intubation was rated excellent in 90-100% of all patients studied. Atracurium, when administered 5 min following recovery from a suxamethonium-induced block, had a significantly faster onset of neuromuscular blockade (P less than 0.01) than the onset observed following atracurium alone. Administration of atracurium 0.42 mg kg-1 3 min after an initial dose of 0.08 mg kg-1 of the drug produced a significantly more rapid onset of block when compared with a bolus dose of 0.5 mg kg-1 (P less than 0.02).

Adult↗
PubMed1979

Malignant paraganglioma of the prostate and retroperitoneum.

A case of malignant paraganglioma of the prostate, metastatic to the retroperitoneal area, is reported. The literature is reviewed and the possible origin of the disease is discussed. We believe that this is the first report of this entity of prostatic origin.

Adult↗
PubMed1979

The treatment of chronic back pain. A preliminary survey of the effect of radiofrequency denervation of the posterior vertebral joints.

Structures innervated by the dorsal primary ramus play a significant part in the genesis of chronic backache and associated leg pain. The features of this syndrome are described and compared with those in the more familiar clinical picture following intervertebral disc degeneration. However these clinical entities are seldom entirely separate and the diagnosis is often also complicated by psychosomatic factors and the consequences of previous back surgery. A technique of percutaneous facet denervation with a radiofrequency probe, although by no means successful in every case, is entirely safe and a very wothwhile procedure. It has helped many patients, who would otherwise have been disabled by pain and restricted in their activities.

Anesthesia, Local↗
PubMed1978

Alternative methods of treating pain.

The range of non-invasive methods of treatment of chronic pain which are currently available has been discussed. They fall into three categories; those dependent on counter stimulation, those which influence the higher centres and those, like acupuncture, which possibly combine both mechanisms. The empirical, but frequently successful nature of such treatments has been emphasised.

Acupuncture Therapy↗
PubMed1977

The medical treatment of secretory otitis media. A clinical trial of three commonly used regimes.

A clinical trial was undertaken to evaluate three medical treatments commonly used for chronic secretory otitis media. The treatments compared were Ephedrine nose drops, an oral antihistamine and decongestant (Dimotapp) and autoinflation of the middle ear. Changes in middle ear compliance and pressure were used as objective criteria of the efficacy of treatment in addition to changes in pure-tone threshold and to clinical assessment. Symptoms and abnormal signs tended to remit during the trial but there was no evidence from pure-tone audiometry and tympanometry that any of the treatments was beneficial. The period of observation enabled 28% of the children to avoid surgical treatment. Good and bad prognostic features are described which should help in deciding whether to manage a case conservatively or whether to proceed directly to surgery.

Brompheniramine↗
PubMed1977

Injection into the extra-arachnoid subdural space. Experience in the treatment of intractable cervical pain and in the conduct of extradural (epidural) analgesia.

The anatomy and radiological appearances of the subdural space in the cervical region are described. Recognition of this space facilitates neurolytic injections for severe cancer pain in the distribution of the cervical nerve roots. The subdural space may have significance also in explaining the extensive sensory block which follows a delayed or 'massive' lumbar extradural injection.

Analgesics↗