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Biomedical subjects

M Levesque

Publications and source records attributed to M Levesque.

At least 73 records · Page 4Linked to original sources
PubMed1989

[Zollinger-Ellison syndrome of ovarian origin. Apropos of a case with a review of the literature].

We report a case of Zollinger-Ellison syndrome due to secretory G and D cells in an ovarian mucinous cystadenoma. Surgical resection of the tumour led to disappearance of clinical symptomatology and laboratory signs. Four other cases were found in the literature. The prognosis of the Zollinger-Ellison syndrome, due to a secretory ovarian tumour, appears to be favourable after oophorectomy.

Adult↗
PubMed1989

[Echographic study of gallbladder contraction: normal and pathologic aspects. Apropos of 115 patients].

The gallbladder volume was measured on abdominal ultrasonography in 115 patients consisting of three population groups, before and after ingestion of a fatty meal and/or intravenous administration of cholecystokinin. The variation in volume, estimated as a percentage, was used to assess gallbladder contraction. The first group, consisting of 40 normal individuals without gallstones or impaired gallbladder or hepatic function, can be considered to constitute a control group. In this population, gallbladder contraction exceeded 50% in every case. The second group consisted of 40 cases of acute cholecystitis, including 30 cases with acute gallstones and 10 cases of stone-free acute cholecystitis proven surgically (7 cases) or by guided aspiration (3 cases). Gallbladder contraction was less than 15% in every case. Lastly, a third group of 35 patients with uncomplicated gallstones discovered on routine ultrasonography, demonstrated gallbladder contraction of between 10 and 85%. In this last group, 12 patients with vague gastrointestinal symptoms and gallbladder contraction less than 15% were operated: the histological results demonstrated severe lesions of chronic gallstone cholecystitis. The authors believe that absent or weak gallbladder contraction after endogenous stimulation is a supplementary sign to be taken into consideration in a context suggestive of the diagnosis of acute stone-free cholecystitis and to suggest, in the presence of gastrointestinal symptoms not directly related to the gallbladder, the hypothesis of chronic gallstone cholecystitis.

Acute Disease↗
PubMed1989

[Spontaneous intrahepatic hemorrhage: a severe complication of the Hellp syndrome. Value of early radiologic diagnosis. Apropos of a case].

One case of spontaneous hepatic hemorrhage during a severe pre-eclampsia and Hellp syndrome (hemolysis, elevated liver function tests, low platelet count) is reported. This serious complication can be detected by ultrasonography and C.T. The normal sonographic appearance of the liver must prompt a new sonographic examination as soon as possible. C.T. of the abdomen confirmes the diagnosis and delineates the lesions more precisely. It is suggested that with the availability of ultrasound and computed tomography to diagnose and stage the hepatic hemorrhage, they have a systematic indication during the Hellp syndrome.

Adult↗
PubMed1988

Correlation of laser-Doppler-velocity measurements and endothelial cell shape in a stenosed dog aorta.

Laser-Doppler-velocity measurements were carried out in an elastic 1:1 true-to-scale silicone rubber model of a dog aorta with stenosis. The model was constructed from a cast of a severely stenosed dog aorta (71% of its area). The stenosis in the dog aorta was prepared by wrapping a cotton band around the aorta. This band was tightened until the presence of a thrill or a bruit was felt distal to the band. Twelve weeks later the animal was sacrificed and a cast was prepared from the aorta. From this vascular cast, the cross-sectional area was calculated. Endothelial cell geometry and orientation was studied using computerized analysis to determine the cell area and shape index. An elastic silicone rubber model was prepared from the cast to measure the velocity profiles and to estimate the local wall shear stress. Velocity measurements were done at steady and pulsatile flow using a Newtonian aqueous-glycerol solution and a non-Newtonian blood-like fluid. From those velocity measurements the velocity gradients near the wall were determined and the shear stress calculated. The flow distal to the stenosis separates from the wall at physiological conditions. The endothelial cells are smaller and more elongated in the throat; distal to the stenosis they are larger and rounder. The shape index distribution along the stenosed aorta is correlated with the level of wall shear stress. It is shown that even low changes in the wall shear stress have an influence on the orientation of the endothelial cells.

Animals↗
PubMed1988

Radiological features in congenital erythropoietic porphyria (Gunther's disease). Report of 3 cases.

Gunther's disease or congenital erythropoietic porphyria is a rare and severe disorder comprising cutaneous and haemolytic symptoms. Photocutaneous lesions are responsible for scleroderma-like calcifications and deformities of the extremities visible on X-rays. Hemolytic manifestations lead to diffuse major osteopenia. Soft tissue calcifications of the fingers can be seen even in young patients. One case reported here is the first illustration of intracranial calcifications located on dura-mater and calvarium.

Bone Diseases, Metabolic↗
PubMed1988

[Disk hypodensity and disk herniation].

The authors report the case of a patient with a herniated lumbar disk and bacterial meningitis. CT scan showed central disk hypodensity at the hernia level, whilst full cytological and bacteriological study of the disk following surgery revealed no evidence of spondylodiscitis. The problem was thus that of consequences of "degenerative" events related to the herniation. Central or peripheral disk hypodensity must in no case be considered as specific of discitis when there is a concomitant disk herniation.

Aged↗
PubMed1987

Magnetic resonance imaging of cerebral arteriovenous malformations.

Magnetic resonance imaging (MRI) was performed in 15 patients with small to very large supratentorial arteriovenous malformations (AVMs). Unlike non-contrast infused computed tomographic (CT) scanning, MRI demonstrated the AVM in all cases. The nidus had a characteristic honeycomb appearance, and in all cases feeding arteries and deep or superficial draining veins were demonstrated without intervening bone artifact. The relationship of the AVM to surrounding cortical areas, deep nuclei, important white matter tracts, and the ventricular system was well appreciated. These characteristics make MRI useful for the diagnosis of cerebral AVMs and add to the accuracy of systems that grade operability on the basis of the angiographic demonstration of size, location, depth, arterial supply, and venous drainage. In many cases, based on the MRI appearance of the AVM and its relationship to important brain structures, the lesion can be deemed inoperable or unsuitable for other forms of treatment, making angiography unnecessary. Thus, the superior anatomical and morphological resolution of MRI, the lower false-negative rate, and the independence from x-ray and contrast material make MRI more useful than CT scanning for the diagnosis of AVMs and as an aid in the management of specific cases.

Adult↗
PubMed1987

[Reliability of the combination of ultrasonography-cystography in the study of urinary infection in children. Prospective study on 90 cases].

The authors report a prospective study concerning 90 children with a urinary tract infection, investigated for the first time by radiological and ultrasonographic techniques. Amongst these 90 children, 50 (i.e. 55% of cases) had a normal retrograde cystography and ultrasonography. These children did not have any IVU and medical surveillance proved to be sufficient. Ten patients had a normal retrograde cystography and abnormal ultrasonography. Intravenous urography carried out in these 10 cases revealed in 8 instances an abnormality of the upper urinary tract. Finally 30 children had an abnormal retrograde cystography, with reflux in 29 cases, leading to intravenous urography which yielded a pathological result in only half of the cases studied. This series confirms the central role of retrograde cystography. When it is normal, intravenous urography may be legitimately substituted by ultrasonography.

Child↗
PubMed1986

[Value of ultrasonic diagnosis in the evaluation of hip dislocation in neonates and infants. Apropos of 340 cases].

Ultrasound imaging of hip (UIH) was performed in 170 children (340 hips) with normal (193) and dysplasic (147) hips and findings compared with results of clinical and radiologic examinations. Ultrasound demonstrated 100% sensitivity in cases with abnormal clinical and radiologic finding, and 94% specificity for UIH when clinical and radiologic examinations were negative. Sensitivity and specificity of ultrasound screening (respectively 96 and 81%) were comparatively superior to those of radiography of the pelvis (83 and 78%) in relation to the clinical examinations. These findings predict further development of UIH for screening of congenital dislocation of the hips and for follow up surveillance of treated children.

Evaluation Studies as Topic↗
PubMed1985

Responses to light of retinal neurons regenerating axons into peripheral nerve grafts in the rat.

We have recorded unitary activity from axons regenerated into peripheral nerve grafts inserted into the retina of adult rats. Some retinal ganglion cells regenerating axons into these grafts had responses to light similar to those of intact retinal ganglion cells. The number of units that responded to light in these blind-ended grafts declined between 9 and 48 weeks after graft insertion. Axotomized retinal ganglion cells regenerating axons into peripheral nerve grafts thus appear, at least temporarily, to maintain or resume normal function.

Animals↗
PubMed1985

[Fatal massive intravascular coagulation during phlebography. Responsibility of epsilon-aminocaproic acid?].

The occurrence during phlebography of massive intravascular coagulation involving the inferior vena cava, the right cardiac cavities and the entire pulmonary arterial network suggested that epsilon-aminocaproic acid administered before phlebography was responsible for this complication. The mechanisms of reactions to contrast media are still poorly understood, but these reactions are known to include, in some cases, disseminated intravascular coagulation. This phenomenon was histologically demonstrated in our patient, and it may be suggested that its strong enhancement by the antifibrinolytic agent had resulted in the fatal accident. In view of the possibility of such lethal reactions, the advisability of administering epsilon-aminocaproic acid--a drug widely used in France for the prevention and treatment of contrast media reactions--should be reconsidered.

Adult↗