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Biomedical subjects

M Lato

Publications and source records attributed to M Lato.

At least 19 recordsLinked to original sources

One-year status of homeless mentally ill clients who completed a transitional residential program.

Of 228 homeless, severely persistently mentally ill clients admitted within a 5 1/2 year period to a transitional residential program, 179 (79%) remained in contact with staff for at least one year post-discharge. Housing was maintained by 141 (78%) of the clients for at least one year. Entitlements increased from admission, to discharge, to one year post-discharge. Clients maintaining contact for at least one year post-discharge were likely to have participated in two or more day treatment programs during residence. Success of the Program may be partly attributed to the staff's vigilance in maintaining post-discharge client contact.

Adult↗

Components of an effective transitional residential program for homeless mentally ill clients.

UNLABELLED: Review of clinical records of 228 former clients of a Transitional Residential PROGRAM for severely, persistently mental ill homeless persons was conducted to examine PROGRAM results for completers and noncompleters. Of the 228 clients, 110 (48.3%) completed the PROGRAM: they became psychiatrically stabilized, found secure housing, and began receiving disability pensions. Completers participated in significantly more activities than noncompleters. Psychiatric diagnosis was unrelated to successful PROGRAM completion. Individuals who left against advice had significantly fewer previous hospitalizations.

Activities of Daily Living↗

Analysis of some tryptophan and phenylalanine metabolites in urine by a straight-phase high-performance liquid chromatographic technique.

A high-performance liquid column chromatographic technique is reported for the analysis of some tryptophan and phenylalanine acid metabolites in the urine. An acidified and NaCl-saturated urine sample is loaded on to a C18-bonded silica microcolumn. After washing the microcolumn with clean and deionized water, the metabolites of interest are selectively extracted by successive elutions with organic solvents of variable polarity. Acids are eluted first and the neutral compounds with the next fraction. Basic compounds and other neutral substances of higher polarities were eliminated during the washing procedure. The chromatography was performed in the straight-phase isocratic elution mode utilizing 5-micrometers silica-gel columns loaded with a triethanolammonium perchlorate--perchloric acid aqueous solution. The separation achieved have permitted the application of the chromatographic technique to the analysis of urinary metabolites with acceptable accuracy.

Chromatography, High Pressure Liquid↗

Improved thin-layer chromatographic method for sugar separations.

A method is described for the utilization of pre-coated, non-impregnated silical gel thin layers in one- and two-dimensional separations of carbodhyrates and related compounds. Boric and phenylboronic acids were added to the organic elution systems in different concentrations and their interactions with the sugar molecules during the chromatographic process were studied. A comparison was made between solvent systems containing boric or phenylboronic acid and systems devoid of both acids as eluents. With boric acid-containing solvents the migration of some sugars was considerably inhibited, whereas phenylboronic acid produced an increase in the RF values of certain sugars. The combination of these two types of solvent in two dimensional development resulted in the clear separation of a group of mono- and disaccharides of bioclinical interest.

Carbohydrates↗

A new screening test for the diagnosis of mucopolysaccharidoses.

A simple method for the electrophoretic separation of glycosaminoglycans from untreated urine is presented. It is shown that this rapid electrophoresis on specially shaped acetate cellulose strips gives more information than other screening tests used in laboratory for discriminating between normal and pathological samples. This technique is useful particularly with low levels of glycosaminoglycans which may give false-negative responses.

Electrophoresis, Cellulose Acetate↗

Membranous glomerulonephritis in congenital syphilis.

The glomerulonephritis of congenital syphilis is thought to be immune-complex mediated. We describe a case of C. S. in whom the only manifestation was a glomerulonephritis. Immunopathogenic studies allowed the identification of treponemal antigen in glomeruli. The elution of immunoglobulins from renal tissue showed that glomerular deposits contained antitreponemal antibodies. Cryoglobulins with antitreponemal activity were also isolated from the patient's serum.

Antibodies, Bacterial↗