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Biomedical subjects

M Lanza

Publications and source records attributed to M Lanza.

59 records · Page 4Linked to original sources
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[Dyslipidemia and hyperbaric osteonecrosis in the rat].

The authors subjected 149 adult Sprague-Dawley rats to repeated experimental dives, simulated to 160 m. Histopathological examination (femurs and tibias) revealed no evidence of osteonecrosis in either normal or dyslipidaemic animals. Study of the calcium metabolism using 45Ca revealed a significant drop in the levels of free and bound calcium and in the rate of exchange between the two compartments, in the dyslipidaemic animal placed in hyperbaric conditions.

Animals↗
PubMedDate not supplied

[Kinetics of sodium thiosulfate-35S fixation and effect of some sulfur compounds on iodine-131 fixation in ray thyroid gland].

In order to invalidate or confirm the affirmation that non antithyroid sulphide molecules alter the measure of the thyroid fixation rate of iodine 131 we undertook on the rat: on one hand a kinetic study of thyroid fixation of sodium thiosulfate labelled with sulphur 35, which showed a very low captation not exceeding 0,01% of injected radioactivity; on the other hand the study of the effects of some sulphide molecules on thyroid fixation of iodine 131 in the rat: sodium thiosulfate, association of sodium thiosulfate + metalloidal sulphur + methionine, carbutamide and dimethylsulfoxyde in various kinds of dose administration and periods. None of the products used in our work conditions produced a significant decrease of the fixation rate of iodine 131. In three different experimental protocols (sulfur association and dimethylsulfoxide), we showed a significant light increase of the fixation rate.

Animals↗