[Discussion of the article by I. Huvar, et al: "Hysteroscopic resection of myomas"].
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Biomedical subjects
Publications and source records attributed to M Kudela.
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Paravaginal cysts are relatively infrequent developmental anomalies. Mostly the Gaertner's cysts are found, which arise from the remnants of the Gaertner's duct. These cysts are often accompanied by other developmental anomalies of the uropoetic and genital tract. A distinct group is formed by to two syndromes of combined urogenital anomalies: Herlyn-Werner syndrome and Wunderlich syndrome. Seven cases of these syndromes were diagnosed and successfully treated at the Department of Obstetrics and Gynecology in Olomouc.
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In 44 women in the first trimester of pregnancy a single examination of the Ca 125 serum level was made. In 10 women of the control group after mini-interruptions of pregnancy almost in all instances serum concentrations within the normal range were recorded. In 23 women with the diagnosis of spontaneous abortion in the first trimester a mean concentration of 58 U/ml of this protein was found. In a group of 11 women with the diagnosis of imminent abortion with a favourable prognosis, on the other hand, the mean serum concentration was only 42 U/ml, which is close to the mean concentration recorded in the control group of healthy pregnant women (46 U/ml). The difference between the two groups of pathological pregnancies is, however, not statistically significant.
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Beta 2-microglobulin (beta 2-MG) is used as a tumour marker in some malignant diseases. The authors assessed the concentration of beta 2-MG in serum of 30 patients with malignant ovarian tumours and in 29 patients with other benign gynaecological diseases, in particular benign ovarian tumours. Although raised values of beta 2-MG were found in ovarian carcinomas, as compared with the control group of non-malignant gynaecological diseases, a statistically significant increase was recorded only in carcinomas grade III and IV.
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