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Biomedical subjects

M Korobkin

Publications and source records attributed to M Korobkin.

At least 181 records · Page 10Linked to original sources

The portal venous tree simulating dilated biliary ducts on computed tomography of the liver.

Intrahepatic portal veins may be identified on routine computed tomography (CT) of the liver. These venous structures appear as linear and branching, low-density regions in the liver which appear to converge at the porta hepatis. Intrahepatic portal veins may simulate the appearance of dilated intrahepatic bile ducts. Venous structures may be distinguished from dilated bile ducts by their obliteration following intravenous infusion of urographic contrast agents. CT numbers of portal veins tend to be somewhat higher than those of dilated bile ducts, but enough overlap of values exists to make reliance upon these numbers in an individual case suspect.

Bile Ducts, Intrahepatic↗

Renal arteriography in the evaluation of unexplained hypertension in children and adolescents.

Arteriography demonstrated renal artery stenosis in 24% of 101 selected patients whose hypertension was first diagnosed before the age of 20 years. Arteriographic findings were normal in 58%. The prevalence of RAS was greater in the younger than in the older age groups. An abdominal bruit and urographic abnormalities were frequently observed in association with RAS. Adequate follow-up information was available for 16 patients who underwent vascular repair or nephrectomy for RAS. In 14 of the 16, the hypertension was eliminated (81%) or definitely reduced (6%).

Adolescent↗

Segmental renal vein sampling for renin.

Segmental renal vein sampling was performed in 25 hypertensive patients. In those with no arteriographic abnormalities or stenosis of only the main renal artery, renin levels from segmental veins were the same as those from the ipsilateral main renal vein. In patients with an infarction of a renal segment or stenosis of a segmental renal artery, the renin level from the corresponding segmental vein was often much higher than that from the main renal vein. Segmental vein sampling may reveal a significant source of renin production not apparent in samples from the main renal vein.

Catheterization↗

The role of emergency excretory urography in evaluation of blunt, abdominal trauma.

In our hospital, patients seen for blunt, abdominal trauma have an "emergency" urogram. The results of our review of 209 such patients with complete urographic evaluations indicate that (1) the clinical examination, urinalysis, and plain abdominal roentgenogram do not reliably allow one to predict which patients would show urographic abnormalities and (2) the clinical management of these patients is rarely altered by the knowledge of the results of the urogram.

Abdominal Injuries↗

Intrarenal arterial aneurysms.

Intraparenchymal renal aneurysms have been reported with increasing frequency; yet, to our knowledge, this subject has not been reviewed in radiologic literature. The spectrum of such aneurysms includes congenital aneurysms, those secondary to disease usually affecting the main renal arteries, those associated with renal masses, microaneurysms, and false or pseudo aneurysms. Seemingly unrelated conditions, such as atherosclerosis, bacterial endocarditis, and trauma, can all produce similar radiographic appearance of aneurysmal dilatation within the kidney, albeit through differing mechanisms. In addition, there are several etiologies for renal microaneurysms, even though this finding has been considered specific for polyarteritis in the past. Although there were a few guidelines for recognizing certain specific etiologies based solely on the angiographic appearance, it must be appreciated that many of these conditions may be indistinguishable. The possibility of hemorrhage from such intrarenal aneurysms, and the question of whether such lesions are responsible for renovascular hypertension are also discussed.

Adenocarcinoma↗

A simple technique for measuring relative renal blood flow.

To determine whether externally monitored early renal uptake of 131I-hippurate is proportional to renal blood flow, the renal uptake of 131I-hippurate at 1--2 min after injection was compared with the renal accumulation of radioactive carbonized microspheres in dogs. A renal artery catheter equipped with a balloon was used to decrease renal blood flow unilaterally. One minute after the intravenous injection of 100 muCi of 131I-hippurate, about 1 muCi of either 85Sr- or 98Nb-labeled carbon microspheres was injected into the left ventricle. Radioactivity was measured over both kidneys. The total radioactivity within each kidney region of interest was corrected for background and integrated over the 1--2 min after injection. Thirteen measurements of relative renal blood flow were made for seven dogs. The dogs were then killed and both kidneys were excised and counted for the radioactivity of the microspheres. The 1--2-min relative renal uptake of 131I-hippurate correlated well with relative microsphere uptake, suggesting that relative renal blood flow can be simply determined from the external measurement of renal uptake of 131I-hippurate.

Animals↗

Bifurcation of the portal vein appearing as a focal defect on the liver image.

A focal defect was seen on a gamma camera image of the liver in 2 patients, a 52-year-old woman with abdominal pain and a 46-year-old woman with pancytopenia. Liver function was normal, and no tumor stain was seen. Angiography revealed that the "defect" was in reality the bifurcation of the portal vein. These findings re-emphasize the importance of visceral angiography as a complement to radionuclide imaging in the study of liver disease.

Angiography↗

Vesiculographic findings in cysts of the seminal vesicle.

Vasoseminal vesiculography showed medial displacement and stretching of the ampulla of the vas deferens in 3 patients with cysts of the seminal vesicle. In 2 a nonopacified mass separated the ampulla from the ipsilateral seminal vesicle. All 3 patients were managed without surgical intervention. If such a vesiculographic pattern is seen in a patient with a paraprostatic mass, the contents of the mass should be aspirated and contrast material injected to document its cystic nature.

Adult↗

Arteriographic demonstration of collateral arterial supply to the liver after hepatic artery ligation.

Eight patients were studied arteriographically after hepatic artery ligation (done to control bleeding in 6). Sources of arterial flow to the liver after ligation were (a) replaced or accessory hepatic artery; (b) interlobar collaterals in the liver; (c) right inferior phrenic artery; (d) through the gastroduodenal artery from arterial branches in the pancreas, duodenum, and omentum; (e) fine collateral branches of the gastroduodenal artery as they pass into the porta hepatis; and (f) recanalization of the ligated hepatic artery. Collateral vessels, seen as early as four hours after ligation, increase in size and number during the following six months.

Adult↗

Submucosal hemorrhage of the renal collecting system.

Two cases of submucosal hemorrhage in the renal pelvis and ureter are presented. The roentgenographic appearance was identical to that of pyeloureteritis cystica but without evidence of urinary tract infection and, in 1 case, the submucosal impression resolved rapidly. When nodular, submucosal filling defects are demonstrated in the renal collecting system in the clinical setting of anticoagulant therapy or trauma, a diagnosis of submucosal hemorrhage should be considered.

Adult↗