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Biomedical subjects

M Kormano

Publications and source records attributed to M Kormano.

At least 145 records · Page 8Linked to original sources
PubMed1975

Effects of myocardial infarction on adrenergic nerves of the rat heart muscle, a histochemical study.

The anterior branch of the left coronary artery of the rat heart was ligated and the effects of anoxia on adrenergic nerves were studied histochemically using formaldehyde-induced fluorescence for localization of norepinephrine. Greenish catecholamine fluorescence was associated in the normal or infarcted myocardium only with adrenergic nerves. Constant but not prominent changes were seen in adrenergic nerve fibers 2 or 4 h after ligation of the coronary artery; the number of dilicate adrenergic fibers was reduced and some diffusion of the histochemical reaction was seen in small areas of the infarcted myocardium. Strong effects of anoxia were seen 8 h or more after ligation of the coronary artery. These were characterized by a prominent diffusion of the histochemical reaction and gradual disappearance of adrenergic structures in 2 to 4 days of anoxia. During the healing phase the appearance of numerous adrenergic nerve fibers was closely connected with the ingrowth of a new vascular bed into the infarction area. The observations indicate that adrenergic nervous structures of the myocardium resist the effects of anoxia, which may indicate the viability of sympathetic nerves in the infarcted area during long periods of anoxia.

Animals↗
PubMed1975

Psoriatic lesion of the sternal synchondrosis.

Radiography of the synchondrosis between the manubrium and the sternal body was performed in 29 patients with clinically certain psoriatic arthropathy. Tomography proved necessary for a detailed analysis. Erosive inflammatory lesions were detected in 18 cases; in 61 per cent of cases with a history of more than 5 years and in 71 per cent of cases with typical hand and feet arthropathy. It is concluded that the sternum is frequently involved in cases with roentgenologically typical psoriatic arthropathy.

Adult↗
PubMed1975

Effects of 400 R whole-body x-irradiation on 5-hydroxytryptamine content of the rat gastrointestinal tract.

The effects of a single 400 R whole-body dose of X-irradiation on the regional 5HT content of the gastrointestinal (G. I.) tract were studied from four hours to 40 days after irradiation. The total 5HT content of various G.I. tissues was determined and 5HT was also determined per unit of body weight, wet weight of tissue and tissue protein. Irradiation caused an immediate decrease of the amine content of various G.I. regions in adult rats. This was followed by recovery, the degree of which varied in different regions. Some minor morphological changes were seen in enterochromaffin cells one and two days after irradiation but not later. The effects of irradiation on the G.I. tissues were stronger in young rats, in whom no complete recovery of 5HT occurred within 45 days. The present results support the view that irradiation exerts a direct damaging effect on the gastrointestinal 5HT storage, which is associated with liberation of 5HT from amine-containing cells. The duration of the effect varies with age and intestinal segment concerned.

Age Factors↗
PubMed1975

Symphysial changes in rheumatoid arthritis. A microradiographical and histological study.

Autopsied pubic symphyses of 10 male and 10 female non-rheumatoid subjects and of 11 subjects with RA were studied. Osteo-arthritic changes were common in all elderly symphyses. This caused changes in the structure of the end plates and trabeculae. Some non-rheumatoid samples showed changes suggestive of erosion, but no evidence of inflammation. At microradiography the erosions seen in rheumatoid symphyses differed from the controls due to a lack of reactive sclerosis in the surrounding bone, although true inflammation was seen histologically in only two cases.

Adult↗