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Biomedical subjects

M Kon

Publications and source records attributed to M Kon.

At least 91 records · Page 5Linked to original sources

Thigh augmentation.

Based on the experience with calf and buttock augmentation, a new type of implant was designed for thigh augmentation. A case report is presented.

Adult↗

A histological study of cutaneous thermal wounds using a Clostridium perfringens-derived wound healing substance with wound healing stimulation activity.

We studied the effects of a Clostridium perfringens-derived wound-healing substance (WHS) on the healing of thermal burn wounds. Third-degree burn injuries were inflicted on the back skin of rats. We histologically evaluated the effects of WHS ointments and compared them with those of lysozyme chloride ointment. We observed the formation of dermal collagen fibers and the increase of capillaries in the WHS ointment treated groups. From the results of hematoxylin and eosin staining and silver staining, an increase in capillaries was observed one week after the application of WHS ointment. Three weeks after the application, when the epithelization was in the final stage, capillary formation ceased. In the WHS ointment-applied groups, electron microscopic observation showed that new collagen fibers were regularly formed in the dermis. On the other hand, in the lysozyme chloride ointment-applied groups, new collagen fibers were present, but were irregularly formed. The main wound healing stimulative action of the WHS ointment could be due to its acceleration of new capillary formation.

Animals↗

Influence of crystallization on strength and color of castable glass-ceramics containing two crystals.

The mechanical properties, color and transparency of glass-ceramics are highly dependent on the ceramming temperature and/or amount of the crystal phase in the glass matrix. In this study, the influence of crystallization on the strength and color, translucency of castable ceramics containing crystalline apatite and magnesium titanate were measured. It was concluded that magnesium titanate precipitated during ceramming, appeared to be an important factor in decreasing total transmittance and in determination of the color of glass-ceramics.

Apatites↗

Cold (0 degree C) ischaemic tolerance of latissimus dorsi free flaps in rats: a macroscopic and morphological study.

The purpose of this study was to define the cold (0 degree C) ischaemic tolerance (CIT) of the latissimus dorsi free flap in inbred rats. Flaps were isolated, stored at 0 degree C for periods of time ranging from 0 to 120 hr and then revascularised and reperfused for 14 days. Thereafter the CIT was assessed macroscopically, and by light microscopy. Electron microscopy was performed in flaps after 0 and 24 hr of reperfusion following a cold ischaemic interval ranging from 0 to 120 hr. From this preliminary study, it was concluded that the CIT was 48-72 hr.

Animals↗

Shock-absorbing behavior of four processed soft denture liners.

The cushioning effect of soft denture liners was evaluated with the use of a free drop test with an accelerometer. The materials tested included SuperSoft, Kurepeet-Dough, Molteno Soft, and Molloplast-B brands. All materials were found to reduce the impact force when compared with denture base resin. A 2.4 mm layer of soft denture material demonstrated good shock absorption. The Molloplast-B and Molteno Soft materials showed excellent shock absorption. When the soft denture liner was stored in distilled water for 180 days, the damping effect recorded for all materials tested was increased. The aging of all materials also affected the cushioning effect.

Absorption↗

Effect of leucite crystals on the strength of glassy porcelain.

Porcelains with leucite crystals dispersed into various glass matrices were prepared for investigating the effects of the leucite crystals on the mechanical strength of glassy porcelain. The strength of glassy porcelains containing leucite crystals was affected by the differences of thermal expansion coefficients, compositions and deformation temperatures of the glass matrices. In the case of a large mismatch of thermal expansion between the leucite crystals and boro-silicate glass, the strength decreased with increasing amount of leucite. In leucite porcelains using a feldspar glass matrix, there was little or no effect of leucite on the strength. However, the strength of porcelains consisting of leucite crystals and a soda-lime glass matrix was enhanced with increasing leucite content, compared with that of the glassy matrix alone. Such an increase in strength is considered to be because the interface between the glassy matrix and leucite particles occurred in continuous phases, with an effect due to fusion occurring during the transition from leucite particles to the glass phase.

Aluminum Silicates↗

Diffusion of elements in porcelain into titanium oxide.

The diffusion of elements of commercial porcelain for titanium into titanium oxide during heating was investigated. Titanium was deposited on three kinds of disk-shaped porcelains by vacuum-vaporization and the porcelains were then heated. A thin titanium oxide film was formed on the porcelains by the heating. X-ray photoelectron spectroscopy was used to characterize the surfaces of the porcelains with and without titanium oxide. Only sodium, potassium, and barium diffused into titanium oxide during heating, where they formed a complex oxide with titanium. The diffusion of these elements may be involved in the bonding of porcelain to titanium.

Barium↗

Effect of crystallization on fracture strength of castable glass-ceramics containing two crystals.

The relationship between fracture strength and crystallization in castable glass-ceramics was studied using castable glass-ceramics which contained crystalline apatite and magnesium titanate. Bending strength was increased with increases in crystal phases; 90, 124, 122 and 162 MPa were recorded for as-cast specimens and specimens cerammed at temperatures of 905 degrees, 925 degrees and 945 degrees C, respectively. The results of bending tests suggest that the crystallization of magnesium titanate is more effective than that of apatite in increasing the strength of glass-ceramics. Fracture toughness in specimens reheated at 905 degrees C was doubled compared with as-cast specimens. The apatite particles precipitated during ceramming treatment were thought to be an important factor in increasing both the fracture toughness and crack pinning effect.

Apatites↗

Neither desferrioxamine nor lipoic acid enhances the cold ischaemic tolerance of epigastric free flaps in rats.

This study was designed to test the ability of pre- and postischaemic administration of desferrioxamine (DFX), a combination of a preischaemic single passage perfusion with hypertonic citrate solution (HCA) and postischaemic administration of DFX, and pre- and postischaemic administration of lipoic acid (LA) to enhance the cold (0 degree C) ischaemia tolerance in epigastric free flaps in inbred rats. The ischaemic intervals varied between 0 and 120 hr. The area of flap survival 2 weeks after revascularisation as a percentage of original flap size was recorded as an exponent of ischaemic tolerance. None of the treatment regimens was able to increase flap area survival. Histologically, there were no major differences between the different treatment regimens.

Adipose Tissue↗

Non-revascularized epigastric free flap: no all-or-none survival pattern.

We have previously shown that the epigastric flap in Dark Agouty rats, measuring approximately 6 x 4 cm with borders related to well-defined anatomical structures, does not exhibit an all-or-none survival pattern. This study was designed to investigate the survival pattern of non-revascularized epigastric flaps in three other rat strains (Sprague-Dawley, Brown-Norway, and Lewis). In concordance with our earlier observations, but in contrast to reports by many other groups, in none of the used strains was an all-or-none survival pattern observed. Survival varying from 2 to 30% (mean, 12%) of the original flap, without significant differences between the strains, was found. The locations of survival exhibited a clear pattern, probably owing to the fat pad in the subcutis and revascularisation from the recipient wound edges.

Adipose Tissue↗

The benefit of a single-passage perfusion with a hypertonic citrate solution on the cold ischemia tolerance of epigastric free flaps in Dark-Agouty rats.

In this study the effectiveness of a single-passage perfusion with hypertonic citrate solution on the cold ischemia tolerance in epigastric free flaps in Dark-Agouty rats was investigated. In the control group a significant decline in survival percentage was observed when the storage time was extended from 72 hours to 96 hours. A single (pressure controlled) passage perfusion with hypertonic citrate solution was able to prevent this decline.

Animals↗

Effect of adding diamond particles on the fracture toughness of apatite ceramics.

Composite ceramics dispersed through diamond particles with hydroxyapatite as a matrix were prepared by firing at 1250 degrees C under reduced pressure or normal atmosphere. The fracture toughness and physical properties of sintered composite ceramics were examined to determine methods of strengthening hydroxyapatite ceramics. The diamond crystal in composite ceramics was transformed to graphite by firing and the fracture toughness of hydroxyapatite ceramics increased with diamond addition. At 10 wt% diamond, the maximum value for fracture toughness was obtained, and the further addition of diamond particles over 10 wt% caused fracture toughness to decrease. Such increases in fracture toughness were considered the result of microcracking which occurred during the transformation from diamond to graphite.

Dental Porcelain↗

Survival characteristics of the epigastric free flap in DA-rats.

Epigastic flaps measuring approximately 6 x 4 cm with borders related to well-defined anatomical structures were isografted (Dark Agouty to Dark Agouty inbred rats) with or without anastomosing their epigastric pedicle, after various periods of ischaemia, ranging from 0 to 120 h. During the ischaemic insult the flaps were stored at 0 degrees C in a hypertonic citrate solution. The non-revascularized flaps exhibited survival percentages varying from 2 to 34% (mean, 16%) of the original flap,. independent of the storage interval. The flaps that were revascularized after ischaemia had a 100% survival when transplanted immediately after isolation and following 48 h of cold storage. Mean survival percentages of 78% after 72 h of ischaemia, 32% after 96 h, and 4% after 120 h of ischaemia were found. It is concluded that the model described in this study is suitable for free flap research, because of its delineated borders. However, when the area of flap survival is lower than 30% in revascularized flaps there is a distinct likelihood that the flaps have survived regardless of the pedicle as simple Wolfe or composite grafts. Results must therefore be interpreted with great care.

Animals↗

Cutaneous trunci myocutaneous flap: a new and reliable model for muscle free flap research in the rat.

This paper deals with the first myocutaneous flap in the rat. It is located just caudal to the axilla and consists of the insertion of the cutaneous trunci muscle with overlying subcuticular fat and skin and is supplied by the lateral thoracic vessels. It exhibits an all-or-none survival pattern. Because the skin can serve as a marker for muscle viability, we believe that this flap has great potential in future free muscle research.

Adipose Tissue↗

Geometrical approach to the end-to-side anastomosis.

We analyzed the procedure of performing an arterio- or venotomy in rats and changed it from parallel to the long axis to perpendicular to the long axis. Simultaneously, geometrical analysis of the shape of an arterio- or venotomy led to a new approach for the end-to-side anastomosis in experimental free flap transplantation. This new method was applied in 268 anastomoses. It necessitated only six sutures and resulted in 100% arterial early and late patency and in 99% venous early and late patency.

Anastomosis, Surgical↗

Firework injuries to the hand.

Hand injuries by fireworks occur every year especially around New Year's Eve. These complex injuries show a combination of avulsion, laceration, blast, crush and burns. Three typical cases are presented and their treatment is outlined.

Adolescent↗