[Infections due to Yersinia enterocolitica].
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Adolescent↗
Biomedical subjects
M Kist
Publications and source records attributed to M Kist.
[Salmonella freiburg: a new salmonella-serotype (3,10:1,Z13:1,2) (author's transl)].
A new Salmonella serotype (S. 3,10:1,Z13:1,2) was isolated from a stool specimen of a 13 year old immigrant from Narpan, USSR. The strain was finally identified as a new Salmonella, Subgenus I, on August 10, 1975 by Prof. Le Minor, International Salmonella Centre, Paris. The organism was introduced into the Kauffmann-White-Scheme, Supplement XX, as S. freiburg.
Adolescent↗
Differences in the isoelectric focussing pattern of antibodies to human serum albumin eluted from an immunoadsorbent (HSA-sepharose) with thiocyanate ions.
Anti HSA-antibodies were isolated from HSA-sepharose by direct and stepwise elution with 0.5 M, 2.0 and 3.0 M KSCN at different pH values. The antibody fractions, especially those eluted stepwise, varied in their isoelectrofocussing pattern. Nearly all antibody molecules with an isoelectric point (PI) lower than 6.5 were eluted with 0.5 M KSCN. Application of increasing KSCN concentrations led to the recovery of antibody fractions showing a parallel shift in the PI to the region higher than 7.5. These differences were not correlated with differences in antibody avidity. The effect of KSCN does not seem to be restricted to the combining sites of the antibody. The dissociation of the antibody from the antigen is apparently facilitated by an interaction of KSCN with the remainder of the antibody molecule thereby influencing the overall net charge.
Animals↗
Asymmetric synthesis and structure-activity relationship of the four stereoisomers of the antibiotic amidinomycin. Part 2: Microbiological testing.
The stereoisomers of amidinomycin 7 and their intermediates 1-6, which are produced from homochiral 3-oxocyclopentanecarboxylic acids by asymmetric synthesis, are tested for their antimicrobial effects by agar diffusion test and by Bouillon serial dilution assay. Their antibiotic activities against Bacillus subtilis, Staphylococcus aureus, and Micrococcus Iuteus, respectively, are reported. Structure-activity relationships depend on the type and combination of functional groups, on only the relative stereochemistry as well as on the grade of lipophilia of the tested compounds.
Anti-Bacterial Agents↗
Campylobacter coli septicaemia associated with septic abortion.
A 19-year-old patient was 27 weeks pregnant when admitted to hospital with fever, chills and premature labours. The following day she aborted. Campylobacter coli was isolated from blood cultures, maternal placenta and amniotic fluid and from the ear, nose and pharynx of the stillbirth. Campylobacter could not be isolated from stool specimens after antimicrobial treatment had been started.
Abortion, Septic↗
Helicobacter pylori infection does not correlate with plasma ammonia concentration and hepatic encephalopathy in patients with cirrhosis.
BACKGROUND/AIMS: In patients with cirrhosis, infection of the stomach with Helicobacter pylori may increase ammonia production and, consequently, the incidence of hepatic encephalopathy. To test this hypothesis a retrospective analysis was performed in patients with a transjugular intrahepatic portosystemic shunt. These patients are regarded to be ideal candidates for such a study since they have a high bioavailability of gut-derived ammonia and many of them develop spontaneous hepatic encephalopathy. METHODOLOGY: In 132 patients (Child-Pugh class A: 24%, B: 49%, C: 27%) with stable transjugular intrahepatic portosystemic shunt function for more than 3 months (mean follow-up: 15.5 +/- 10.8 months) the diagnosis of H. pylori infection was established by a specific and sensitive immunoblot assay for IgG- and IgA-antibodies. During follow-up, hepatic encephalopathy was assessed by clinical examination and a structured questionnaire. Venous plasma ammonia concentration was measured at the time of antibody determination (end of study period). RESULTS: Eighty-four patients (64%) had negative and 48 patients (36%) had positive immunoblots for H. pylori. The groups were comparable with respect to age, gender, etiology of cirrhosis, Child-Pugh class, follow-up after transjugular intrahepatic portosystemic shunt, and shunt function. The ammonia concentrations of the patients without (group 1) and with antibodies against H. pylori (group 2) were 73 +/- 27 and 69 +/- 28 mumol/L (mean +/- SD), respectively. Hepatic encephalopathy occurred in 23 of 84 patients (27%) of group 1 and in 11 of 48 patients (23%) of group 2. CONCLUSIONS: A positive immunoblot for H. pylori antibodies neither correlates with plasma ammonia concentration nor with the incidence of hepatic encephalopathy in patients with cirrhosis of the liver and portosystemic shunt.
Adult↗