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Biomedical subjects

M Janssens

Publications and source records attributed to M Janssens.

66 records · Page 4Linked to original sources
PubMed1984

Semisolid selective-motility enrichment medium for isolation of salmonellae from fecal specimens.

A semisolid selective-motility enrichment medium for the isolation of salmonellae from fecal specimens was developed which was based on Rappaport enrichment broth. During a 7-year period more than 30,000 stool samples were tested. The medium showed a high specificity (95.1%) and sensitivity (80.3%) when compared with MacConkey agar, SS agar, and brilliant green agar (after Selenite-F Enrichment [BBL Microbiology Systems]). Furthermore, our isolation rate of Salmonella species from fecal samples showed an increase of 22.3% when this semisolid medium was added to the routine culture media. Growth could easily be interpreted. The medium has a bias toward the isolation of Salmonella paratyphi B, but it is unsatisfactory for detecting the nonmotile strains Salmonella typhi and S. paratyphi A.

Culture Media↗
PubMed1982

[Pathogenesis of post-irradiation infection. 2. Role of polynucleated neutrophils in the defense of irradiated rats against Yersinia enterocolitica].

Wistar R inbred rats showed a substantial mortality when they were given Yersinia enterocolitica eight days after a 6.5 Gy total body irradiation. The possibility to abolish the high susceptibility of these irradiated rats to Yersinia enterocolitica by intravenous injections of isogenic neutrophils is presented: irradiated rats injected with 7 to 10.10(7) isogenic neutrophils, by the intravenous route, just before or after the administration of Yersinia enterocolitica, were not susceptible. On the contrary, control irradiated rats, not transfused, were killed by the same bacterial challenge.

Animals↗
PubMed1981

Pathogenesis of post-irradiation infections. I. Yersinia enterocolitica administered to normal and irradiated rats.

Infections after irradiation can be due to a great variety of microorganisms many of which are normally non-pathogenic or conditionally pathogenic for the host. The strain of Y. enterocolitica used was not pathogenic to a variety of unirradiated rats nor to athymic or B lymphocyte deprived, macrophage depleted rats, nor to normal rats irradiated by 5.7 Gy 24 hours before. However similarly irradiated rats receiving Y. enterocolitica 5 to 10 days later showed a substantial mortality. It is concluded that the radiosensitive mechanism for protection against Y. enterocolitica is not humoral nor cellular immunity as mediated by T and B lymphocytes or macrophages.

Animals↗
PubMed1979

The superior oblique: a challenging extraocular muscle.

Isolated paralysis of one or both superior oblique muscles in a consecutive series of 43 patients was found to occur most often by indirect injury to the skull. The etiology in the group of spontaneous cases was mostly vascular. With rare exceptions the latter recovered spontaneously. Those with traumatic palsy may be due to "contrecoup" trauma at the decussation of the nerves or by decompensation of the cerebral fusional mechanism, with dissociation of the images of the two eyes and subsequent vertical deviation. The traumatic cases never recover spontaneously and recession or myectomy of the ipsilateral inferior oblique with or without recession of the contralateral inferior rectus is recommended but only in cases of more than 8 diopters squint, and in cases which do not adapt themselves by minor head-tilting.

Adult↗
PubMedDate not supplied

Pasteurella multocida in peritoneal dialysis: a rare cause of peritonitis associated with exposure to domestic cats.

Pasteurella multocida is a rare cause of peritonitis in peritoneal dialysis patients with only 10 cases reported in the literature so far. All cases were observed in patients with close contact with cats, usually with a direct puncture of the dialysis tubing. We report a case of Pasteurella multocida peritonitis in a patient maintained under continuous cycling peritoneal dialysis (CCPD), who had frequent and close contact with cats. Patients should be made aware of this potential complication and advised to keep domestic animals away from the location of their peritoneal exchanges.

Adult↗
PubMedDate not supplied

[Heparin-associated thrombocytopenia].

Thrombocytopenia and heparin. Heparin associated thrombocytopenia (HAT), more specially type 2, is an important complication of anticoagulant treatment in clinical practice. Diagnosis may be difficult and requires special laboratory techniques. Platelet count should be performed every two days. Severe complications may occur in 23% of type 2 HAT patients and is associated with a high mortality. Until now there are no prophylactic measurements for high risk patients.

Female↗