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Biomedical subjects

M Janota

Publications and source records attributed to M Janota.

At least 55 records · Page 3Linked to original sources

Antiarrhythmic effect of Mercurascan in patients after surgical treatment of ischaemic heart disease.

Premature ventricular contractions are relatively often encountered in patients after surgical treatment of ischaemic heart disease. Mercurascan (MSC), given at 0.05 mg/kg of body weight, favourably affected both the incidence and duration of arrhythmia. Unlike other antiarrhythmics, MSC did not affect the heart rate nor blood pressure. Postoperative treatment of ventricular arrhythmia with MSC is a promising procedure and merits further clinical and experimental investigation.

Anti-Arrhythmia Agents↗

[Tonus of respiratory muscles in acetycholine hypotonia (author's transl)].

The importance of respiratory muscles in relation to circulation and ventilation was investigated in acute hypotonia after acetylcholin injection. The tonus of respiratory muscles was assessed by measuring the circumference of chest and abdomen. Changes of volume of the body cavities were examined by body plethysmography. A significant relation between the increase of circumferences of the chest and abdomen and increase of lung volume was registered. The authors conclude, that the tonus of the respiratory muscles determines the volume of chest and abdomen and influences the distribution of blood.

Acetylcholine↗

Reproducibility of exercise tests in patients with symptomatic ischaemic heart disease.

In 50 patients with ischaemic heart disease prospective analyses of the reproducibility of exercise tests at 3-month intervals were performed. The same method of testing was used repeatedly in a smaller group of patients 3 or more times at 6- to 8-week intervals. No significant differences were found in maximal heart rate, maximal systolic blood pressure, rate-pressure product, and total work. Symptoms resulting in the discontinuation of exercise were unchanged in 94 per cent of patients. The evaluation of the electrocardiographic recordings revealed good agreement in 94 per cent of patients. The evaluation of the electrocardiographic recordings revealed good agreement in ST segment depression and ST segment elevation. The reproducibility of arrhythmic events was very poor. The standardized electrocardiographic exercise test is, therefore, recommended for objective evaluation of various interventions in patients with manifest ischaemic heart disease, both in short-term and long-term follow-up studies.

Angina Pectoris↗