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Biomedical subjects

M Janota

Publications and source records attributed to M Janota.

At least 37 records · Page 2Linked to original sources

The diagnostic value of R-wave amplitude changes during exercise testing.

Exercise ECG, coronary arteriography and left ventriculography were performed in 200 patients with suspected or confirmed coronary artery disease (CAD). The authors compared the diagnostic value of R wave amplitude changes and ST segment depressions in V5. Evaluation of the results showed a near uniform sensitivity of the two methods. R wave amplitude changes in V5 did not correlate with the presence and degree of CAD nor with the number of affected coronary arteries. In contrast to the absence of a definite correlation with topical left ventricular dysfunction there was a correlation with the ejection fraction. The study showed that in some instances R wave amplitude changes may complement the evaluation of exercise testing based on ST segment depressions. Yet, R wave amplitude changes alone during exercise testing lack a sufficient predictive accuracy for being adopted as a routine criterion of coronary insufficiency.

Adult↗

The prognosis of ischaemic heart disease. Significance of the sub-maximum ECG exercise test and coronary angiography.

The authors evaluate the long-term fate of 1,254 conservatively treated patients suffering from ischaemic heart disease (IHD), in dependence on the results of submaximal ECG exercise test and coronary angiography. Survival rate was closely related to the heart rate achieved during exercise, the duration of exercise, presence or absence of subjective or ECG signs of coronary insufficiency during exercise, and on the degree of impairment of coronary circulation. Comparison of invasively and non-invasively obtained data confirms that submaximal ECG exercise test can contribute to a more accurate assessment of prognosis in patients with double- or triple-vessel coronary heart disease.

Angiography↗

Fate of patients 1--6 years after operation on account of coronary artery disease.

The authors analyzed the fate of 234 patients 1--6 years after operation of the coronary arteries. In the majority of patients they recorded alleviation of complaints and improved physical performance. Part of the patients resumed employment. Successful revascularization of the heart muscle improved the mechanical function of the left ventricle. Indirect comparisons suggest that the number of patients who survived late myocardial infarction and late mortality are lower in operated patients than in similar patients treated only conservatively. Final evaluation of all possible methods of surgical treatment of the coronary arteries will call for further work. The experience as regards indications, surgical tactics and techniques in postoperative care assembled during the past period improve fundamentally the immediate results of surgical treatment of coronary artery disease and this must be manifested also in the subsequent fate of these patients.

Coronary Disease↗