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Biomedical subjects

M J Moore

Publications and source records attributed to M J Moore.

193 records · Page 11Linked to original sources
PubMedDate not supplied

The dual connective tissue system of rat soleus muscle.

Rat soleus muscle has two types of connective tissue associated with it which do not overlap except at the myotendinous junction. One, an areolar type, is restricted mainly to the spaces between muscle fibers and the other, a regular dense type, is located only beyond the ends of muscle fibers in structures called microtendons. The definitive tendon of a muscle thus represents the accumulation of all the microtendons, one of which is contributed by each muscle fiber. The diameter distributions were the same for collagen fibrils from areolar tissue and microtendons but different from tendon collagen. Marked changes occur in the diameter distribution of the microtendon collagen as it passes into and blends with that of the tendon.

Animals↗
PubMedDate not supplied

The DNA sequence and comparative analysis of human chromosome 20.

The finished sequence of human chromosome 20 comprises 59,187,298 base pairs (bp) and represents 99.4% of the euchromatic DNA. A single contig of 26 megabases (Mb) spans the entire short arm, and five contigs separated by gaps totalling 320 kb span the long arm of this metacentric chromosome. An additional 234,339 bp of sequence has been determined within the pericentromeric region of the long arm. We annotated 727 genes and 168 pseudogenes in the sequence. About 64% of these genes have a 5' and a 3' untranslated region and a complete open reading frame. Comparative analysis of the sequence of chromosome 20 to whole-genome shotgun-sequence data of two other vertebrates, the mouse Mus musculus and the puffer fish Tetraodon nigroviridis, provides an independent measure of the efficiency of gene annotation, and indicates that this analysis may account for more than 95% of all coding exons and almost all genes.

Animals↗
PubMedDate not supplied

Relaxation training as a nursing intervention versus pro re nata medication.

To determine the effect of relaxation training on the frequency of intake of pro re nata medication for relief of tension and to compare the difference between live and taped instructions of this training 60 patients on PRN minor tranquilizers and sedatives in one nursing unit were studied. Subjects were randomly assigned to three groups: group A, control; group B, live instruction; group C, taped instruction. Dependent variables monitored were: 1) frequency of intake of PRN medication; 2) pre- and postinstruction change in blood pressure, pulse, and respiration; 3) change in the Taylor Manifest Anxiety Scale; and 4) change on the Minnesota Multiphasic Personality Inventory score. Although no significant difference was found between method of relaxation training, there was evidence that group B surpassed group C in terms of benefit of the treatment. Physiologic variables as well as MMPI scales K, I, and VII yielded better results for group B. Not all variables demonstrated significant differences. Groups B and C were more similar at the conclusion of the study than had been anticipated-perhaps because subjects responded favorably to inclusion in the study regardless of method of training.

Analysis of Variance↗