Search PubMed⌕ Search

Biomedical subjects

M J Dodd

Publications and source records attributed to M J Dodd.

At least 55 records · Page 3Linked to original sources

The development and testing of a nursing model of morbidity in patients with cancer.

Although oncology nurses are concerned about patient morbidity associated with cancer and its treatment, a comprehensive morbidity model from the perspective of nursing has yet to be developed. The purpose of this study was to begin to develop a morbidity model relevant to patients with cancer receiving treatment in the ambulatory care setting. The model was empirically tested with a sample of 100 patients with cancer beginning chemotherapy. Three domains emerged from the model: physiologic/pathophysiologic, functional, and psychological. Indices of morbidity within each domain were tested to establish beginning reliability and validity of the model. The results that were obtained indicate significant correlations among many of the indices within each domain (e.g., performance status, mood disturbance, patients' ratings of their current health); other indices did not contribute significantly to the model (e.g., type of cancer, history of recurrent disease, and patients' assessments of their health prior to developing cancer). Although further testing and refinement of the model is indicated, these preliminary findings reflect the model's potential for significant clinical relevance. By using this model, nurses could more readily profile patients at risk for increased morbidity and target their interventions accordingly.

Activities of Daily Living↗

Efficacy of proactive information on self-care in chemotherapy patients.

The purpose of this longitudinal experimental study was to test the efficacy of providing side effect management (SEM) information proactively for chemotherapy patients. The proactively experimental intervention consisted of presenting SEM information on all side effects the patient was susceptible to develop, prior to the development of any side effects. A control of like patients received the standard information provided in the setting. Sixty patients initiating chemotherapy (CT) were randomized into either the experimental or the control group. They recorded their experienced side effects of CT in their self-care behavior (SCB) logs. Measurements of state-trait anxiety (STAI) and locus of control occurred at the beginning and 6 weeks later. Patients receiving SEM proactively performed significantly higher scores on all of the SCB ratios and preventive activities. These patients did not initiate self-care with less delay or before the side effects became more severe than the control group patients. Performance status increased significantly for the experimental group patients between interviews (initial and 6 weeks). The findings are in contrast to a parallel study with radiation therapy patients and extend and enhance understanding of self-care practice.

Drug-Related Side Effects and Adverse Reactions↗

Measuring informational intervention for chemotherapy knowledge and self-care behavior.

Little is known about how cancer patients manage the side effects of chemotherapy, so 48 cancer patients in chemotherapy were randomized into four groups to determine their self-care behaviors. The first group received drug information only; the second group received information on side-effect management techniques (SEMT); the third group received combined drug and SEMT information; the fourth group were controls. Pre- and postintervention scores on chemotherapy knowledge, self-care behavior, and general affective state were evaluated by analysis of covariance. Patients who received drug information alone or in combination with other information had higher chemotherapy knowledge scores. Patients who received SEMT information alone or in combination with other information performed more self-care behaviors. Although an additive effect of combined information was noted, i.e., patients who received both types of information showed improved chemotherapy knowledge and self-care behaviors, the combined information did not produce a significantly improved affective state.

Affect↗

Histocompatibility antigens and rheumatic diseases.

Great advances have been made during the last 10 years in the field of immunogenetics as applied to the rheumatic diseases. The association of particular rheumatic diseases with the gene products of the major histocompatibility system provides convincing evidence of a genetic basis for disease susceptibility and has enabled identification of genetic heterogeneity within disease groups. This review briefly discusses the biology of HLA system and its relevance for rheumatology today.

Animals↗

Pyogenic arthritis due to bacteroides complicating rheumatoid arthritis.

Two cases of anaerobic, pyogenic arthritis complicating rheumatoid disease due to bacteroides are described. The relative well-being of the patients and indolence of the affected joints are emphasised, and the effective role of metronidazole in the treatment of septic arthritis due to bacteroides is discussed.

Aged↗