Search PubMed⌕ Search

Biomedical subjects

M Iio

Publications and source records attributed to M Iio.

At least 145 records · Page 8Linked to original sources
PubMed1986

Magnetic resonance imaging of clival chordomas.

Chordoma of the clivus is one of the skull base tumors which originate from the remains of the notochord. The magnetic resonance findings in six patients are reported. The tumors showed slightly low intensity on T1 weighted images, but high intensity on T2 weighted images. The localization of the tumor was easily recognized by the disappearance of the normal signal in the clivus. Compression of the pons and medulla oblongata was readily diagnosed on sagittal images. A normal pituitary gland was demonstrated in all cases. Magnetic resonance imaging was useful for the diagnosis and for the surgical treatment of these chordomas.

Adolescent↗
PubMed1985

Synthesis of pyruvate-1-11C as a radiopharmaceutical for tumor imaging.

Pyruvate-1-11C was prepared enzymatically by the exchange reaction of 11CO2 with the carboxyl group of pyruvic acid using pyruvate-ferredoxin oxidoreductase from Clostridium butyricum. 11C-Labeled pyruvate was purified by sublimation in specially made glassware. The radiochemical yield of pure pyruvate-1-11C was 80% 35 min after the end of bombardment. The distribution of 11C in tumor-bearing rabbits after an i.v. injection of pyruvate-1-11C was observed using a gamma camera. In contrast to normal organs, the tumor was positively visualized. We also conducted a number of successful clinical studies. A case of brain tumor which exhibited a positive image on positron-emission tomography (PET) using pyruvate-1-11C is presented.

Animals↗
PubMed1985

Benefit of transcatheter arterial embolization for ruptured hepatocellular carcinoma complicating liver cirrhosis.

In 6 patients with spontaneous rupture of hepatocellular carcinoma complicating liver cirrhosis, but with no occlusion of the main portal trunk, transcatheter arterial embolization was performed within 7 days of the rupture. All 6 patients were thought to be inoperable because of shock state or severe hepatic dysfunction. In all 6 patients, the progressive decrease in the hematocrit ceased soon after the embolization. Five patients survived for 31-168 days after the embolization; 1 patient who developed septicemia died 10 days later. We conclude that transcatheter arterial embolization is beneficial as a procedure of first choice for ruptured hepatocellular carcinoma when the portal blood flow is maintained.

Adult↗
PubMed1985

Hepatic tumors: differentiation by transverse relaxation time (T2) of magnetic resonance imaging.

Fifty-three patients who had hepatic tumors (24 hepatomas, ten metastases, and 19 cavernous hemangiomas) underwent MR imaging using a 0.35-T superconducting imager. The transverse relaxation time (T2) was calculated from a pair of spin echo images (repetition time [TR] of 1600 msec) with echo delay times (TE) of 35 and 70 msec. The computed T2 value was obtained in a fashion similar to that used to obtain CT numbers with region-of-interest cursors. The mean T2 was 59 +/- 9 msec in hepatomas, 64 +/- 15 msec in metastases, and 100 +/- 30 msec in hemangiomas. The difference between the T2 of hemangioma and that of liver malignancies was statistically significant (P less than .001); however, differentiation between hepatoma and metastases was not possible. The T2 was shorter than 80 msec in all 24 hepatomas and in nine of ten metastases, and was longer than 80 msec in 16 of 19 hemangiomas. Forty-nine of 53 cases (92%) were correctly classified when the borderline of T2 between hemangioma and hepatic malignancies was set at 80 msec. MR with T2 calculation was valuable in differentiating between hemangioma and hepatic malignancies.

Carcinoma, Hepatocellular↗
PubMed1985

Embolism detection and prevention using scintigraphy during therapeutic arterial blockade.

We describe an application of simple scintigraphic localization of therapeutic gelatin emboli during and after transcatheter arterial embolization using gelatin particles labeled with technetium 99m. This scintigraphy required an additional 15-30 minutes and can be useful for prevention of serious complications and for early detection of adverse embolisms.

Arteries↗