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Biomedical subjects

M Iio

Publications and source records attributed to M Iio.

At least 235 records · Page 13Linked to original sources
PubMed1981

A comparison between the computed tomogram and the neuropathological findings in cerebrovascular disease.

The findings on computed tomography (CT) and neuropathological examinations were correlated in 87 autopsied cases of cerebrovascular disease with regard to the seize and location of lesions, experience of reviewers, and improvement in CT quality. Small infarctions less than 5 mm were very difficult to detect accurately on CT. This was largely because of the limitations in the efficiency of the CT scanner. Accurate diagnosis of medium sized infarctions was also often difficult. This was mainly due to the anatomical location of lesions, the confluence of deep and widened sulci, periventricular white matter, and structures in the posterior fossa. Large infections could be visualized easily on CT, except in their early periods or in cases with hemorrhagic infarctions. The improved accuracy of CT diagnosis for small and medium sized infarctions could not be attained by the experience of reviewers, but was only possible by instrumental improvement of CT quality.

Cerebral Hemorrhage↗
PubMed1981

Advanced technologies of cardiovascular nuclear medicine and their evaluation in clinical practice.

Currently available advanced methods of cardiovascular nuclear medicine for the diagnosis of ischemic heart disease were studied. The methods included the multigate method by a large capacity gamma camera-computer (128 KW memory with multilayer disc) system which made it possible to acquire the data of either the first pass study or the equilibrium study in "imaging mode". Analyzed data were displayed on a color CRT using our moving image system (MIS) and dynamic image thus obtained serve to help for the high sensitive observation of the regional wall motion as well as the global function of the ventricles. Myocardial tomography by a 7 pinhole collimator designed by us was also reported. The myocardial tomogram obtained was proved to show more sensitivity than two dimensional myocardial scan by the conventional collimator to detect smaller lesion and the lesions at the inferior or posterior wall of the left ventricle. The cardiovascular nuclear medicine with recent advanced technologies was thought to be sensitive and useful method for the diagnosis of the ventricular performance and the myocardial ischemia.

Aged↗
PubMed1981

[Studies of interventricular septal motion after heart valve replacement by two-dimensional echocardiography and thallium 201 scintigraphy (author's transl)].

Etiology of abnormal interventricular septal motion detected by M-mode echocardiography after heart valve replacement was studied by two-dimensional echocardiography and thallium 201 scintigraphy in three patients with valvular heart disease (two with mitral regurgitation, and one with aortic regurgitation). M-mode and two-dimensional echocardiograms were recorded before and after heart valve replacement, using Aloka SSD-800. After intravenous injection of 2.0 mCi of ionic thallium 201, myocardial images were recorded with a scintillation camera (Searle PHO Gamma V) with converging collimator. Abnormal interventricular septal motion (systolic anterior motion) was observed echocardiographically in all of three patients after mitral or aortic valve replacement. Two-dimensional echocardiogram showed systolic anterior motion of the whole heart towards the anterior chest wall, though the left ventricle itself contracted normally. Thallium 201 scintigram showed no significant perfusion defects of the left ventricular wall including ventricular septum. No findings showing conduction disturbance, right ventricular volume overload or pericardial effusion were observed after heart valve replacement.

Adult↗
PubMed1981

[Analysis of RIA standard curve by log-logistic and cubic log-logit models (author's transl)].

In order to improve goodness-of-fit in RIA standard analysis, programs for computing log-logistic and cubic log-logit were written in BASIC using personal computer P-6060 (Olivetti). Iterative least square method of Taylor series was applied for non-linear estimation of logistic and log-logistic. Here "log-logistic" represents Y = (a--d)/(1+log(X)/c)b)+d As weights either 1, 1/var(Y) or 1/sigma 2 were used in logistic or log-logistic and either Y2(1--Y)2, Y2(1-Y)2/var(Y), or Y2(1--Y)2/sigma 2 were used in logistic or log-logistic and either Y2(1--Y)2, Y2(1--Y)2/var(Y), or Y2(1--Y)2/sigma 2 were used in quadratic or cubic log-logit. The term var(Y) represents squares of pure error and sigma 2 represents estimated variance calculated using a following equation log(sigma 2 + 1) = log(A)+J log(y). As indicators for goodness-of-fit, MSL/Se2, CMD% and WRV (see text) were used. Better regression was obtained in case of alpha-fetoprotein by log-logistic than by logistic. Cortisol standard curve was much better fitted with cubic log-logit than quadratic log-logit. Predicted precision of AFP standard curve was below 5% in log-logistic instead of 8% in logistic analysis. Predicted precision obtained using cubic log-logit was about five times lower than that with quadratic log-logit. Importance of selecting good models in RIA data processing was stressed in conjunction with intrinsic precision of radioimmunoassay system indicated by predicted precision.

Computers↗
PubMed1980

The diagnosis of the gastric cancer by radionuclides and their labels, using catheter-type semiconductor radiation detector (CASRAD).

New method of differential diagnosis of gastric cancer was reported. After intravenous 32P administration, lesion was counted by small catheter-type readiation detector system under gastrofiberscopic direct vision control. Optimum counting time was examined in man and it was found to be between 20 to 50 hours after intravenous administration of 32P. Under the currently available technology of miniature detector, still beta-emitting carcinopohilic agent was found to be the agent of choice to this end, since gamma-emitting carcinophilic agents can not provide data originated only from the gastric mucosa in question.

Catheterization↗