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Biomedical subjects

M Iida

Publications and source records attributed to M Iida.

At least 631 records · Page 35Linked to original sources
PubMed1979

Turcot's syndrome and its mode of inheritance.

Two sisters with Turcot's syndrome, in which malignant cerebral neoplasms are associated with colonic polyposis, are presented. Cases reported in the literature, including some familial cases, have also been analysed. In familial cases, sex was unrelated to the occurrence of this disease and it was found only among siblings of the same parents and not in other members of the family. There was consanguinity in the parents of the patients in two out of three families. We therefore concluded that the mode of inheritance in this condition is autosomal recessive and that it is genetically distinct from the ordinary form of familial polyposis coli. Support is lent to the absence of an association between the two disorders by a difference in the number, size, and distribution of the colonic polyps found in Turcot's syndrome as compared with familial polyposis coli.

Adenoma↗
PubMed1979

[Multiple osteosarcoma in spontaneously hypertensive rats (author's transl)].

For period from 1971 to 1975, 18 cases of osteosarcoma were experienced among 9132 spontaneously hypertensive rats. The onset was at 72 to 145 days of age and death occurred before 423 days of age. The tumors were multiple being distributed in the skull (11 of 14 cases), caudal vertebrae (8 of 14 cases), and fore- and hind-limb. All the tumors were mainly composed of sarcomatous tissue with some osteoid and cartilage. Metastasis was never observed. Serum A1-P levels of tumor bearing animals were 2 times higher than those without tumor. Bronchiectasis and abscess formation of submaxillary lymph nodes were noted in most affected animals.

Alkaline Phosphatase↗
PubMed1978

Juvenile type of distal and segmental muscular atrophy of upper extremities.

Seventy-one cases of distal and segmental muscular atrophy of the upper extremities with juvenile onset were studied. The clinical features consisted of: juvenile onset, male preponderance, unique distribution of the muscular atrophy in the hand and forearm, tendon reflexes hypoactive in most cases but hyperactive in some, no definite sensory disturbances, no involvement of the cranial nerves, and autonomic nerve disorders in the affected region. There was rapid progression during the 2 to 3 years after onset with a slowly progressive course thereafter. There were no abnormal laboratory findings except for electrophysiological and morphological findings of the affected muscles. The site of lesion was surmised to be from the C5 to T1 spinal segments with intramedullary involvement. The cause is unknown.

Adolescent↗
PubMed1978

[Two years feeding toxicity study of tamarind seed polysaccharide in rats (author's transl)].

Tamarind seed polysaccharide (Glyloid) was incorporated at the level of 4, 8, 12% in a standard commercial diet and fed ad lib. to male and female rats for 2 years. No significant changes were noted in the behavior, mortality, body weight, food intake, biochemical analysis of urine and blood, hematological test, organ weight and histopathological findings of rats receiving Glyloid. In all groups containing control group, spontaneous diseases with aging, such as myocardial change, nephropathy, mammary tumor (in female), pituitary tumor etc., were seen. These diseases played important role as the cause of death of the dead rats.

Animals↗
PubMed1977

Renal secondary hyperparathyroidism in aged Sprague-Dawley rats.

Fourteen aged Sprague-Dawley rats had typical renal secondary hyperparathyroidism. The renal disease was severe glomerulosclerosis with tubular dilation. The parathyroid glands were enlarged and had hyperplasia of chief cells. Bone lesions were generalized osteodystrophia fibrosa and osteosclerosis. All rats had osteodystrophia fibrosa and it was severe in 10 rats. Only four rats had osteosclerosis and it was moderate. Metastatic calcification was seen in various soft tissues in 13 rats.

Age Factors↗