Stop IPPB therapy!
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Biomedical subjects
Publications and source records attributed to M I Gold.
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The IBC in-vivo oxygen electrode may be used during anesthesia. The possibility that three common inhalation anesthetics--halothane, enflurane, and methoxyflurane--might be reduced at the electrode, thereby changing the PO2 value, was tested. Enflurane and methoxyflurane do not affect the current produced at the electrode; halothane significantly increases PO2 readings at oxygen tensions below 105 torr. It is suggested that PaO2 readings below 105 torr be confirmed by the standard bench method.
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An evaluation of the accuracy, perdision, and clinical safety of the IBC indwellling catheter electrode for the continuous monitoring of arterial oxygen tension during and after general anesthesia was made in a total of 62 patients. A comparison of the standard bench-type electrode (Radiometer) with the International Biophysics Corporation (IBC) electrode for the measurement of oxygen tension in tonometered blood also was performed. Three hundred and fifty comparisons in 51 patients were made of the indwelling electrode with a standard Radiometer unit and, while there was good correlation, there also was ome scatter. An additional small series of 44 comparisons in 11 patients was performed, the primary difference being that the electrode was maintained intr-arterially for approximately 1 day. In both in vivo studies there was excellent correlation but questionable precidion. Four IBC electrodes and eight Radiometer Pao2 electrodes in an additional study were compared at 11 different tonometered oxygen tensions in blood. The IBC electrodes measured oxyygen tension more accurately than did the Radiometer, and standard deviations were consistently smaller at all of 11 different oxygen tensions for the IBC unit. The authors believe that the poor precision within both in vivo studies might be due to the fact that the IBC probe, which was of unknown accuracy and precision, was compared to a standard device (the Radiometer) which in the in vitro investigation proved to be less accurate and less precise. No complications due to the insertion and maintance of this in vivo electrode were encountered. The authors suggest that the IBC method for measuring Pao2 continuously in vivo be considered as an alternative to intermittent gas analysis of oxygen tension.
This is an investigation of a technique for simultaneously measuring arterial oxygen tension (PaO2) and blood pressure continuously during and after surgical anesthesia. In 27 patients, a special T attachment was placed on the end of an indwelling arterial catheter so that pressurized dilute heparin could be flushed through continuously while blood pressure was being recorded by means of a transducer-oscilloscope system and PaO2 was being recorded through an indwelling polarograph oxygen tension (PO2) readout device. The electrode was left in the artery for an average of 16 hours; the average PaO2 during mechanical ventilation with the patient breathing 50 per cent oxygen was approximately 200 torr at the beginning of anesthesia; it dropped to 158 torr 6 hours later. The average PaO2 in the recovery room 1 hour postoperatively, with the patient spontaneously breathing approximately 30 per cent oxygen, was 122 torr. No significant complications were encountered during this investigation. We believe this dual technique to be a valuable monitoring tandem in the anesthetized and surgical intensive care patient.
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