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Biomedical subjects

M Hundeiker

Publications and source records attributed to M Hundeiker.

At least 73 records · Page 4Linked to original sources
PubMed1981

[Technic of delayed skin flap transplantation].

In 38 patients a "delayed skin flap transplantation" was performed after excision of malignant melanomas. The skin graft can be stored in a refrigerator at 4 degrees C for 2 weeks without damage to the transplant. The transplantation was usually done 4 days postoperatively. Advantages of this method seem to be a decreased risk of local infection, early mobilisation of the patient, and generally good cosmetic results.

Dermatologic Surgical Procedures↗
PubMed1980

[Strategies used by patients with lateral telangiectatic naevi to handle their problems].

Considering the suitableness of operative therapies for remarkable skin defects without progrediency or malignity, we studied patients' feelings, cognitions and ways of acting with a special questionnaire. The forms were filled in by 28 patients with lateral telangiectatic naevi and a control group of 60 persons with normally constituted skin. The results did not show significant differences between the two groups. Therefore, the indications for surgery or radiotherapy have to be set up very cautiously.

Adult↗
PubMed1980

[Reversible impairment of spermatogenesis induced by aromatic retinoid in guinea pigs (author's transl)].

Forty-one male guinea pigs were treated orally with high doses of aromatic retinoid (Ro 10-9359) 25 mg/kg/day in oleum arachidis for 6 weeks. Twenty-three animals were investigated at the end of this treatment. The remaining 18 animals were investigated after an additional retinoid-free interval of 6 weeks. A control group of 13 animals received oleum arachidis only. The histological investigation of the testes of the 23 animals studied immediately after the 6-week application of retinoid revealed reduced diameters of the seminiferous tubules, disorganization and desquamation of the seminiferous epithelium with decreased spermatogenetic activity and lack of mature elements. On the other hand, the 18 animals which were investigated 6 weeks after completion of retinoid treatment did not show any alterations, as compared to the control animals. Our results show that high systemic doses of aromatic retinoid clearly induce impairment of the spermatogenesis; however, all changes were reversible within 6 weeks after withdrawal of the drug.

Animals↗
PubMed1980

[Familial malignant melanoma and atypical disseminated moles (BK-mole syndrome)].

Report of a family with malignant melanomas and multiple atypical pigmented moles in three siblings. A 29 year old caucasian woman had a nodular melanoma. Twelve years ago, at the age of 23, her elder brother had been suffering from a melanoma with a solitary cerebral metastasis. Following radical surgical treatment, he has been well since that time. Their sister died with 21 years after inadequate treatment and generalisation of a melanoma in her temporal region. All patients had multiple atypical nevus cell nevus-like pigmented moles with irregular bizarre configuration, especially in the upper parts of the trunk. These findings correspond to the BK-mole syndrome. This heritable syndrome is not frequent, but important because of the necessity to keep all relatives of BK-mole patients under continuous dermatological control and to remove each suspicious lesion early enough.

Adult↗
PubMed1979

[Congenital hereditary hypotrychosis. Generalized autosomal dominant hypotrichosis with pili torti (hypotrichosis congenita hereditaria Marie Unna)].

Report on a family with numerous relatives in 7 generations suffering from hypotrichosis congenita hereditaria Marie Unna type. Personal investigations were possible in 29 persons. 19 of them presented the characteristic features of the syndrome with pili torti, generalized inborn hypotrichosis and a type of baldness resembling androgenetic alopecia.

Adolescent↗
PubMed1979

[Attempt at applying statistical methods to delimit melanoma types].

By means of the "multivariate variance analysis" ("MANOVA"; Friedrich and Olfert, 1977), we tried to differentiate the histologic types of malignant melanomas also by quantifiable criteria. The investigation depended upon data from 411 patients. Difficulties arose from incomplete data material. But in principle, the indication of this method is given in such problems. If the number of cases could be augmented, the method would be helpful as a support for diagnostic quality control.

Adolescent↗
PubMed1979

[Accuracy of the clinical diagnosis in malignant melanomas].

Histologic findings and clinical data of 411 patients with malignant melanomas treated in 1952 up to june 1977 reveal an improvement of diagnostic accuracy. Within the last years, fewer patients were referred to the clinic with extensive tumor growth or with metastases. A change from the levels of invasion V and IV to III is evident. Further improvement to level II and I with a corresponding smaller tumor thickness is appearing in outlines.

Adult↗
PubMed1979

[Vascular nevi and tumors of the skin].

Diagnosis and classification of dysontogenetic and neoplastic lesions of blood- and lymph-vessels depend upon the presence or absence of proliferating vascular elements and of non-involutive connective tissue and muscular wall structures. Angiectatic and angiokeratotic nevi, capillary and cavernous angiomas, glomangiomas and malignant vascular tumors are presented in a survey with special reference to frequent diagnoses.

Adolescent↗
PubMed1979

[Diagnostic problems in skin tumors].

Several starting-points for improvement of diagnostic accuracy in skin tumors are illustrated by examples: Frequencies and direction of diagnostic errors, as well as the value of diagnostic criteria need further investigations. Frequent "customary" diseases need more attention in medical textbooks, compared with less frequent "interesting" syndromes. Erroneous denominations and historical false classifications which are handed down in the literature demand correction. The possibility continues, that apparently clearly defined entities may decay; they may be replaced by new entities in consequence of new perceptions.

Diagnosis, Differential↗
PubMed1979

[The clinical picture of "circumscribed granuloma diseases"].

Characteristic findings, differential diagnosis and clinical course of the so-called "circumscript granulomas" (Granuloma anulare, necrobiosis lipoidica, Miescher's granulomatosis, disciformis, necrobiosis maculosa, granuloma multiforme, actinic granuloma, granuloma faciale and lethal midline granuloma etc.) are represented in a condensed clinical survey.

Diagnosis, Differential↗
PubMed1979

[Differential diagnosis of pigmented tumors].

Some frequent diagnostic problems and the most important clinical and histologic criteria in differential diagnosis of malignant melanomas, benign pigment cell nevi, melanotic epithelial neoplastic lesions and frequent haemosiderotic tumors are delineated in a condensed survey. Considering the variety of diagnostic errors, one should never treat respectively destroy pigmented tumors of the skin without histologic investigation.

Angiokeratoma↗
PubMed1978

[Clinical variations of keratoacanthomas].

Clinical variants of Keratoacanthomas are, besides the very frequent crateriform types, and the plate-shaped ones, Keratoacanthoma marginatum centrifugum, aggregated Keratoacanthomas, successive multiple Keratoacanthomas, and rare special forms like multiple eruptive Keratoakanthomas and Keratoacanthomas combined with Hyperplasia of sebaceous glands and epitheliomas. A detailed description of the different types is derived from their growth and their origin from supraseboglandular epithelium of hair follicles.

Diagnosis, Differential↗
PubMed1978

[Cryotherapy of the cylindroma syndrome].

Two patients with dermal Cylindromas were successfully treated with a special cryoapplicator. This small cryosurgical unit consists of a copper core of 645 g with a 1,5 cm insulating styropore body. At the one end, the cylindrical core has a projection bearing the therapeutic surface, at the other a thread, which takes up a manipulator. This serves the purpose of transfering the core into liquid gas and, after throughout cooling, into the styropore body. After half an hour of therapeutic use, the warmed core requires new cooling in liquid nitrogen or liquid air.

Adult↗
PubMed1978

[Classification of vascular neoplasms].

Neoplasms of blood and lymph vessels differ from angiectatic and angiokeratotic nevi by real proliferating growth. According to their features of growth and their wall structures, they are classified into three main groups: angiomas, glomangiomas and malignant vascular tumors. Within the angiomas on the one hand, capillary angiomas are classified into: planotuberous and tuberonodous angiomas of childhood and Kasabach-Merritt syndrome, multilocular hemangiomatosis, progressive multiple angiomas, tardive ("senile") angiomas, eruptive angiomas (granulomata pediculata), papular angioplasia, gemmangioma, and benign juvenile hemangioendothelioma. On the other hand, cavernous angiomas, i.e. arterial and venous cavernomas, as well as blue rubberbleb nevus, Mafucci's syndrome, angioleiomyoma, benign juvenile hemangiopericytoma and cavernous lymphangioma, form thick walled structures without involution. Glomangiomas occur as solitary, multiple systematized, and multiple disseminated and familiar forms. Within the group of malignant vascular tumors--Kaposi sarcoma, lymphangiosarcoma in lymphedema, hemangioendothelioma and angioplastic reticulosarcoma, hemangio- or lymphangiosarcoma, angioendotheliomastosis proliferans, rarity and increasing loss of characteristic differentiated structures give rise to difficulties in nosologic classification.

Diagnosis, Differential↗