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Biomedical subjects

M Hermans

Publications and source records attributed to M Hermans.

28 records · Page 2Linked to original sources
PubMed1985

Nutrient insulin secretagogues decrease 45Ca2+ efflux from islet cells by a mechanism other than the inhibition of the Na+-Ca2+ countertransport.

The mechanism whereby nutrient insulin secretagogues decrease 45Ca2+ efflux from islet cells is controversial. It was studied with mouse islets perifused with Ca2+-free solutions. In the presence of Na+, glucose and ketoisocaproate inhibited 45Ca2+ efflux by about 50%. Substitution of choline+ salts for Na+ salts decreased the efflux rate by 45%, but did not prevent glucose from decreasing it further. Ketoisocaproate also inhibited 45Ca2+ efflux, but less markedly than in an Na+ medium. Omission of Na+ decreased the efflux rate even when it was already lowered by glucose or ketoisocaproate. It is thus clear that nutrient insulin secretagogues decrease 45Ca2+ efflux from islet cells by a mechanism other than the inhibition of the Na+-Ca2+ countertransport, possibly by increasing sequestration of the ion in cellular organelles.

Animals↗
PubMedDate not supplied

Palatal sliding strip flap: soft tissue management to restore maxillary anterior esthetics at stage 2 surgery: a clinical report.

A new soft tissue flap design technique, called "the palatal sliding strip flap" (PSSF), has been developed to improve the soft tissue surgical results at stage 2 implant surgery. The purpose of this flap design is to help form papillae between implants and between natural teeth in the anterior area of the maxilla. The flap is designed and managed so that the palatal attached mucosa slides in a labial direction to create papillae and at the same time augment the labial ridge. This surgical approach is valid, predictable, and has a low risk-to-benefit ratio. This new flap design is indicated for a variety of clinical situations, especially for the problematic maxillary soft tissue reconstruction around teeth and implants.

Alveolar Ridge Augmentation↗
PubMedDate not supplied

[Microalbuminuria in a population of 653 patients with type 1 and 2 diabetes].

The aim of this retrospective study was to evaluate the prevalence of microalbuminuria in type 1 and 2 diabetic patients with or without high blood pressure levels. 653 patients were involved in the study [type 1: n = 413 (normotensive: n = 298; hypertensive: n = 115); type 2: n = 240 (normotensive: n = 93; hypertensive: n = 147)]. In type 1 diabetic patients, the prevalence of microalbuminuria was of 21 per cent. Microalbuminuria was also found in 28 per cent of type 2 diabetic subjects (p less than 0.10 vs type 1). The prevalence of microalbuminuria was significantly higher in hypertensive than in normotensive diabetic subjects (28 vs 20 per cent; p less than 0.05). Blood pressure in type 1 and 2 normotensive patients was significantly higher in subjects with than without microalbuminuria. We also observed higher HbA1 levels in microalbuminuric type 1 diabetic patients. Finally, we also assessed that the prevalence of diabetic chronic complications was higher in type 1 patients with than without microalbuminuria (p less than 0.05). This relationship was not evidenced in type 2 diabetic patients. In conclusion, the prevalence of microalbuminuria in a population of type 1 and 2 diabetic patients is high. We confirm in this study the relationship between microalbuminuria, blood pressure, and HbA1.

Adult↗
PubMedDate not supplied

Actinomycosis of the ano-rectum: a rare infectious disease mimicking carcinomatosis.

Abdominal actinomycosis is an infectious disease caused by Actinomyces israeli, a usual germ of the gastro intestinal tract. It gives unusual tumoral lesions with abcesses and fistulas. More rarely is abdominal actinomycosis at the end of the abdominal tube. Cope in 1949 said: "Actinomycosis occurs so seldom in the colon and the rectum that no surgeon, even if he be a proctologist is likely in a life time to see more than a few cases" (4). An anorectal actinomycosis case that looked like rectal cancer is reported. It was treated successfully by surgery and antibiotherapy. Some anatomopathologic and mainly histologic characteristics lead to the diagnosis. General and pathological aspects, symptoms, diagnosis, differential diagnosis and therapy of anorectal actinomycosis are discussed.

Actinomycosis↗
PubMedDate not supplied

[Hamartoma of the breast].

Two cases of hamartoma of the breast are presented. The clinical findings of this benign, rare lesion are not specific. It is characterized radiologically by its typical features of a clear or heterogeneous well defined picture with radiolucent zones on mammography. Echography provides no specific picture. Histologically, the tumor is composed of normal or dysplastic mammary tissue. Surgical treatment is mandatory, an enucleation can usually be performed.

Adult↗