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Biomedical subjects

M Henry

Publications and source records attributed to M Henry.

At least 235 records · Page 13Linked to original sources
PubMed1985

[Ultrastructural analysis of secretory cells and hyaline hemocytes with a "neoplastic" character in Mytilus galloprovincialis (Lamarck) collected from a natural polluted site (Bay of Fos)].

The comparative ultrastructural analysis of the digestive tubules of mussels sampled in a strongly hydrocarbons polluted neritic area and in another one reputed unpolluted, revealed important adulterations in the first one, namely that cells of digestive tubules and hyalinocytes within digestive gland display "neoplastic" disorders.

Animals↗
PubMed1985

A critical appraisal of impedance plethysmography in the diagnosis of acute deep venous thrombosis.

Compulsive performance of the test is paramount to obtaining good results. Sequential multiple tests with prolongation of the filling time to maximize venous filling and ultimately reaching a plateau is essential. Increase in venous filling by increasing the cuff pressure in the proximal lower thigh occluding cuff to 60 instead of 45 centimeters of water is helpful in obtaining optimum venous filling. Unrecognized patient apprehension or muscle contraction may be a reason for false-positive IPGs. Patient relaxation, local heat application or even electromyography attachment may be helpful. The IPG can be repeated after a few hours if a false-positive test result is suspected. If a test falls above the stop line, the NPV is so high that no repetition of the test is necessary and the limb is read out as showing no proximal venous thrombosis. If a test is normal or borderline, the test may be repeated with sequential testing until the test points seem to group together or a clear divergence of either normal or abnormal is achieved. If the contralateral limb is clearly normal and an abnormal test result is obtained in the suspected limb, the test is likely to be reliable. Bilateral abnormal IPGs, especially in the presence of congestive heart failure or severe edema, may indicate a false-positive test finding. Increased edema in the extremity decreases electrical resistivity and balancing the machine may become a technical problem.(ABSTRACT TRUNCATED AT 250 WORDS)

Humans↗
PubMed1984

Binding of disopyramide to alpha 1-acid glycoprotein in plasma measured by competitive equilibrium dialysis.

A modification of equilibrium dialysis in which alpha 1-acid glycoprotein and plasma compete directly for disopyramide has been used in conjunction with binding curves to measure the extent of the alpha 1-acid glycoprotein-disopyramide interaction. At concentrations in the therapeutic range, 80-90% of disopyramide was bound to alpha 1-acid glycoprotein for plasma from each of six healthy adults. Also, equilibrium dialysis data are presented, indicating that pH does not influence the binding of disopyramide within the therapeutic range.

Dialysis↗
PubMed1984

Interleukin 2 (IL2) is assigned to human chromosome 4.

The human gene for interleukin 2 (IL2) was assigned to chromosome 4 using human-mouse somatic cell hybrids and Southern filter hybridization of cell hybrid DNA. To identify IL2, a recombinant DNA probe ( pIL2 - 50A ) was used which contained a human interleukin 2 cDNA insert which hybridized to a 3.5-kb fragment in human DNA when cleaved with the restriction enzyme EcoRI.

Animals↗
PubMed1984

Electrophysiologic and manometric assessment of failed postanal repair for anorectal incontinence.

The reason for failure to improve fecal incontinence after postanal repair in idiopathic (neurogenic) anorectal incontinence is unknown. The authors have studied 20 patients whose anorectal continence was not improved after Parks' postanal repair. Anorectal manometry, single fiber EMG of the external anal sphincter muscle, and measurements of the pudendal nerve terminal motor latency were studied before and nine months after postanal repair. All 20 patients had evidence of reinnervation within the external anal sphincter muscle before operation; 17 had a raised pudendal nerve terminal motor latency and all 20 had low resting voluntary contraction anal canal pressures. No significant differences were found between the resting, voluntary contraction anal canal pressures and single fiber EMG fiber density values before or after postanal repair. However, a significant increase in the pudendal nerve terminal motor latency was found after postanal repair (P less than 0.001) using a student's paired t test. These results suggest that, in patients who are not rendered continent by postanal repair, a continuing neuropathic process takes place.

Adult↗
PubMed1983

[Central and peripheral coronary-pulmonary fistulae. Apropos of 4 case reports].

The authors report four cases of fistulae between coronary arteries and the main pulmonary artery or its branches. Proximal fistulae, often considered with coronary-cardiac fistulae (between coronary arteries and cardiac cavities, usually in the right heart) probably result from accessory coronary buds originating in the truncus arteriosus, on its pulmonary part, as in anomalous coronary arteries stemming from the pulmonary trunk. Two such cases are reported, including one in a girl with severe congenital mitral insufficiency. Peripheral fistulae probably do not result from a single mechanism, and their congenital or acquired origin is often difficult to determine, especially in adults. Nevertheless, in a 54-year-old female with angina by coronary steal, without any associated pulmonary disease, the fistula is probably congenital. On the other hand, in a boy who had a Blalock operation for Tetralogy of Fallot, the fistula is probably acquired, as part of the collateral circulation which developed after pleuro-pericardial symphysis. Such fistulae usually do not require surgery except in cases of coronary artery steal, which are exceptional in children but not infrequent in adults.

Adolescent↗
PubMed1982

The genesis and ultrastructural appearance of spontaneous renal lesions in the homozygous Gunn rat.

Deposition of bilirubin at the tip of the renal papilla has been studied in the infant homozygous Gunn rat. The deposits form during the 4th wk of life in ground substance along basement membranes of capillaries and tubules and along the borders of interstitial cells. Deposits also form in capillary lumens. The early ultrastructural appearances indicate that unconjugated bilirubin is not directly cytotoxic. This conclusion has important implications for the pathogenesis of enhanced nephrotoxicity in the homozygous Gunn rat and ultimately for the pathogenesis of analgesic nephropathy.

Animals↗
PubMed1982

Survival of infants born at 24 to 28 weeks' gestation.

Factors affecting the survival of 136 consecutive live-born infants delivered at 24 to 28 weeks' gestation during a 4-year period were analyzed. After careful assessment of gestational age, perinatal care for the fetus of at least 26 weeks' gestation was aggressive. Survival at 26 weeks was 45% and at 28 weeks, 92%. Multivariate analysis showed that the set of variables that best predicts neonatal outcome is gestational age, antepartum glucocorticoid administration, and resuscitation at birth.

Birth Weight↗
PubMed1982

[Acquired angioneurotic edema caused by acquired deficiency of C1 esterase inhibitor disclosing lymphoproliferative syndrome. Apropos of a case, review of the literature].

One case of acquired angio-neurotic oedema is described and discussed with the other cases recorded in literature since Caldwell's one in 1972. This entity is characterized by: --the late onset of angio-oedema but its presence only in about half cases, --a complement deficiency resulting from the lack of C1-esterase inhibitor, --the absence of familial identical cases, --the great frequency of associated illnesses overall lympho-proliferative diseases, --the therapeutic response to either etiologic treatment of the associated disease or to the symptomatic effect of drugs used in hereditary angio-neurotic oedema.

Aged↗