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Biomedical subjects

M Hanssens

Publications and source records attributed to M Hanssens.

At least 73 records · Page 4Linked to original sources

Subacute sclerosing panencephalitis: fundus changes and histopathologic correlations.

This paper describes the fundus changes in 2 patients with subacute sclerosing panencephalitis (SSPE). In both cases the ocular involvement preceded the neurological symptoms by several months. In one patient a localized serous detachment in the macular region was associated with retinal infiltrates and in the second patient an atypical unilateral macular chorioretinitis was first diagnosed. The diagnosis of SSPE was suspected when neurological signs appeared and it was confirmed by the typical EEG changes and especially by the high titers of measles antibodies in serum and CSF. The affected left eye of the second patient could be studied histopathologically and presented mainly pigment epithelial changes at the level of the scar, edema of the external plexiform layer, retinal folds and a detachment and rupture of the internal limiting membrane.

Adolescent↗

Scleral pockets and lyophilized sclera in retinal detachments.

For our buckling operations in retinal detachment, we prefer lyophilized sclera because it is well tolerated without tissue reaction, and very easy to handle. Its inertness is demonstrated by histopathological examination of sclera fragments taken during reoperations.

Freeze Drying↗

Corneal ultrastructural changes in Fabry's disease.

A case of Fabry's disease is reported. The findings of the corneal alterations with the light microscope as well as with the electron microscope are described. The diffuse corneal haziness seems to be due to small intracellular osmiophilic inclusions of the epithelium. There seems also to be a relation between the giant inclusions in the corneal epithelium, not yet described, and the clinical presence of punctiform grey opacities. The pathogenesis of the whorl-like opacities remains unsolved.

Adult↗

Statistical study of pseudopapillits vascularis.

In pseudopapillitis vascularis the male sex is preponderant. There are two peaks of frequency in the male as well as in the female group, although 72% of the cases appear between 51 and 70 years of age. The onset may be sudden or progessive. The most important aetiological factors are diabetes, arterial hypertension and arteriosclerosis. The disease is bilateral in 46% of the cases. The vision is less than 3/10 in 77% of the cases. An improvement of the visual acuity is observed in 52% of the unilateral cases, but only in 15% of the bilateral cases. The treatment is ineffective. The biopsy of the temporal artery shows an obvious arteriosclerosis in more than two-thirds of the cases.

Age Factors↗

Neovascularization after argon laser photocoagulation of macular lesions.

In three patients treated for macular degeneration with argon laser photocoagulation choroidal neovascularization occurred four to six weeks later at the photocoagulation site. Two of the patients were treated for angioid streaks of the macular region, the third patient was treated for disciform macular degeneration. Argon laser photocoagulation also induced neovascularization experimentally in pigmented rabbits.

Angiography↗