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Biomedical subjects

M Hanada

Publications and source records attributed to M Hanada.

At least 199 records · Page 11Linked to original sources

Sorbistin, a new aminoglycoside antibiotic complex of bacterial origin. I. Production, isolation and properties.

A strain of a new Pseudomonas species produced the aminoglycoside antibiotic complex, sorbistin, which was separated by ion-exchange chromatography into three bio-active components A1, A2 and B, and two bio-inactive components C and D. Sorbistins A1, A2 and B showed moderate intrinsic activity against a wide range of bacterial species and inhibited most of the aminoglycoside-resistant organisms. Sorbistin A1 exhibited the highest activity among the three bio-active components. Sorbistins showed low order of acute toxicity in mice.

Aminoglycosides↗

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