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Biomedical subjects

M Hamza

Publications and source records attributed to M Hamza.

At least 145 records · Page 8Linked to original sources

Benign extracerebral fluid collections: a cause of macrocrania in infancy.

In order to determine the frequency and natural history of benign extracerebral fluid collections, computed tomography reports from a period of 26 months at Oklahoma Children's Memorial Hospital were reviewed (total scans: 3,411). Bilateral frontal extracerebral fluid collections were found in 94 infants under 1 year of age. Eighty-two infants had computed tomography scans as part of the evaluation for macrocrania. Thirteen patients had the typical findings of benign extracerebral fluid collections but otherwise were completely asymptomatic. Longitudinal observation for up to 30 months failed to reveal any changes in neurologic status of these patients. Benign extracerebral fluid collections are a relatively common cause of macrocrania in infants. The presence of these fluid collections is not of immediate concern, providing that clinical evaluations fail to identify either neurologic or developmental abnormalities.

Cephalometry↗

Macro cisterna magna: a marker for maldevelopment of the brain?

Enlargement of the cisterna magna occurs in as many as 0.4% of reported patients and generally has been believed to represent a normal variant. Differentiation from Dandy-Walker malformations and other cystic structures has been emphasized. We reviewed 1,260 consecutive computed tomography reports in patients younger than 21 years of age and examined all scans in which enlargement of the cisterna magna was considered an isolated finding. Fourteen patients were identified (incidence: 1%). The primary reasons for obtaining computed tomographic scans included various clinical conditions but excluded symptoms indicative of posterior fossa disease. Developmental or neurologic abnormalities were present in 62% of these patients. Macro cisterna magna should not be dismissed as a normal variant, although the neurologic findings may not be specifically localized to the posterior fossa. This finding may be a marker for abnormal brain function most likely due to subtle disturbances in brain development.

Brain↗

[Behçet's disease].

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Behcet Syndrome↗

[Wegener's granulomatosis and pregnancy. A case].

Pregnancy concomitant with Wegener's granulomatosis is extremely rare: so far, only four cases have been published. The authors report a fifth case where the disease appeared during the post-partum period, a situation which has already been noted in two of the published cases. Interruption of a subsequent pregnancy was followed by a flare-up of the disease resulting in the patient's death. This suggests that post-partum and post-abortum are probably instrumental in the onset and deterioration of Wegener's granulomatosis. The two patients previously reported who received immunosuppressants combined with corticosteroids had no flare-up after delivery. It seems permissible to prescribe such a therapeutic combination before and after delivery or abortion, especially since the fear of foetal toxicity from these drugs seems to be exaggerated.

Abortion, Therapeutic↗

The effect of ammonia on olfactory epithelium and vomeronasal organ neuroepithelium of rabbits. A histological and histochemical study.

In recent studies, the vomeronasal organ (VNO), although vestigial and with unknown function in humans, was reported to be present in almost every person examined. In rabbits, it is a well-developed organ, one lying on each side of the nasal septum. Histologically it was found to contain neuroepithelium which is considered an accessory olfactory system taking charge of an olfactory discrimination different from that of olfactory epithelium. Experimental removal of the VNO in male animals reduces reproductive performance and aggression. In this study, the effects of prolonged exposure to ammonia vapor on the histological pattern and enzymatic activity of the olfactory epithelium and the VNO neuroepithelium of 30 adult male rabbits were investigated and compared with a control group. In the exposed animals, the supporting cells in both types of epithelia showed hyperplasia which was more marked in the olfactory epithelium. Manifestations of cytotoxicity were found more in the bipolar cells of the olfactory epithelium than in the VNO neuroepithelium. The enzymatic activity in the exposed group supported the histological results. The presence of the VNO neuroepithelium of the rabbit in a narrow duct with a minute nasal orifice could have some protective effects on the cells.

Alkaline Phosphatase↗

Transcatheter embolization of multiple pulmonary artery aneurysms in Behçet's syndrome. Report of a case.

Transcatheter embolization of a pulmonary artery aneurysm in Behçet's disease has rarely been attempted. A report is presented of a case with four pulmonary aneurysms and massive hemoptysis. Transcatheter embolization was successfully performed in three of these aneurysms, with clinical improvement during a follow-up period of 11 months. Technical problems, hazards, and indications for embolization in these patients are discussed.

Adult↗

[The etiology of hypercalcemia: a study of 47 cases in a hospital internal medicine service].

In this study, we are presented the clinical and the aetiologic features of 47 patients having hypercalcemia (total serum calcium > or = 2.7 mmol/l). Our results show a positive significantly correlation between the degree of the hypercalcemia and the severity of the clinical symptomatology. As for to the aetiology, the multiple myeloma, the hyperparathyroid and the neoplastic process constituted 78% of the total aetiology.

Aged↗

[Behcet's disease].

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Behcet Syndrome↗

Hereditary chondrocalcinosis in a Tunisian family.

A clinical and radiological survey of 77 members of a Tunisian family with hereditary chondrocalcinosis was performed. Articular chondrocalcinosis was documented by X-rays in 7 living members of 3 generations. No associated or secondary forms of the disease were found. Clinical features of the disease appeared early in life and radiologic involvement was extensive. The mode of inheritance appeared to be autosomal dominant with incomplete penetrance. Electron microscopy study of synovium and cartilage biopsies from one patient demonstrated calcium pyrophosphate dihydrate crystals. HLA typing revealed that all affected subjects bore the haplotype A1 B12 DR3.

Adolescent↗