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Biomedical subjects

M H Reed

Publications and source records attributed to M H Reed.

At least 73 records · Page 4Linked to original sources

The distal femoral defect: technetium-99m pyrophosphate bone scan results.

To determine the scintigraphic findings in children with distal femoral defects (or subperiosteal desmoids) the authors retrospectively examined 94 sets of radiographs and technetium-99m pyrophosphate bone scans of 54 children. Twenty-four examples of distal femoral defects were identified in 19 children. Only two children demonstrate focally increased uptake of radionuclide in the distal femur. The positive bone scan was caused by osteomyelitis in one of these patients and by metastatic lymphoma in the other. None of the 17 other children with distal femoral defects on radiography had a corresponding focal increase in uptake of radionuclide. The bone scan appears to be a useful method for confirming that a distal femoral defect is benign and, when positive, indicates the presence of other disease.

Adolescent↗

Performance evaluation of image-intensifier tubes.

A series of image quality measurements were obtained over a two-year period for eight image-intensifier tube fluoroscopic units used in clinical practice. The measurements were in agreement with a radiologist's opinion of the image quality for each tube. The results showed that some systems did not change significantly over the two-year period, while others deteriorated from acceptable to unacceptable image quality during this time. For this reason, it is recommended that measurements be obtained for all diagnostic fluoroscopic equipment at least semiannually to monitor image quality and remedy any changes before diagnostic accuracy is severely affected.

Fluoroscopy↗

Separating Larsen syndrome from the "arthrogryposis basket".

Many patients with larsen syndrome have been misdiagnosed as having arthrogryposis. Larsen syndrome should be considered in any child with multiple joint dislocations, particularly when the knees are involved. Spinal malalignment of a serious degree was encountered in five of the six patients we report and appears to have been underemphasized previously. Two of the patients had unusual ossicles of uncertain derivation at the elbow. This has been described only five times before.

Adult↗

Radiologic assessment of severity of acute asthma in children.

In this prospective study, chest radiographs were obtained in 23 children during 33 acute asthmatic episodes. The degree of hyperinflation was assessed radiologically by three methods and compared to the clinical findings. There was no correlation between the radiologic impression of hyperinflation and the clinical severity of the asthmatic episode.

Adolescent↗

Night blindness, characteristic facies, and skeletal abnormalities in two brothers.

Two brothers are described with a similar physical appearance characterised by minor periorbital anomalies, malar flatness, a maxillary overbite, retrognathia, sloping shoulders, joint hyperextensibility, and minor radiological anomalies. In addition, they had a slowly progressing night blindness, myopia, and extinguished electroretinograms. The mother had mild expression of some of the physical anomalies and a decreased electroretinogram response to red light. We have been unable to find any report of similarly affected children. The possible modes of inheritance are discussed.

Abnormalities, Multiple↗

Percutaneous puncture of abdominal cystic masses in children.

A technique of percutaneous puncture and opacification of cystic abdominal masses is outlined, and its diagnostic and therapeutic potential demonstrated in a series of 16 masses in 15 children. It is suggested as an alternative to ultrasound and computed tomography in certain situations.

Child↗

Geroderma osteodysplastica. A report of two affected families.

This paper describes two families in which four boys and two girls were affected with geroderma osteodysplastica. The major features of this syndrome include a droopy, jowly, prematurely aged appearance that has been likened by previous authors to the dwarfs in Walt Disney's 'Snow White.' Also, their skin lacks normal elastic recoil. The bones are osteoporotic and susceptible to fractures, particularly the vertebrae, which show compression with anterior wedging and biconcavity. The findings in the present families are compared with those in the originally reported family. There was a high degree of consanguinity between the parents in both of the present families and the previous hypothesis of X-linked inheritance is questioned.

Bone Diseases, Developmental↗

The radiology of intracranial tuberculosis in children.

Radiology provides valuable clues to the correct diagnosis of intracranial tuberculosis. Twenty-three children with this problem were reviewed. Fifteen had meningitis, 12 of whom had abnormal chest radiographs, nine of them suggestive of tuberculosis. Common neuroradiologic findings were minor suture separation, abnormal activity in the region of the sylvian fissure on brain scans, mild ventricular dilatation, and vasculitis. Among the eight patients with tuberculomas, abnormal chest radiographs were less common. Neuroradiologic abnormalities included evidence of increased intracranial pressure on skull radiographs, focal deep lesions on brain scans, and hydrocephalus and mass lesions on air studies. Most tuberculomas were calcified one year later.

Adolescent↗

Radiologic findings in acute childhood asthma.

One hundred and seventy-eight admissions of 142 children with acute asthma were reviewed and graded for clinical severity. Abnormalities including consolidation (21%), atelectasis (3%) and pneumomediastinum (2%) were found on chest radiographs, most commonly in patients with clinically moderate or severe acute asthma. Hyperinflation proved difficult to assess, but was present in only 67% of admissions using the criteria described. The frequency of complications detected justifies the use of chest radiographs in assessing children admitted to hospital for acute asthma.

Adolescent↗

Fractures and dislocations of the extremities in children.

A prospective study of 410 fractures seen in 398 children during 1 year was carried out. Fractures were more common on the left, and the upper extremities were more frequently injured than the lower extremities. The two commonest sites were the hand and the distal forearm. The radius was the bone most commonly fractured. Fifty-seven (13.9%) of the fractures involved epiphyses and 67 (16.3%) were torus fractures. Of the 398 patients 236 were males. There was a slightly increased incidence of fractures in the summer months and in older patients.

Adolescent↗

Radiology of airway foreign bodies in children.

Among 91 children with airway foreign bodies there were 10 with radiopaque foreign bodies. Seventy-four of the cases of non-opaque foreign bodies were unilateral. Seventeen had pulmonary consolidation or loss of volume and 33 had a unilateral hyperlucent lung. In 18 of the latter there was unilateral overinflation, but in 15 the hyperlucency was the result of pulmonary vasoconstriction. Twenty-three patients had normal routine inspiration radiographs; in 14 of these fluoroscopy or expiration films were obtained and air-trapping was demonstrated in 13. In twenty-three of the children the diagnosis was delayed. Fifteen of these had normal chest radiographs or unilateral hyperlucency alone. Since normal inspiration chest radiographs are frequently seen in cases of airway foreign bodies even when the diagnosis is delayed, it is strongly recommended that fluoroscopy or expiration films be obtained in any patient where the diagnosis is in doubt.

Adolescent↗

Radiologic features of miliary tuberculosis in children and adults.

We reviewed the radiologic features of 19 children and 26 adults with miliary tuberculosis. Children had a very high prevalence of associated lymph node enlargement compared to the adults (95% vs. 12%). Pulmonary consolidation was more common in children (42% vs. 12%). Pleural effusions were uncommon in both groups. The miliary pulmonary lesions cleared faster in children. Evidence of previous tuberculosis was seen in 31% of the adults but none of the children. Most of these differences in radiologic features between children and adults probably represent differences in pathogenesis for hematogenous spread in the two groups.

Adolescent↗

Pelvic fractures in children.

Eighty-four cases of pelvic fractures in children were reviewed. Most of them were the result of motor vehicle accidents. Thirty-nine per cent were classified as unstable, the most frequent type being diametric fractures. The others, most of which were pubic fractures, were classified as stable. Twenty-eight patients sustained fractures elsewhere and sixteen had associated visceral injuries.

Accidents, Traffic↗

Bronchopulmonary dysplasia and lung rupture in hyaline membrane disease: influence of continuous distending pressure.

Review of 158 patients with hyaline membrane disease was undertaken. The introduction of artificial ventilation with a positive end-expiratory pressure (IPPB and PEEP) has doubled the prevalence of pneumothorax, pneumomediastinum and interstitial emphysema from 20.7% to 39.7%). Continuous negative distending pressure during spontaneous ventilation (CNP) was associated with a prevalence of lung rupture similar to that occurring spontaneously (4.8%). No patient treated with CNP alone developed bronchopulmonary dysplasia. Patients treated with IPPB with PEEP had a marked decreased prevalence of bronchopulmonary dysplasia (17.2%) when compared to patients treated with IPPB alone (36.2%), probably related to the enhanced overdistension of relatively normal areas of the lung may be related to the increased prevalence of lung rupture seen during IPPB with PEEP.

Humans↗

The hypertelorism-hypospadias syndrome.

Recently, an association between telecanthus and/or hypertelorism and hypospadias has been reported in several families. We describe six more families in whom we have found this association. Seven of the eight affected individuals were males. The other was a girl with hypertelorism and a minor urethral abnormality. The mothers in all six families had hypertelorism and/or telecanthus. Mental retardation and cleft palate were also common in our families and those reported previously. The radiologic findings in our first family, which was reported elsewhere as the "branchio-skeletal-genital syndrome," are considered in detail and include skull abnormalities, maxillary hypoplasia, dentigerous cysts and vertebral abnormalities.

Adolescent↗

Skeletal metastases from retinoblastoma.

Four patients with skeletal metastases from retinoblastomas are presented. Radiologically, the metastases showed periosteal new bone formation and permeative-type bone destruction, particularly involving the long bones of the extremities, and they tended to be bilateral. The metastases resembled those of neuroblastoma and, to a lesser extent, medulloblastoma. The relationship between these three tumors is discussed.

Bone Development↗