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Biomedical subjects

M Gruner

Publications and source records attributed to M Gruner.

At least 127 records · Page 7Linked to original sources

[Upper digestive fiberscopy in paediatrics in hiatal hernia and gastrointestinal haemorrhage].

On the basis of their experience of upper digestive fiberscopy in paediatrics in hiatal hernia and gastrointestinal haemorrhage, the authors wish to point out the value of this technique as a complement to radiological investigations. They indicate the possibility, in a specialised centre of the everyday use of currently available fiberscopic equipment, from the neonatal period onwards, and emphasize the definite contribution of endoscopic findings in the definition of indications for surgery in the pathological states which they have chosen to illustrate here.

Adolescent↗

[The small left colon syndrome. 3 cases].

In the light of three cases of neonatal obstruction related to a small calibre descending colon, the authors review the main clinical and radiological signs and compare them with the data in the literature. This functional disturbance is related to immaturity of the intrinsic innervation of the colon which is especially common in low birth weight neonates or of diabetic mothers. Diagnosis is dependent upon enema using diluted uroangiographic hydrosoluble iodine contrast medium, which shows a disparity in calibre at the left colic angle. The differential diagnosis lies with Hirschsprung's disease. Functional ileus in premature infants, meconium ileus and the "small left colon syndrome" are related to the same pathogenisis: functional immaturity of the colon.

Colon↗

[Radiological implications of iatrogenic complications in neo-natal surgery (author's transl)].

The authors report 17 cases of iatrogenic complications occurring during the neonatal period over an interval of 5 years in a surgical service. Such complications concern the radiologist, either in their cause or their discovery. These cases are taken together with findings reported in the literature and lead the authors to draw conclusions with regard to the practical management of certain examinations in the neonatal period and the radiological surveillance of the newborn in a surgical department.

Barium Sulfate↗

[External fistulas of the small intestines in the newborn infant and child. Medical aspects and digestive resuscitation (19 cases)].

The prognosis in fistulae of the small intestine in the infant and child is totally different according to whether they develop following a simple operation involving the healthy small intestine or multiple or complicated operations on pathological bowel. Under these latter conditions, constant medico-surgical cooperation, modern techniques of renutrition (total parenteral renutrition or constant flow enteral nutrition), together with restoration of water/electrolyte balance and the treatment of infections give increasingly satisfactory results. In a series of 19 children, with 26 enterocutaneous fistulas, deaths were reduced to 4. Independently of recourse to surgery determined by local abdominal conditions (peritonitis, obstruction) or persistence of the fistula, the choice between total parenteral renutrition and constant flow enteral nutrition (C.F.E.N.) depend essentially upon the site of the fistula. When the latter is proximal the digestive tract may not be used, while C.F.E.N. may be employed when it is distal, sometimes resulting in cure without further surgery.

Child, Preschool↗

[Sub-adventitial traumatic rupture of the left renal artery (author's transl)].

On the basis of two cases of sub-adventitial traumatic rupture of the left renal artery, as well as data from the literature, the authors indicate the relative poverty of clinical signs of traumatic rupture of the renal arteries. They stress the value of early intravenous pyelography in lumbar trauma, with immediate arteriography in the presence of a non-functioning kidney, making conservative surgery possible.

Adolescent↗

Linoleic acid cytotoxicity to bovine lens epithelial cells: influence of albumin on linoleic acid uptake and cytotoxicity.

The high cytotoxicity of linoleic acid (LA) to cultured bovine lens epithelial cells is correlated with high uptake rates for the fatty acid (FA). Both, LA uptake and LA cytotoxicity strongly increase with the increasing LA-to-albumin molar ratio in the culture medium. Cellular uptake and cytotoxicity of LA can be competitively inhibited with the noncytotoxic palmitic acid. The findings may be of interest in view of the low albumin concentration in aqueous humor, resulting in extremely low buffering capacities for free FAs including LA, oleic acid and other cytotoxic cis-unsaturated free FAs, which are strongly raised in pathological situations like diabetes mellitus.

Animals↗