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Biomedical subjects

M Greenberg

Publications and source records attributed to M Greenberg.

At least 307 records · Page 17Linked to original sources
PubMed1970

Survey of workers exposed to dusts containing derivatives of Bacillus subtilis.

In a survey of 121 workers exposed to dusts containing derivatives of Bacillus subtilis, mainly proteolytic enzymes, skin tests showed evidence of sentiztation was higher among "atopic" subjects-16 out of tization was higher among "atopic" subjects-16 out of 25 (64%)-than among "non-atopic" subjects-32 out of 96 (33%). Reduced ventilatory capacity was found in 44% of sensitized workers compared with 14% of those not sensitized.

Bacillus subtilis↗
PubMedDate not supplied

A comparison of physician and patient perspectives on unconventional cancer therapies.

In two related studies about unconventional cancer therapies, patients and physicians were interviewed about their experiences and opinions. In this paper comparisons are made and implications discussed. There was general agreement among physicians and patients about the importance of providing access to information about unconventional approaches for interested patients. However, there were substantial differences in perspective on other issues, including: what constitutes 'unconventional', the helpfulness of typical physician responses to patients interested in or using unconventional therapies, the proper interface between practitioners of conventional and unconventional therapies, the reasons for communication problems (related to unconventional therapies) between physicians and patients, and the proper criteria for making decisions about unconventional therapies. Cancer specialists, family physicians and other health professionals need to look for ways to better understand and meet the needs of their patients with interests in unconventional approaches if they hope to preserve or improve relations.

Attitude of Health Personnel↗
PubMedDate not supplied

Identification of the tailspike protein from the Salmonella newington phage epsilon 34 and partial characterization of its phage-associated properties.

The lipopolysaccharide (LPS) of the Salmonella cell surface serves as the receptor for a very large number of bacterial viruses. The tailspike protein from these viruses recognizes the LPS as its initial receptor. It is proposed that the study of the P22 and epsilon 34 tailspike proteins could serve as a model for the study of the interaction of proteins with LPS. Toward this end, the tailspike protein of the epsilon 34 phage has been identified. The data suggest similarities between the epsilon 34 tailspike protein and the P22 tailspike protein. Some properties related to the interaction of the phage tailspike with its receptor are reported.

Adsorption↗
PubMedDate not supplied

Expression of WT1 in pediatric small cell tumors: report of two cases with a possible mesothelial origin.

The WT1 gene is normally expressed in fetal kidney and mesothelium, and its expression has been suggested as a marker for Wilms tumor and mesothelioma. We examined WT1 expression levels by reverse-transcriptase polymerase chain reaction (RT-PCR) in 38 childhood small-cell tumors including Wilms tumor, embryonal and alveolar rhabdomyosarcoma, Ewing sarcoma, lymphoma, desmoplastic small round-cell tumor (DSRCT), synovial sarcoma, extrarenal rhabdoid tumor, and two tumors that were atypical for this group of tumors. WT1 expression was only detected in Wilms tumor, rhabdoid tumor, and in these two cases of uncertain histogenesis. Both arose in the peritoneal cavity and by immunohistochemistry were diffusely positive for vimentin, keratin, and desmin. Tonofilaments were identified by electron microscopy in one of the cases. RT-PCR failed to detect the t(11;22) translocation associated with DSRCT in either case. Our results suggest that WT1 expression is an unusual feature of childhood non-Wilms tumors and, in the right setting, it may indicate a mesothelial origin. The expression of WT1 may play a role in mesodermal cells acquiring epithelial characteristics, a concept supported by the mixed epithelial and mesenchymal phenotype of these two cases.

Biomarkers, Tumor↗