Biomedical subjects

M Goudemand

Publications and source records attributed to M Goudemand.

At least 145 records · Page 8Linked to original sources

PubMed1975

[Experimentation in Lille with the passive hemagglutination test for the detection of Australia antigen. Comparison with other methods].

Among 5347 blood donors sera, the reverse passive hemagglutination test (RPH) enabled to detect 3,55% of HB ag (whereas 2,43% by EID). On the other hand, among 180 patients, the rate of positive reactions was observed to be the same for both techniques, which must be attributed to the presence of higher titer antigens. In the two series all positive reactions found by RPH method were also tested by RIA; this enabled to eliminate a great number (18% and 27%) of false positive reactions, which remain the disadvantage of the method. It must be also noticed that the complement fixation reaction gave the same results as the RIA.

Blood Donors↗

PubMed1975

[Blood stock management by computers in a transfusion center].

In large blood Transfusion Centers, blood stock management is quite difficult because of the numerous daily movements, the short storage time of blood products, the multiplicity of sample types, and, indeed, of blood antigens, etc. A data processing system has been established in the Blood Transfusion Center ofLille (170 000 bottles a year). From information codified in collection and in distribution departments, the computer is able to give to the authorities essential daily decision elements such as the knowledge of :--the exact profile of each collection (1 119 in 1974),--statistics of blood distributions,--available stock, classified by storage time, volume, blood group, etc. The computer contribution from the security point of view, as well as its utilization in phenotyped blood research is described here.

Blood Banks↗

PubMed1975

[Contribution to the isolation and study of the molecular weight of human factor VIII].

The authors describe some properties of highly-purified factor VIII concentrates isolated from human plasma. The fraction containing "factor VIII-complex" (factor VIII procoagulant activity, factor VIII related antigen and von Willebrand factor) is homogeneous by analytical ultra-centrifugation and its sedimentation coefficient is (see article). By gel filtration in high ionic strength buffer a low molecular weight fraction (LMW) with factor VIII procoagulant activity stronger than plasma's one has been isolated. This LMW fraction contains neither factor VIII related antigens nor von Willebrand factor. Its molecular weight determined by gel filtration is approximately 250,000.

Chromatography, Agarose↗

PubMed1974