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Biomedical subjects

M Glick

Publications and source records attributed to M Glick.

At least 55 records · Page 3Linked to original sources
PubMed1994

Necrotizing ulcerative periodontitis: a marker for immune deterioration and a predictor for the diagnosis of AIDS.

A multitude of oral lesions have been described in individuals infected with the human immunodeficiency virus (HIV). Few studies have attempted to correlate specific oral findings with immune status and HIV disease progression in the population reflecting the demographic profile of this epidemic. A prospective study was conducted among 700 ambulatory HIV-infected individuals seeking dental care between July 1, 1988 and June 30, 1992. Patients entered the study when they first applied for care and were followed at regular intervals unless death occurred before the conclusion of the study. The prevalence rate of necrotizing ulcerative periodontitis (NUP) was calculated for the entire population and specific to race, gender, and HIV transmission category. Survival analysis was used to estimate the cumulative probability of death within 24 months of a NUP diagnosis. The association between NUP diagnosis and CD4+ cell count below 200 cells/mm3 was also investigated, and it was found that HIV-infected individuals presenting with a diagnosis of NUP were 20.8 times as likely to have a CD4+ cell count below 200 cells/mm3 compared to HIV-infected individuals presenting without NUP. The prevalence of NUP was 6.3%. The lesion was significantly more common among men having sex with men (MSM), 8.4%, compared with non-MSM males, 1.8%. No racial difference was noted. The mean CD4+ cell count for patients with NUP was 51.8 cells/mm3 (SD +/- 71.2) while the median CD4+ cell count was 32.0 cells/mm3. The predictive value of a CD4+ cell count below 200 cells/mm3 in patients with this lesion was 95.1%. A cumulative probability of death within 24 months of a NUP diagnosis was 72.9%.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗
PubMed1993

Anhedonia and premorbid competence in young, nonpsychotic psychiatric inpatients.

Earlier studies have demonstrated a significant relation between scores on the Physical Anhedonia Scale--but not on the Perceptual Aberration Scale--and premorbid social adjustment in schizophrenics (Chapman, Chapman, & Raulin, 1976, 1978; Schuck, Leventhal, Rothstein, & Irizarry, 1984). A similar relation between scores on these 2 scales and interpersonal competence in college students has also been noted (Beckfield, 1985; Haberman, Chapman, Numbers, & McFall, 1979; Numbers & Chapman, 1982). The present study extends this work by examining the relation of premorbid adjustment to scores on these 2 scales among young, nonpsychotic psychiatric inpatients. Consistent with the earlier findings, anhedonic Ss had poorer premorbid social competence when compared with nonanhedonic Ss, whereas no relation was found between scores on perceptual aberration and premorbid social competence.

Adolescent↗
PubMed1993

Oral mucosal bacillary epithelioid angiomatosis in a patient with AIDS associated with rapid alveolar bone loss: case report.

Oral manifestations of bacillary epithelioid angiomatosis have been described in the literature, but without histopathologic evidence confirming the presence of the etiologic bacilli. The clinical and histopathologic similarities between bacillary epithelioid angiomatosis and Kaposi's sarcoma may have contributed to confusion in diagnosis and treatment of the latter. Furthermore, inclusion of bacillary epithelioid angiomatosis in the differential diagnosis of proliferative vascular lesions may help to clarify the etiology, pathology and epidemiology of these lesions. This article is the first report of the intraoral manifestation of bacillary epithelioid angiomatosis with histopathologic documentation of the causative pathogen.

AIDS-Related Opportunistic Infections↗
PubMed1993

Social competence among cocaine abusers: moderating effects of comorbid diagnoses and gender.

Levels of social competence and maladaptive behaviors were examined among 184 male and 85 female treatment-seeking cocaine abusers. Social competence was assessed based on indices of functioning at work and in relationships, maladaptive behaviors included severity of drug and legal problems, and difficulties in interpersonal relationships. Consistent with developmental interpretations, results indicated that addicts with comorbid depression had higher social competence than those with comorbid antisocial personality disorders. In contrast with research on other psychiatric groups, female addicts had lower social competence than males; however, they also had lower levels of maladaptive behaviors. Findings are discussed in terms of implications for preventive interventions and treatment for drug abusers.

Adult↗
PubMed1992

Evaluation of prognosis and survival of the HIV-infected patient.

HIV disease, once considered an acute disease with a 100% mortality rate but a very short symptomatic stage, has begun to emerge as a preventable, treatable, chronic disease. Interactions between patients, dentists, and physicians are essential to gain the information necessary to provide appropriate dental care for both short-term and long-term survivors. The prognosis and survival time of the dental patient may influence treatment protocols and necessitate modified dental procedures. Certain clinical and laboratory parameters, which may be useful indicators of disease progression, need to be recognized by the dental clinician. These parameters include systemic signs, symptoms, and serologic data as well as intraoral manifestations associated with HIV disease. Although a perfect classification system for progression of HIV disease does not exist, trends among larger cohorts may enable health care providers to estimate the prognosis and survival of HIV-infected patients on an individual basis. This article presents clinical and laboratory parameters that indicate HIV disease progression. Providers who care for HIV-infected patients need to consider these parameters to establish an appropriate and flexible treatment plan based on changes in the patient's medical status.

Acquired Immunodeficiency Syndrome↗