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Biomedical subjects

M Gheorghiu

Publications and source records attributed to M Gheorghiu.

110 records · Page 7Linked to original sources

[The ocular manifestations in systemic lupus erythematosus].

Retinal involvement in systemic lupus erythematosus is dominated by a microangiopathy of unknown aetiology, with occlusive consequences. Although cases of severe retinal ischaemia have been recently described, from a statistic point of view, the occlusive phenomena seem to have declined over the last decades, under the influence of a better therapy and follow-up of the disease. The relatively high incidence of papilloedema and the fact that this oedema might be unilateral or asymptomatic are pointed out. The importance of ophthalmic examination in patients with SLE-like syndromes or in seronegative cases of SLE is revealed. Other ocular manifestation of the disease are reviewed.

Eye Diseases↗

[Cataractogenesis and repair processes].

The main biochemical processes involved in cataractogenesis are reviewed: nonenzymatic glycosylation of crystallins, polyol pathway, increased proteolysis, role of the free radicals, significant changes in lipid and mineral contents of the lens. Every mechanism is discussed in detail, providing the ophthalmologists with essential biochemical data, and the links between the different biochemical events are stressed out.

Cataract↗