Biomedical subjects
Publications and source records attributed to M Ganter.
After giving a short review of the different types of leukosis in the pig a leukosis in a Göttingen miniature breeding sow is described. The clinical symptoms were nonspecific, the pathomorphological signs were characterized by hepato- and splenomegaly and leukotic changes in kidneys and lymph nodes. By means of hematologic examinations a chronic myeloic leukosis could be diagnosed.
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Reference values are essential for the interpretation of cytological findings in bronchoalveolar-specimens from healthy and diseased pigs, and also for studies on local immunity of the porcine lung. Values were calculated from 164 piglets out of six closed herds based on cellular bronchoalveolar lavage (BAL) data. The piglets were preselected by criteria of pulmonary health and total as well as differential cell count were performed. The values established were: total cell count 1-4.5 Giga litre-1, alveolar macrophages 90-99 per cent, lymphocytes 0-9 per cent, polymorphonuclear neutrophils 0-8 per cent, blastocytes 0-2 per cent, polymorphonuclear eosinophils and basophils 0-1 per cent.
Osteochondritis dissecans is most frequently seen at the knee, the elbow and the ankle joint. The localisation at the humeral head is very rare. There were 7 cases like this reported up to now. We present two more patients with osteochondritis dissecans of the humeral head; a 26-year-old man and a 36-year-old woman. For diagnosis and follow-up roentgenograms and MRI are used. MRI even helps to decide which operative strategy should be followed. Drilling of the sclerotic margin resulted in a satisfactory bony reintegration of the fragment in our male patient. The female patient refused an arthroscopy of her shoulder joint.
Rumen acidosis was provoked in 13 cross-bred sheep by feeding oat (32 g/kg body weight) or wheat of different grinding levels (26 g/kg). Development of the diet-related disease was studied in 8 fistulated sheep fitted with a permanent rumen cannula and with implanted jugular vein catheter by analysing blood and rumen fluid sampled up to 48 hours after feed intake. Ingesta of the different segments of the digestive tract were collected from 5 sheep, necropsied 8 and 12 hours after feeding respectively. Concentrations of glucose, L- and D-lactate were measured in blood and digesta by enzymatic methods. Concentrations of amylopolyglucans and pH values were analysed in the digesta. Whereas the plasma concentration of glucose and L-lactate rose with a maximum at 8 to 12 hours after feeding, that of D-lactate was maximally increased after 24 hours. High concentrations of amylopolyglucans, glucose, L- and D-Lactate were found in the whole digestive tract 8 and 12 hours after feed intake. It is concluded from the results obtained that sheep show characteristics of monogastric intestinal digestion with the release of considerable amounts of glucose and of both lactate isomers after feeding fine distributed starch.