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Biomedical subjects

M Gangemi

Publications and source records attributed to M Gangemi.

99 records · Page 6Linked to original sources

Sturge-Weber disease without facial nevus.

A rare case of Sturge-Weber syndrome without facial nevus and epileptic seizures is reported. The other cases of incomplete form of the disease reported in the literature showed occipital calcification and epileptic seizures without facial nevus, while in the present case also the convulsions were absent. The possible pathogenic mechanism is discussed. The CT findings of these incomplete forms include unilateral or often bilateral occipital calcifications with no evidence of contrast enhancement. The Authors conclude that the radiologic finding of bilateral gyriform calcifications in the occipital region must suggest the diagnosis of Sturge-Weber disease even in the absence of facial nevus and epileptic seizures.

Adult↗

Intracranial lipomas. Diagnostic and therapeutic considerations.

Fourteen cases of intracranial lipomas are reported and 200 cases from the literature are reviewed. Intracranial lipomas are rare lesions of developmental origin, which mainly occur in the region of the corpus callosum, more rarely in the ambient, interpeduncular, cerebellopontine angle and sylvian cisterns. Although they are usually asymptomatic, they can sometimes show neurological symptoms, mainly epileptic seizures. Computerized tomography and magnetic resonance imaging usually lead to the diagnosis, because of the very low-density attenuation values of lipomas on CT scan and the short T1 and T2 on magnetic resonance. A direct surgical approach is only rarely indicated, whereas cases associated to hydrocephalus require a CSF shunt. The anticonvulsivant therapy usually results in remission of the seizures.

Adolescent↗

Hypertrophy of the ligamenta flava of the cervical spine. Clinico-radiological correlations.

Among 1,000 myelographies performed between 1974 and 1983, 22 patients with isolated hypertrophy of the ligamenta flava of the cervical spine have been selected and their neurological troubles correlated with the radiological findings. The degree of neurological involvement resulted in relation with the degree of hypertrophy of the ligaments, the diameter of the spinal canal and the number of spaces involved by compression. The radiological diagnosis and the indications to surgery are discussed.

Acute Disease↗

[Epilepsy caused by vascular insufficiency as a result of a malformation in a child].

The Authors report a case of a 7-year-old boy with focal epileptic seizures; cerebral panangiography revealed a "coiling" of the right internal carotid artery, a scarcely visualized right posterior cerebral artery, and a diffuse hypovascularisation of the right cerebral hemisphere. They emphasize the possible relation between the vascular insufficiency and the epileptic seizures and they point out the possible role of congenital vasal malformations, as coiling and hypoplasia, in the origin of epilepsy in infancy.

Abnormalities, Multiple↗