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Biomedical subjects

M G Lind

Publications and source records attributed to M G Lind.

46 records · Page 3Linked to original sources
PubMedDate not supplied

Evaluation of some prognostic factors in small squamous cell carcinoma of the mobile tongue: a multicenter study in Sweden.

In a retrospective study of 58 patients from all over Sweden, treated for small squamous cell carcinoma of the mobile tongue (T1N0M0), different prognostic factors were evaluated. A partial glossectomy was performed as primary treatment in all patients. The cancer recurred in 28 (38%) of 58 patients. One of 7 patients with only local recurrence, and 9 of 14 with recurrence in the neck died of their disease. The relative survival rate was 77%. Of the prognostic factors tested, tumor thickness was found to be the most significant. In patients with tumor thickness was found to be the most significant. In patients with tumor thickness exceeding 10 mm, recurrences occurred in 58% (P less than 0.0048), and 87% (P less than 0.0164) died of their cancer. This represents a statistically significant higher degree when compared with tumor thickness of less than 10 mm. Elective treatment of the neck nodes is recommended in epidermoid cancer of the mobile tongue when tumor thickness exceeds 10 mm, even in stage I tumors (i.e., the surface extension diameter is smaller than 20 mm at most).

Adult↗
PubMedDate not supplied

Functional status and coping in patients with oral and pharyngeal cancer before and after surgery.

BACKGROUND: Few studies, prospective or retrospective, exist that describe the quality of life of patients with oral or pharyngeal cancer. This study describes functional status, measured by the sickness impact profile (SIP), and coping, measured by the sense of coherence (SOC) scale, in a group of patients treated by surgery for oral or pharyngeal cancer. METHODS: Forty-two patients, divided into two groups, participated in the study. Twenty-seven patients completed SIP and SOC scale 12 months after treatment (the 12-month follow-up group), and 15 patients completed SIP and SOC scale before surgery and SIP 2-4 months and 12 months after treatment (the prospective group). The patients were also classified according to the extensiveness of their surgery: minor, moderate, or major. RESULTS: The psychosocial and physical functioning as well as the functions of recreation/pastimes, sleep/rest, home management, work, and eating were rated as being impaired 2-4 months and also 12 months after treatment. However, the obtained values were spread over a wide range, with large individual differences. Functional limitations were related to more extensive surgery and also to less successful coping. CONCLUSION: This study reveals the need of individualized rehabilitation for these patients, and that the SIP and the SOC scale may serve as evaluation tools in a rehabilitation program.

Activities of Daily Living↗
PubMedDate not supplied

Discrimination of purulent from nonpurulent maxillary sinusitis. Clinical and radiographic diagnosis.

For the rational treatment of sinusitis, it is essential to distinguish sinusitis of bacterial origin from that of other etiologies. In maxillary sinusitis, antral purulence indicates a significant amount of pathogenic bacteria, whereas the presence of bacteria seems to be of less or no relevance in nonpurulent sinusitis. Hence, from a therapeutic point of view one important diagnostic goal is the differentiation of purulent from nonpurulent sinusitis. In this respect clinical examination is fairly reliable. Sinus radiography cannot distinguish purulent from nonpurulent sinusitis and offers few advantages when deciding on antibiotic therapy. Antral aspiration offers the most comprehensive information on which to base a reliable diagnosis.

Biopsy, Needle↗
PubMedDate not supplied

Radiosialometry. 1. A method for evaluation of salivary gland disorders.

The temporal course of the total 99Tcm40 acumulation in the parotoid glad after fast intravenous injection of the readionucleotide, is studied by examination with quantitative radiosialometry. The method adopted is based on the use of two collimated, symmetrically located and opposite placed NaI-detectors. The normal ranges of five evaluation parameters are obtained from a control material of 100 parotoid glands in 50 individuals without disorders of the parotoid glands. The reproducibility of these five evaluation parameters is estimated and the sensitivity and the detectability of the parameters as well as different sources of variation are discussed. Classification boundaries between normal and abnormal valves values are arbitrarily chosen form the normal ranges.

Adolescent↗
PubMedDate not supplied

Radiosialometry. II. The diagnostic accuracy of different evaluation parameters.

The temporal course of 99TcmO4 accumulation in the parotid gland after fast intravenous injection of the radionuclide was measured quantitatively by radiosialometry in 32 patients suffering from inflammatory or neoplastic diseases of the parotid glands. The diagnostic accuracy of five different evaluation parameters was compared. It was found that without reducing diagnostic accuracy, the method used could be simplified by omitting three of the five evaluation parameters. This implies a shortening of the measuring time from 18 to 10 minutes. The diagnostic accuracy of radiosialometry in 14 cases with a general engagement of the parotid parenchyma (irradiation damage, collagen sialosis and chronic recurrent parotitis) was high. Thus, all these 14 cases had abnormal radiosialometric values. Parotid tumours not causing extensive destruction of the parotid parenchyma were not detected by this method.

Collagen Diseases↗
PubMedDate not supplied

A swab technique for sialometry. Normal range.

A modification of the swab method for sialometry is described. The individual secretions from the right parotid gland, left parotid gland and both submandibular glands together were collected, by use of cotton swabs after submaximal stimulation by citric acid. Five evaluation parameters and their normal ranges and variances are described from a material of 150 control individuals without sign of salivary gland impairment. The measurement is performed within five minutes, it is simple and convenient both for the patient and the staff. Therefore the method described is well suited for routine clinical use.

Humans↗